PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Women less likely to die after TAVI than men

2013-09-02
(Press-News.org) Dr Sherif said: "Earlier studies on the impact of gender on outcome after transcatheter aortic valve implantation (TAVI) have had conflicting results. A Canadian study reported in 641 consecutive patients that female sex is associated with a better long-term and short-term survival after TAVI.1 An Italian study of 305 high risk patients found no gender differences in composite safety and efficacy endpoints at 30 days and one year after TAVI."2

The current analysis examined gender differences in outcomes for 1432 consecutive patients from 27 centers who were enrolled in the German TAVI registry between January 2009 and June 2010. Women comprised 57.8% of the cohort. At baseline the average age of women was 83 years vs 80 years for men. Women had aortic valve gradients at baseline of 52 mmHg vs 45 mmHg for men (severe aortic stenosis is defined as gradients exceeding 40 mmHg).

At baseline men had more prior myocardial infarction (22% vs 11.5%, p END


ELSE PRESS RELEASES FROM THIS DATE:

TAVI feasible in bicuspid aortic valve

2013-09-02
Bicuspid aortic valve (BV) is the most common congenital valvular abnormality, occurring in 1-2% of the general population. Two of the aortic valvular leaflets fuse during development resulting in a valve that is bicuspid instead of the normal tricuspid configuration. BV is associated with increased mechanical stress which predisposes to calcification and development of aortic stenosis which narrows the opening of the aortic valve. Dr Bauer said: "TAVI is used to treat elderly high risk patients with severe aortic stenosis. Despite previous assumptions the frequency of ...

Health of older women in developed countries continues to improve

2013-09-02
Measures taken in developed countries to reduce noncommunicable diseases – the leading causes of death globally – have improved the life expectancy of women aged 50 years and older over the last 20 to 30 years. But, according to a study that will be published in the Bulletin of the World Health Organization on 2 September, the gap in life expectancy between such women in rich and poor countries is growing. The WHO study, one of a collection of articles in a special issue of the journal devoted to women's health beyond reproduction, found that the leading causes of death ...

Stomach bacteria switch off human immune defences to cause disease

2013-09-02
Helicobacter pylori is a bacterium that establishes a life-long stomach infection in humans, which in some cases can lead to duodenal ulcers or stomach cancer. New research, presented at this week's Society for General Microbiology Autumn Conference, gives us a clearer understanding of how these bacteria can manipulate the human immune system to survive in the mucosal lining of the stomach. Researchers from the University of Nottingham have shown that H. pylori is able to supress the body's normal production of 'human beta defensin 1' (hβD1), an antimicrobial factor ...

Scientists discover novel functions of platelets

2013-09-02
OKLAHOMA CITY, September 1, 2013 — A new finding could lead to novel treatments to reduce bleeding in trauma and severe infections. The research, from Oklahoma Medical Research Foundation scientists Lijun Xia, M.D., Ph.D., Jianxin Fu, M.D., Ph.D., and Brett Herzog, Ph.D., appears in the most recent issue of the journal Nature. One way the immune system keeps a body healthy is through immune surveillance. Lymphocytes, a type of white blood cell, constantly exit the bloodstream and "check in" at the lymph nodes to learn about possible pathogens or abnormal cell growth. ...

Spread of crop pests threatens global food security as Earth warms

2013-09-02
A new study has revealed that global warming is resulting in the spread of crop pests towards the North and South Poles at a rate of nearly 3 km a year. The study, published in the journal Nature Climate Change and carried out by researchers at the University of Exeter and the University of Oxford, shows a strong relationship between increased global temperatures over the past 50 years and expansion in the range of crop pests. Currently 10-16% of global crop production is lost to pests. Crop pests include fungi, bacteria, viruses, insects, nematodes, viroids and oomycetes. ...

Researchers untangle genetics of drug resistant TB

2013-09-02
For years, physicians around the world have watched as strain after strain of the deadly bacteria Mycobacterium tuberculosis evolves resistance to drugs. Over the last few decades researchers have used the tools of molecular biology to identify a handful of individual mutations that allow TB to withstand many of the key therapeutics that doctors use to treat it. These genetic markers serve as clues for new drug development and as tools for diagnosing drug-resistant strains of TB. But the pace of discovery has proven too slow in the face of the complex array of rapidly ...

Mycobacterium tuberculosis: Our African follower for over 70,000 years!

