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Latest research on ingredients that make chocolate, olive oil, tea healthful foods

2013-09-11
(Press-News.org) Contact: Michael Bernstein
m_bernstein@acs.org
317-262-5907 (Indianapolis Press Center, Sept. 6-11)
202-872-6042

Michael Woods
m_woods@acs.org
317-262-5907 (Indianapolis Press Center, Sept. 6-11)
202-872-6293 American Chemical Society
Latest research on ingredients that make chocolate, olive oil, tea healthful foods INDIANAPOLIS, Sept. 11, 2013 — The scientific spotlight focuses today on the healthful antioxidant substances in red wine, dark chocolate, olive oil, coffee, tea, and other foods and dietary supplements that are enticing millions of consumers with the promise of a healthier, longer life. The American Chemical Society, the world's largest scientific society, is holding a symposium on those substances during its 246th National Meeting & Exposition.

Reports in the symposium involve substances that consumers know best as "antioxidants," and that scientists term "phenolic derivatives." These ingredients, found naturally in certain foods and sold as dietary supplements, have been linked with health benefits that include reducing the risk of heart disease and cancer.

Entitled "Phenolic Derivatives for Food and Human Health," the symposium was held today. The meeting continues through Thursday in the Indiana Convention Center and downtown hotels. Thousands of scientists and others are expected for the meeting, which features almost 7,000 reports on new discoveries in science and other topics.

Among the topics:

The healthful effects of curcumin, found naturally in the spice, turmeric Substances in dried ginger that kill cancer cells How large intestine microbes interact with cranberry antioxidants in the diet Using biotechnology to make more effective antioxidants

Abstracts in the symposium appear below.

### A press conference on this topic will be held Tuesday, Sept. 10, at 2:30 p.m. in the ACS Press Center, Room 211 in the Indiana Convention Center. Reporters can attend in person or access live audio and video of the event and ask questions at http://www.ustream.tv/channel/acslive.

The American Chemical Society is a nonprofit organization chartered by the U.S. Congress. With more than 163,000 members, ACS is the world's largest scientific society and a global leader in providing access to chemistry-related research through its multiple databases, peer-reviewed journals and scientific conferences. Its main offices are in Washington, D.C., and Columbus, Ohio.

To automatically receive news releases from the American Chemical Society, contact newsroom@acs.org.

Note to journalists: Please report that this research was presented at a meeting of the American Chemical Society. Follow us: Twitter | Facebook

Abstracts

Antitumor activity of novel curcumin analogs in hepatocarcinoma (HepG2) cells H.P.Vasantha Rupasinghe1, vrupasinghe@dal.ca, Khushwant S. Bhullar1, Dani Youssef3, Amitabh Jha2. (1) Environmental Sciences, Dalhousie University, Truro, NS B2N 5E3, Canada, (2) Chemistry, Acadia University, Wolfwille, NS B4P 2R6, Canada, (3) Science, Université Sainte Anne, Church Point, NS B0W 1M0, Canada

Curcumin, a natural polyphenol of turmeric, continues to receive considerable attention as potent antioxidant and anti-cancer agent. Numerous analogues of curcumin have been synthesized and screened for their improved biological activities. An assessment of anticancer activities of curcumin and its novel 15 analogues was conducted in vitro. Various biochemical and toxicological techniques were employed to assess the therapeutic action of the synthetic novel curcumin analogs in comparison to curcumin and Sorafenib™ (a clinically approved drug). Inhibition of the cancer cell (HepG2) proliferation assessed by MTS assay showed that compound 2-[(E)-3-(4-hydroxyphenyl)acryloyl]-6-[1-(4-hydroxyphenyl)meth-(E)-ylidene]-cyclohexanone exhibits the trongest anticancer activity compared to curcumin and Sorafenib™ (p END


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[Press-News.org] Latest research on ingredients that make chocolate, olive oil, tea healthful foods