Maturitas publishes 2013 update on diagnosis and management of osteoporosis

Update presented by National Osteoporosis Guideline Group

2013-06-19

(Press-News.org) Amsterdam, June 19, 2013 – Elsevier, a world-leading provider of scientific, technical and medical information products and services, announced today the publication of the National Osteoporosis Guideline Group (NOGG) Update 2013 on diagnosis and management of osteoporosis in postmenopausal women and older men in the journal Maturitas.

Published in 2009 in Maturitas, the original guidelines have been highly cited and this update is timely with an additional focus on the management of glucocorticoid-induced osteoporosis, the role of calcium and vitamin D therapy and the benefits and risks of long-term bisphosphonate therapy. In all these areas, there have been new developments over the past few years that have had an impact on clinical practice and require modifications and/or additions to previous guidance.

The recommendations in the guidelines are intended to aid management decisions but do not replace the need for clinical judgement in the care of individuals in clinical practice.

### These and other recommendations presented are published in the article: "Diagnosis and management of osteoporosis in postmenopausal women and older men in the UK: National Osteoporosis Guideline Group (NOGG) Update 2013" by J.E. Compston, Claire Bowring, Alun Cooper, Cyrus Cooper, Cyril Davies, Roger M Francis, John A Kanis, David Marsh, Eugene V McCloskey, David M Reid and Peter Selby. The article appears as an article in press in Maturitas (June 2013), published by Elsevier.

Original guidelines published in 2009: "Guidelines for the diagnosis and management of osteoporosis in postmenopausal women and men from the age of 50 years in the UK" by J. Compston, A. Cooper, C. Cooper, R. Francis, J.A. Kanis, D. Marsh, E.V. McCloskey, D.M. Reid, P. Selby, M. Wilkins, on behalf of the National Osteoporosis Guideline Group (NOGG). The article appears in Maturitas, Volume 62, Issue 2, (February 2009), published by Elsevier.

Notes for Editors Full text of both articles are available to credentialed journalists upon request, contact newsroom@elsevier.com. For further details about the clinical guide or to contact the authors or EMAS, contact g.peoples@elsevier.com or +31 20 485 3323

About NOGG The National Osteoporosis Guideline Group (NOGG) was established to provide a clinical guideline for the management of men and women at high fracture risk, particularly to address the need to integrate the expression of a patient's fracture risk as a 10-year probability (the output from FRAX®) with current clinical management of osteoporosis. This included the need to define thresholds for bone mineral density measurement and treatment. http://www.shef.ac.uk/NOGG/index.html

About Maturitas Maturitas is an international multidisciplinary peer reviewed scientific journal of midlife health and beyond, publishing original research, reviews, consensus statements and guidelines. The scope encompasses all aspects of postreproductive health in both genders ranging from basic science to health and social care. http://www.maturitas.org/ http://www.journals.elsevier.com/maturitas

About Elsevier Elsevier is a world-leading provider of scientific, technical and medical information products and services. The company works in partnership with the global science and health communities to publish more than 2,000 journals, including The Lancet and Cell, and close to 20,000 book titles, including major reference works from Mosby and Saunders. Elsevier's online solutions include ScienceDirect, Scopus, Reaxys, ClinicalKey and Mosby's Suite, which enhance the productivity of science and health professionals, and the SciVal suite and MEDai's Pinpoint Review, which help research and health care institutions deliver better outcomes more cost-effectively.

A global business headquartered in Amsterdam, Elsevier employs 7,000 people worldwide. The company is part of Reed Elsevier Group plc, a world leading provider of professional information solutions. The group employs more than 30,000 people, including more than 15,000 in North America. Reed Elsevier Group plc is owned equally by two parent companies, Reed Elsevier PLC and Reed Elsevier NV. Their shares are traded on the London, Amsterdam and New York Stock Exchanges using the following ticker symbols: London: REL; Amsterdam: REN; New York: RUK and ENL.

ELSE PRESS RELEASES FROM THIS DATE:

Antioxidant shows promise in Parkinson's disease

2013-06-19

Diapocynin, a synthetic molecule derived from a naturally occurring compound (apocynin), has been found to protect neurobehavioral function in mice with Parkinson's Disease symptoms by preventing deficits in motor coordination. The findings are published in the May 28, 2013 edition of Neuroscience Letters. Brian Dranka, Ph.D., postdoctoral fellow at the Medical College of Wisconsin (MCW), is the first author of the paper. Balaraman Kalyanaraman, Ph.D., Harry R. & Angeline E. Quadracci Professor in Parkinson's Research, chairman and professor of biophysics, and director ...

Staging system in ALS shows potential tracks of disease progression, Penn study finds

2013-06-19

PHILADELPHIA - The motor neuron disease Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's Disease, progresses in a stepwise, sequential pattern which can be classified into four distinct stages, report pathologists with the Perelman School of Medicine at the University of Pennsylvania in the Annals of Neurology. This post-mortem staging of ALS brain and spinal cord tissues shows, for the first time, how the fatal degenerative disease may progress from one starting point in the central nervous system to other regions of brain and spinal cord. As evidence mounts ...