2013-09-02
Tuberculosis (TB) remains one of deadliest infectious diseases of humans, killing 50% of individuals when left untreated. Even today, TB causes 1-2 million deaths every year mainly in developing countries. Multidrug-resistance is a growing threat in the fight against the disease. An international group of researchers led by Sebastien Gagneux from the Swiss Tropical and Public Health Institute (Swiss TPH) has now identified the origin in time and space of the disease. Using whole-genome sequencing of 259 Mycobacterium tuberculosis strains collected from different parts ...

DNA 'cages' may aid drug delivery

2013-09-02
Nanoscale "cages" made from strands of DNA can encapsulate small-molecule drugs and release them in response to a specific stimulus, McGill University researchers report in a new study. The research, published online Sept. 1 in Nature Chemistry, marks a step toward the use of biological nanostructures to deliver drugs to diseased cells in patients. The findings could also open up new possibilities for designing DNA-based nanomaterials. "This research is important for drug delivery, but also for fundamental structural biology and nanotechnology," says McGill Chemistry ...

Breakthrough in sensing at the nanoscale

2013-09-02
Researchers have made a breakthrough discovery in identifying the world's most sensitive nanoparticle and measuring it from a distance using light. These super-bright, photostable and background-free nanocrystals enable a new approach to highly advanced sensing technologies using optical fibres. This discovery, by a team of researchers from Macquarie University, the University of Adelaide, and Peking University, opens the way for rapid localisation and measurement of cells within a living environment at the nanoscale, such as the changes to a single living cell in the ...

Increased greenhouse gases and aerosols have similar effects on rainfall

2013-09-02
Although greenhouse gases and aerosols have very distinct properties, their effects on spatial patterns of rainfall change are surprisingly similar, according to new research from the University of Hawaii at Manoa's International Pacific Research Center (IPRC) and Scripps Institution of Oceanography. The study is published in the September 1 online issue of Nature Geoscience. Manmade climate change comes mostly from the radiative forcing of greenhouse gases and air pollutants or aerosols. While greenhouse gases are well-mixed in the atmosphere and tend to be evenly distributed ...

LAST 30 PRESS RELEASES:

Turning herbal waste into a powerful tool for cleaning heavy metal pollution

Immune ‘peacekeepers’ teach the body which foods are safe to eat

AAN issues guidance on the use of wearable devices

In former college athletes, more concussions associated with worse brain health

Racial/ethnic disparities among people fatally shot by U.S. police vary across state lines

US gender differences in poverty rates may be associated with the varying burden of childcare

3D-printed robotic rattlesnake triggers an avoidance response in zoo animals, especially species which share their distribution with rattlers in nature

Simple ‘cocktail’ of amino acids dramatically boosts power of mRNA therapies and CRISPR gene editing

Johns Hopkins scientists engineer nanoparticles able to seek and destroy diseased immune cells

A hidden immune circuit in the uterus revealed: Findings shed light on preeclampsia and early pregnancy failure

Google Earth’ for human organs made available online

AI assistants can sway writers’ attitudes, even when they’re watching for bias

Still standing but mostly dead: Recovery of dying coral reef in Moorea stalls

3D-printed rattlesnake reveals how the rattle is a warning signal

Despite their contrasting reputations, bonobos and chimpanzees show similar levels of aggression in zoos

Unusual tumor cells may be overlooked factors in advanced breast cancer

Plants pause, play and fast forward growth depending on types of climate stress

University of Minnesota scientists reveal how deadly Marburg virus enters human cells, identify therapeutic vulnerability

Here's why seafarers have little confidence in autonomous ships

MYC amplification in metastatic prostate cancer associated with reduced tumor immunogenicity

The gut can drive age-associated memory loss

Enhancing gut-brain communication reversed cognitive decline, improved memory formation in aging mice

Mothers exposure to microbes protect their newborn babies against infection

How one flu virus can hamper the immune response to another

Researchers uncover distinct tumor “neighborhoods”, with each cell subtype playing a specific role, in aggressive childhood brain cancer

Researchers develop new way to safely insert gene-sized DNA into the genome

Astronomers capture birth of a magnetar, confirming link to some of universe’s brightest exploding stars

New photonic device, developed by MIT researchers, efficiently beams light into free space

UCSB researcher bridges the worlds of general relativity and supernova astrophysics

Global exchange of knowledge and technology to significantly advance reef restoration efforts

[Press-News.org] Women less likely to die after TAVI than men