PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Early surgery for hip fractures in older adults may improve outcomes

Randomized controlled trial

2013-11-18
(Press-News.org) Contact information: Kim Barnhardt
kim.barnhardt@cmaj.ca
613-520-7116 x2224
Canadian Medical Association Journal
Early surgery for hip fractures in older adults may improve outcomes Randomized controlled trial Early surgery for hip fractures in older people may substantially improve outcomes for patients, according to the results from a randomized controlled trial in CMAJ (Canadian Medical Association Journal).

Hip fractures can cause serious complications that may result in death or admission to long-term care facilities for some older adults who previously lived at home. Hip fractures cause pain, bleeding and immobility, which can lead to medical complications in people awaiting surgery.

In many countries, including Canada, waits for hip surgery can be 24 hours or longer, mainly because of preoperative medical clearance procedures and operating room access. To determine whether early surgery improves outcomes for people with hip fractures, a team of Canadian researchers enrolled 60 people aged 45 years or older who were diagnosed with a hip fracture requiring surgery on a weekday during daytime working hours. The patients, from 2 hospitals in Hamilton, Ontario, Canada and 1 in Pune, India, were randomized to a group that received accelerated care (30 patients) and to a control group that received standard care (30 patients).

The mean age of participants was 81 years, and 63% were female. Many had several illnesses, of whom 68% had hypertension, 20% coronary artery disease and 17% dementia. For patients in the accelerated care group, the median time between diagnosis with fracture and clearance for surgery was 1.5 hours compared with 3.4 hours in the standard care group. The median time from diagnosis to surgery was 6 hours for the accelerated care group, more than 18 hours less than the 24.2 hours to surgery in the standard care group.

The researchers set a target of 6 hours for accelerated surgery. "We believe that the shortest time possible will provide the greatest potential for benefit, as is the case in acute myocardial infarction and stroke," states Dr. P.J. Devereaux, McMaster University, Hamilton, Ontario, Canada, co-principal investigator of the HIP ATTACK pilot trial.

"This pilot trial shows demonstrates the feasibility of a trial comparing accelerated and standard care among patients with a hip fracture," conclude the authors. "The results provide encouraging evidence that accelerated surgery may substantially improve outcomes in these patients," states Dr. Mohit Bhandari, McMaster University, co-principal investigator of the HIP ATTACK pilot trial.

The research team plans to conduct a full-scale trial in 2014 and invites interested researchers to join the trial.

### END


ELSE PRESS RELEASES FROM THIS DATE:

Blood growth factor boosts effect of exercise in peripheral artery disease

2013-11-18
Blood growth factor boosts effect of exercise in peripheral artery disease A blood cell growth factor can boost the effects of exercise in improving mobility for patients with peripheral artery disease, a clinical study has shown. The results are scheduled for ...

Greater density of coronary artery calcium associated with lower risk of CHD, CVD

2013-11-18
Greater density of coronary artery calcium associated with lower risk of CHD, CVD Chicago – Michael H. Criqui, M.D., M.P.H., of the University of California, San Diego, and colleagues determined the independent associations of coronary artery calcium (CAC) volume and ...

Type of cell therapy does not improve walking ability for patients with peripheral artery disease

2013-11-18
Type of cell therapy does not improve walking ability for patients with peripheral artery disease Chicago – Joseph Poole, M.D., Ph.D., of the Emory University School of Medicine, Atlanta, and colleagues studied whether therapy with granulocyte-macrophage ...

Therapy using stem cells, bone marrow cells, appears safe for patients with ischemic cardiomyopathy

2013-11-18
Therapy using stem cells, bone marrow cells, appears safe for patients with ischemic cardiomyopathy Chicago – Alan W. Heldman, M.D., of the University of Miami Miller School of Medicine, and colleagues conducted a study to examine the safety of transendocardial ...

Addition of certain drugs to diuretic therapy does not improve kidney function

2013-11-18
Addition of certain drugs to diuretic therapy does not improve kidney function Chicago – Horng H. Chen, M.B.B.Ch., of the Mayo Clinic, Rochester, Minn., and colleagues conducted a randomized trial to determine whether, as compared with placebo, the addition of ...

More than skin deep: New layer to the body's fight against infection

2013-11-18
More than skin deep: New layer to the body's fight against infection The layers of skin that form the first line of defence in the body's fight against infection have revealed a unanticipated secret. The single cell type that was thought to be behind ...

Bacteria use lethal cytotoxins to evade antibiotic treatment

2013-11-18
Bacteria use lethal cytotoxins to evade antibiotic treatment In spite of the fact that the first antibiotics were discovered almost a century ago, infectious diseases such as tuberculosis, encephalitis and meningitis are still serious diseases for humans in the ...

Manipulation of protein could help stop spread of cancer cells

2013-11-18
Manipulation of protein could help stop spread of cancer cells DNA regulator stops cancer cells in their tracks Understanding how and why cancer cells move away from their original location is important to find ways to stop the spread of the disease. ...

Vismodegib in basal cell carcinoma: Added benefit not proven

2013-11-18
Vismodegib in basal cell carcinoma: Added benefit not proven Hardly any patient-relevant outcomes were investigated/ studies without control groups The drug vismodegib (trade name: Erivedge) is approved for the treatment of patients ...

Amber provides new insights into the evolution of the Earth's atmosphere

2013-11-18
Amber provides new insights into the evolution of the Earth's atmosphere Scientists encounter big challenges when reconstructing atmospheric compositions in the Earth's geological past because of the lack of useable sample material. One of the few ...

LAST 30 PRESS RELEASES:

Fame itself may be critical factor in shortening singers’ lives

Daily coffee drinking may slow biological ageing of people with major mental illness

New highly efficient material turns motion into power – without toxic lead

The DEVILS in the details: New research reveals how the cosmic landscape impacts the galaxy lifecycle

After nearly 100 years, scientists may have detected dark matter

Gender imbalance hinders equitable environmental governance, say UN scientists

Six University of Tennessee faculty among world’s most highly cited researchers

A type of immune cell could hold a key to preventing scar tissue buildup in wounds

Mountains as water towers: New research highlights warming differences between high and low elevations

University of Tennessee secures $1 million NSF grant to build semiconductor workforce pipeline

Biochar shows powerful potential to build cleaner and more sustainable cities worldwide

UT Health San Antonio leads $4 million study on glucagon hormone’s role in diabetes, obesity

65-year-old framework challenged by modern research

AI tool helps visually impaired users ‘feel’ where objects are in real time

Collaborating minds think alike, processing information in similar ways in a shared task

Routine first trimester ultrasounds lead to earlier detection of fetal anomalies

Royal recognition for university’s dementia work

It’s a bird, it’s a drone, it’s both: AI tech monitors turkey behavior

Bormioli Luigi renews LionGlass deal with Penn State after successful trial run

Are developers prepared to control super-intelligent AI?

A step toward practical photonic quantum neural networks

Study identifies target for disease hyper progression after immunotherapy in kidney cancer

Concordia researchers identify key marker linking coronary artery disease to cognitive decline

HER2-targeted therapy shows promising results in rare bile duct cancers

Metabolic roots of memory loss

Clinical outcomes and in-hospital mortality rate following heart valve replacements at a tertiary-care hospital

Too sick to socialize: How the brain and immune system promote staying in bed

Seal milk more refined than breast milk

Veterans with cardiometabolic conditions face significant risk of dying during extreme heat events

How plants search for nutrients

[Press-News.org] Early surgery for hip fractures in older adults may improve outcomes
Randomized controlled trial