The rhythm of the Arctic summer

2013-06-19

This news release is available in German. Our internal circadian clock regulates daily life processes and is synchronized by external cues, the so-called Zeitgebers. The main cue is the light-dark cycle, whose strength is largely reduced in extreme habitats such as in the Arctic during the polar summer. Using a radiotelemetry system a team of researchers from the Max Planck Institute for Ornithology have now found, in four bird species in Alaska, different daily activity patterns ranging from strictly rhythmic to completely arrhythmic. These differences are attributed ...

U-M researcher and colleagues predict possible record-setting Gulf of Mexico 'dead zone'

2013-06-19

ANN ARBOR—Spring floods across the Midwest are expected to contribute to a very large and potentially record-setting 2013 Gulf of Mexico "dead zone," according to a University of Michigan ecologist and colleagues who released their annual forecast today, along with one for the Chesapeake Bay. The Gulf forecast, one of two announced by the National Oceanic and Atmospheric Administration, calls for an oxygen-depleted, or hypoxic, region of between 7,286 and 8,561 square miles, which would place it among the 10 largest on record. The low end of the forecast range is well ...

British women 50 percent less likley to recieve treatment for common menopausal symptoms

2013-06-19

Crawley, UK-- New data, published today in Menopause International, suggests that post-menopausal women in Britain are experiencing less sex, and less satisfying sex compared to their European and North American counterparts1, because they are considerably less likely to access appropriate treatment for a common, taboo condition called vaginal atrophy1. The first-of-its-kind study, called the CLarifying vaginal atrophy's impact On SEx and Relationships (CLOSER) study, showed that British post-menopausal women with vaginal atrophy are more likely to experience less sex1, ...

No danger of cancer through gene therapy virus

2013-06-19

In fall 2012, the European Medicines Agency (EMA) approved the modified adeno-associated virus AAV-LPL S447X as the first ever gene therapy for clinical use in the Western world. uniQure, a Dutch biotech company, had developed AAV-LPL S447X for the treatment of a rare inherited metabolic disease called lipoprotein lipase deficiency (LPLD) which affects approximately one or two out of one million people. The disease causes severe, life-threatening inflammations of the pancreas. Afflicted individuals carry a defect in the gene coding for the lipoprotein lipase enzyme which ...

Outlook is grim for mammals and birds as human population grows

2013-06-19

COLUMBUS, Ohio – The ongoing global growth in the human population will inevitably crowd out mammals and birds and has the potential to threaten hundreds of species with extinction within 40 years, new research shows. Scientists at The Ohio State University have determined that the average growing nation should expect at least 3.3 percent more threatened species in the next decade and an increase of 10.8 percent species threatened with extinction by 2050. The United States ranks sixth in the world in the number of new species expected to be threatened by 2050, the research ...

University of Tennessee professor finds prehistoric rock art connected; maps cosmological belief

2013-06-19

It is likely some of the most widespread and oldest art in the United States. Pieces of rock art dot the Appalachian Mountains, and research by University of Tennessee, Knoxville, anthropology professor Jan Simek finds each engraving or drawing is strategically placed to reveal a cosmological puzzle. Recently, the discoveries of prehistoric rock art have become more common. With these discoveries comes a single giant one—all these drawing and engravings map the prehistoric peoples' cosmological world. The research led by Simek, president emeritus of the UT system and ...

New data on islet autoantibodies in young children defines early type 1 diabetes development

2013-06-19

New York, NY, June 19, 2013 – A decade-long JDRF-funded study led by the Institute of Diabetes Research in Helmholtz Zentrum München, Germany, is providing a deeper understanding of the link between autoantibodies and the risk of developing type 1 diabetes (T1D), highlighting the importance of pre-diabetes research into possible preventions for the disease. The study, "Seroconversion to Multiple Islet Autoantibodies and Risk of Progression to Diabetes in Children," was published today in The Journal of the American Medical Association. Researchers in Colorado (DAISY study), ...

Breakthrough research of essential molecule reveals important targets in diabetes and obesity

2013-06-19

DETROIT – Insulin is the most potent physiological anabolic agent for tissue-building and energy storage, promoting the storage and synthesis of lipids, protein and carbohydrates, and inhibiting their breakdown and release into the circulatory system. It also plays a major role in stimulating glucose entry into muscle tissue, where the glucose is metabolized and removed from the blood following meals. But gaps exist in understanding the precise molecular mechanisms by which insulin regulates glucose uptake in fat and muscle cells. A research team led by Assia Shisheva, ...

Maturitas publishes 2013 update on diagnosis and management of osteoporosis

ELSE PRESS RELEASES FROM THIS DATE:

LAST 30 PRESS RELEASES: