PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Early surgery for hip fractures in older adults may improve outcomes

Randomized controlled trial

2013-11-18
(Press-News.org) Contact information: Kim Barnhardt
kim.barnhardt@cmaj.ca
613-520-7116 x2224
Canadian Medical Association Journal
Early surgery for hip fractures in older adults may improve outcomes Randomized controlled trial Early surgery for hip fractures in older people may substantially improve outcomes for patients, according to the results from a randomized controlled trial in CMAJ (Canadian Medical Association Journal).

Hip fractures can cause serious complications that may result in death or admission to long-term care facilities for some older adults who previously lived at home. Hip fractures cause pain, bleeding and immobility, which can lead to medical complications in people awaiting surgery.

In many countries, including Canada, waits for hip surgery can be 24 hours or longer, mainly because of preoperative medical clearance procedures and operating room access. To determine whether early surgery improves outcomes for people with hip fractures, a team of Canadian researchers enrolled 60 people aged 45 years or older who were diagnosed with a hip fracture requiring surgery on a weekday during daytime working hours. The patients, from 2 hospitals in Hamilton, Ontario, Canada and 1 in Pune, India, were randomized to a group that received accelerated care (30 patients) and to a control group that received standard care (30 patients).

The mean age of participants was 81 years, and 63% were female. Many had several illnesses, of whom 68% had hypertension, 20% coronary artery disease and 17% dementia. For patients in the accelerated care group, the median time between diagnosis with fracture and clearance for surgery was 1.5 hours compared with 3.4 hours in the standard care group. The median time from diagnosis to surgery was 6 hours for the accelerated care group, more than 18 hours less than the 24.2 hours to surgery in the standard care group.

The researchers set a target of 6 hours for accelerated surgery. "We believe that the shortest time possible will provide the greatest potential for benefit, as is the case in acute myocardial infarction and stroke," states Dr. P.J. Devereaux, McMaster University, Hamilton, Ontario, Canada, co-principal investigator of the HIP ATTACK pilot trial.

"This pilot trial shows demonstrates the feasibility of a trial comparing accelerated and standard care among patients with a hip fracture," conclude the authors. "The results provide encouraging evidence that accelerated surgery may substantially improve outcomes in these patients," states Dr. Mohit Bhandari, McMaster University, co-principal investigator of the HIP ATTACK pilot trial.

The research team plans to conduct a full-scale trial in 2014 and invites interested researchers to join the trial.

### END


ELSE PRESS RELEASES FROM THIS DATE:

Blood growth factor boosts effect of exercise in peripheral artery disease

2013-11-18
Blood growth factor boosts effect of exercise in peripheral artery disease A blood cell growth factor can boost the effects of exercise in improving mobility for patients with peripheral artery disease, a clinical study has shown. The results are scheduled for ...

Greater density of coronary artery calcium associated with lower risk of CHD, CVD

2013-11-18
Greater density of coronary artery calcium associated with lower risk of CHD, CVD Chicago – Michael H. Criqui, M.D., M.P.H., of the University of California, San Diego, and colleagues determined the independent associations of coronary artery calcium (CAC) volume and ...

Type of cell therapy does not improve walking ability for patients with peripheral artery disease

2013-11-18
Type of cell therapy does not improve walking ability for patients with peripheral artery disease Chicago – Joseph Poole, M.D., Ph.D., of the Emory University School of Medicine, Atlanta, and colleagues studied whether therapy with granulocyte-macrophage ...

Therapy using stem cells, bone marrow cells, appears safe for patients with ischemic cardiomyopathy

2013-11-18
Therapy using stem cells, bone marrow cells, appears safe for patients with ischemic cardiomyopathy Chicago – Alan W. Heldman, M.D., of the University of Miami Miller School of Medicine, and colleagues conducted a study to examine the safety of transendocardial ...

Addition of certain drugs to diuretic therapy does not improve kidney function

2013-11-18
Addition of certain drugs to diuretic therapy does not improve kidney function Chicago – Horng H. Chen, M.B.B.Ch., of the Mayo Clinic, Rochester, Minn., and colleagues conducted a randomized trial to determine whether, as compared with placebo, the addition of ...

More than skin deep: New layer to the body's fight against infection

2013-11-18
More than skin deep: New layer to the body's fight against infection The layers of skin that form the first line of defence in the body's fight against infection have revealed a unanticipated secret. The single cell type that was thought to be behind ...

Bacteria use lethal cytotoxins to evade antibiotic treatment

2013-11-18
Bacteria use lethal cytotoxins to evade antibiotic treatment In spite of the fact that the first antibiotics were discovered almost a century ago, infectious diseases such as tuberculosis, encephalitis and meningitis are still serious diseases for humans in the ...

Manipulation of protein could help stop spread of cancer cells

2013-11-18
Manipulation of protein could help stop spread of cancer cells DNA regulator stops cancer cells in their tracks Understanding how and why cancer cells move away from their original location is important to find ways to stop the spread of the disease. ...

Vismodegib in basal cell carcinoma: Added benefit not proven

2013-11-18
Vismodegib in basal cell carcinoma: Added benefit not proven Hardly any patient-relevant outcomes were investigated/ studies without control groups The drug vismodegib (trade name: Erivedge) is approved for the treatment of patients ...

Amber provides new insights into the evolution of the Earth's atmosphere

2013-11-18
Amber provides new insights into the evolution of the Earth's atmosphere Scientists encounter big challenges when reconstructing atmospheric compositions in the Earth's geological past because of the lack of useable sample material. One of the few ...

LAST 30 PRESS RELEASES:

UMass Amherst Nursing Professor Emerita honored as ‘Living Legend’

New guidelines aim to improve cystic fibrosis screening

Picky eaters by day, buffet by night: Butterfly, moth diets sync to plant aromas

Pennington Biomedical’s Dr. Leanne Redman honored with the E. V. McCollum Award from the American Society for Nutrition

CCNY physicists uncover electronic interactions mediated via spin waves

Researchers’ 3D-printing formula may transform future of foam

Nurture more important than nature for robotic hand

Drug-delivering aptamers target leukemia stem cells for one-two knockout punch

New study finds that over 95% of sponsored influencer posts on Twitter were not disclosed

New sea grant report helps great lakes fish farmers navigate aquaculture regulations

Strain “trick” improves perovskite solar cells’ efficiency

How GPS helps older drivers stay on the roads

Estrogen and progesterone stimulate the body to make opioids

Dancing with the cells – how acoustically levitating a diamond led to a breakthrough in biotech automation

Machine learning helps construct an evolutionary timeline of bacteria

Cellular regulator of mRNA vaccine revealed... offering new therapeutic options

Animal behavioral diversity at risk in the face of declining biodiversity

Finding their way: GPS ignites independence in older adult drivers

Antibiotic resistance among key bacterial species plateaus over time

‘Some insects are declining but what’s happening to the other 99%?’

Powerful new software platform could reshape biomedical research by making data analysis more accessible

Revealing capillaries and cells in living organs with ultrasound

American College of Physicians awards $260,000 in grants to address equity challenges in obesity care

Researchers from MARE ULisboa discover that the European catfish, an invasive species in Portugal, has a prolonged breeding season, enhancing its invasive potential

Rakesh K. Jain, PhD, FAACR, honored with the 2025 AACR Award for Lifetime Achievement in Cancer Research

Solar cells made of moon dust could power future space exploration

Deporting immigrants may further shrink the health care workforce

Border region emergency medical services in migrant emergency care

Resident physician intentions regarding unionization

Healthy nutrition and physical lifestyle choices lower cancer mortality risk for survivors, new ACS study finds

[Press-News.org] Early surgery for hip fractures in older adults may improve outcomes
Randomized controlled trial