PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Use of simple rule in children's ankle injuries reduces use of radiography by 22 percent

Low Risk Ankle Rule clinical trial

2013-08-12
(Press-News.org) Radiography is widely used in diagnosing ankle injuries, with 85%–95% in pediatric injuries, although only 12% of these show fractures.

"Radiography is unnecessary for most children's ankle injuries, and these high rates of radiography needlessly expose children to radiation and are a questionable use of resources," writes Dr. Kathy Boutis, a pediatric emergency department physician at the Hospital for Sick Children (SickKids) and the University of Toronto, with coauthors.

The Low Risk Ankle Rule is highly accurate at identifying fractures and can potentially reduce the need for radiography by 60%. It states that if a child with an ankle injury has a low-risk examination, ankle radiography may not be necessary to further exclude a high-risk ankle injury. If a subset of minor lateral ankle fractures is missed, evidence shows that these are exceptionally stable and low risk for any future issues and can be treated like an ankle sprain. Reducing radiography can lower exposure to low levels of radiation, contain costs and speed up treatment.

Researchers implemented the Low Risk Ankle Rule in 6 Canadian emergency departments to determine whether it reduced the use of radiography in children. The study involved 2151 patients (1055 at intervention and 1096 at control sites) between the ages of 3 and 16 years who presented at an emergency department with a nonpenetrating ankle injury. By applying the rule, the use of ankle radiography was reduced by about 22%. This reduction was consistent in different emergency departments and is similar to the Ottawa Ankle Rule used with adults.

"The implementation of the Low Risk Ankle Rule led to a significant decrease in imaging, associated increase in clinically important fractures being missed or decrease in patient or physician satisfaction," write the authors. "The ankle rule has potential broad applicability to emergency departments throughout most of the developed world, and widespread implementation of this rule could safely lead to reduction of unnecessary radiography in this radiosensitive population and a more efficient use of health care resources."

### END


ELSE PRESS RELEASES FROM THIS DATE:

'Dark-horse' molecule is a potential new anti-cancer target

2013-08-12
Contact: Vanessa Solomon solomon@wehi.edu.au 61-393-452-971 Walter and Eliza Hall Institute Rachel Steinhardt rsteinhardt@licr.org 212-450-1582 Ludwig Institute for Cancer Research 'Dark-horse' molecule is a potential new anti-cancer target Australian researchers have identified a molecule called interleukin-11 as a potential new target for anti-cancer therapies. Until now, the importance of interleukin-11 in cancer development has been underestimated, but researchers have recently identified this molecule as a 'dark horse' for the development of cancer. ...

Aggressive breast cancers may be sensitive to drugs clogging their waste disposal

2013-08-12
Boston, Mass., August 12, 2013 – In a new paper in Cancer Cell, a team led by Judy Lieberman, PhD, of Boston Children's Hospital's Program in Cellular and Molecular Medicine reports "triple-negative" breast cancers may be vulnerable to drugs that attack the proteasome. This cellular structure acts as the cell's waste disposal, breaking down damaged or unneeded proteins. These cancers, which lack the three major therapeutic markers for breast cancer—the estrogen, progesterone and HER2 receptors—are very aggressive and difficult to treat. They mostly affect younger women ...

Young or old, song sparrows experience climate change differently from each other

2013-08-12
What's good for adults is not always best for the young, and vice versa. At least that is the case with song sparrows and how they experience the effects of climate change, according to two recent studies by scientists at the University of California, Davis, and Point Blue Conservation Science. Both studies show the importance of considering the various stages and ages of individuals in a species -- from babies to juveniles to adults -- to best predict not only how climate change could affect a species as a whole, but also why. "To learn how climate change is expected ...

Singapore scientists unravel cancers linked to herbal remedies

2013-08-12
Singapore, 12 August 2013 – A team of scientists from the National Cancer Centre Singapore, Duke-NUS Graduate Medical School Singapore, and Taiwan's Chang Gung Memorial Hospital, LinKou, have made a breakthrough in understanding the cancer-promoting action of Aristolochic Acid (AA), a natural product of Aristolochia plants traditionally used in some Asian herbal remedies for weight loss and slimming. Using advanced DNA sequencing technologies, the team, led by Professors Teh Bin Tean, See-Tong Pang, Patrick Tan and Steve Rozen discovered that AA is the most potent carcinogen ...

Largest study of epilepsy patients ever conducted reveals new and surprising genetic risk factors

2013-08-12
NEW YORK, August 11 – Neurologists and epilepsy researchers from NYU Langone Medical Center were among scientists who have 329 random genetic mutations associated with two of the most severe forms of epilepsy, according to a paper published today in Nature. Though well-known that many forms of epilepsy are strongly influenced by genetics, there has been relatively little progress in identifying the genetic differences that contribute to most forms of epilepsy. This study sheds light on why some with an elevated risk for epilepsy never get the disease and why certain medications ...

School lunch and TV time linked with childhood obesity

2013-08-12
The findings by the University of Michigan Frankel Cardiovascular Center will be published in the September issue of Pediatrics. While some habits were the same for all overweight and obese children, the study found some gender differences in the habits influencing body weight. Data from 1,714 sixth grade students enrolled in Project Healthy Schools showed girls who drank two servings of milk each day were less likely to be obese, and boys who played on a sports team were also at a healthier weight. "Additional work is needed to help us understand the beneficial impact ...

Physicists investigate formation of defects during phase transitions in crystals of ions

2013-08-12
Research groups at Johannes Gutenberg University Mainz (JGU) and the Physical-Technical Federal Institute (PTB) in Braunschweig, working in collaboration with scientists at the University of Ulm and The Hebrew University of Jerusalem, have been investigating the formation of defects occurring when a Coulomb crystal of ions is driven through a second-order phase transition. For this purpose, they compressed one-dimensional linear chains of ions at high speeds to form a two-dimensional zigzag structure with a form similar to that of an accordion. This process can lead to ...

Scientists have found new evidence to show how early humans migrated into Europe

2013-08-12
Humans originated in Africa. But what route did they take as they began to disperse around the world 60,000 years ago? A new professor at the University of Huddersfield has played a key role in finding the answer to one of the most fundamental questions in the history of mankind. Professor Richards, who moved to Huddersfield from the University of Leeds, is a pioneer in the field -- one of just two professors of archaeogenetics in the world. He uses DNA evidence to study human origins, comparing data from modern samples across the world and occasionally to that which ...

Young beer-drinkers binge-drink more frequently

2013-08-12
Just under a third of young Swiss men prefer beer when they drink alcohol, taking in at least two thirds of their alcohol consumption in the form of the beverage. Far fewer (around five percent) prefer wine. Is there an association between the preference for particular alcoholic beverages and a riskier approach to alcohol or other substances? This is what researchers from the Institute of Social and Preventive Medicine at the University of Zurich and Lausanne University Hospital wanted to find out by conducting a survey of around 5,400 men with an average age of 20 as part ...

Scientist names new fly species after the professor who has supported his work

2013-08-12
A Professor from The University of Manchester has had his name immortalised as a new species of fly. Professor Richard Preziosi, from the Faculty of Life Sciences, said he was delighted with the unusual tribute from researcher Dr. Dave Penney. It follows his continued support of Dr. Penney's unfunded research into amber rocks which he has been investigating for around 20 years. Dr. Penney discovered the new species of fly, which he has named Proceroplatus preziosii, on the Caribbean island of Hispaniola, after finding a fossil in 16 million-year-old amber from the ...

LAST 30 PRESS RELEASES:

When devices can read human emotions without a camera

Warming temperatures impact immune performance of wild monkeys, U-M study shows

Fine particulate air pollution may play a role in adverse birth outcomes

Sea anemone study shows how animals stay ‘in shape’

KIER unveils catalyst innovations for sustainable turquoise hydrogen solutions

Bacteria ditch tags to dodge antibiotics

New insights in plant response to high temperatures and drought

Strategies for safe and equitable access to water: a catalyst for global peace and security

CNIO opens up new research pathways against paediatric cancer Ewing sarcoma by discovering mechanisms that make it more aggressive

Disease severity staging system for NOTCH3-associated small vessel disease, including CADASIL

Satellite evidence bolsters case that climate change caused mass elephant die-off

Unique killer whale pod may have acquired special skills to hunt the world’s largest fish

Emory-led Lancet review highlights racial disparities in sudden cardiac arrest and death among athletes

A new approach to predicting malaria drug resistance

Coral adaptation unlikely to keep pace with global warming

Bioinspired droplet-based systems herald a new era in biocompatible devices

A fossil first: Scientists find 1.5-million-year-old footprints of two different species of human ancestors at same spot

The key to “climate smart” agriculture might be through its value chain

These hibernating squirrels could use a drink—but don’t feel the thirst

New footprints offer evidence of co-existing hominid species 1.5 million years ago

Moral outrage helps misinformation spread through social media

U-M, multinational team of scientists reveal structural link for initiation of protein synthesis in bacteria

New paper calls for harnessing agrifood value chains to help farmers be climate-smart

Preschool education: A key to supporting allophone children

CNIC scientists discover a key mechanism in fat cells that protects the body against energetic excess

Chemical replacement of TNT explosive more harmful to plants, study shows

Scientists reveal possible role of iron sulfides in creating life in terrestrial hot springs

Hormone therapy affects the metabolic health of transgender individuals

Survey of 12 European countries reveals the best and worst for smoke-free homes

First new treatment for asthma attacks in 50 years

[Press-News.org] Use of simple rule in children's ankle injuries reduces use of radiography by 22 percent
Low Risk Ankle Rule clinical trial