PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Multi-component therapy shown beneficial in treating PTSD in adolescent girls

2013-12-27
(Press-News.org) Contact information: Steve Graff
Stephen.Graff@uphs.upenn.edu
215-349-5653
The JAMA Network Journals
Multi-component therapy shown beneficial in treating PTSD in adolescent girls Adolescents girls with sexual abuse-related posttraumatic stress disorder (PTSD) experienced greater benefit from prolonged exposure therapy (a type of therapy that has been shown effectiveness for adults) than from supportive counseling, according to a study appearing in the December 25 issue of JAMA.

"Adolescence is a unique developmental stage that is associated with increased exposure to traumatic events that can lead to PTSD," according to background information in the article. "Prolonged exposure therapy is the most studied evidence-based, theory-driven treatment for adults with PTSD, but it is rarely provided to adolescents because of concern that it may exacerbate PTSD symptoms or the belief that patients must master coping skills before exposure can safely be provided." Prolonged exposure therapy is a form of behavior therapy and cognitive behavioral therapy, characterized by re-experiencing the traumatic event through remembering it and engaging with, rather than avoiding, reminders of the trauma (triggers).

Edna B. Foa, Ph.D., of the University of Pennsylvania, Philadelphia, and colleagues hypothesized that a prolonged exposure program modified for adolescents (prolonged exposure-A) would be superior to supportive counseling in reducing interviewer-assessed PTSD severity, rate of PTSD diagnosis, self-reported PTSD severity and depression, and improving general functioning. The trial included 61 adolescent girls with PTSD; counselors who had not previously administered prolonged exposure therapy provided the treatments in a community mental health clinic. Participants were randomized to receive fourteen 60- to 90-minute sessions of prolonged exposure therapy (n = 31) or supportive counseling (n = 30). Follow-up was 12 months.

Participants who received prolonged exposure showed greater improvement in PTSD symptoms and were more likely to lose their PTSD diagnosis and be classified as good responders than those who received supportive counseling. Also, participants who received prolonged exposure demonstrated greater improvement in depressive symptoms and functioning than those who received supportive counseling. The superiority of prolonged exposure over supportive counseling was also evident at 12-month follow-up.

"An important clinical implication of these results is the feasibility of disseminating and implementing prolonged exposure-A in community mental health clinics for adolescents who are motivated to participate in treatment. Prolonged exposure-A was successfully implemented by counselors with no prior training in evidence-based treatments and with relatively little supervision from experts. This is important because the need for evidence-based treatment of PTSD far exceeds the availability of these services," the authors write.

(doi:10.l001/jama.2013.282829; Available pre-embargo to the media at http://media.jamanetwork.com)

Editor's Note: This study was conducted with support from the National Institute of Mental Health awarded to Dr. Foa. Please see the article for additional information, including other authors, author contributions and affiliations, financial disclosures, etc.

Editorial: Prolonged Exposure Therapy for PTSD in Sexually Abused Adolescents

Sean Perrin, Ph.D., of Lund University, Lund, Sweden, comments on the findings of this study in an accompanying editorial.

"Findings from the current report by Foa et al should allay therapist concerns about any potential harmful effects of exposure and the need for extensive preparation of the patient for exposure. The heightened arousal that accompanies exposure to traumatic reminders in session usually dissipates within a few sessions and leads to rapid reductions in symptoms between sessions. Thus, the heightened arousal that many therapists fear causing by leading the patients through exposure exercises is an expected and integral part of the recovery progress."

"In the future, greater efforts are needed to increase awareness about the safety, tolerability, and effectiveness of treatments like prolonged exposure. Research is also needed to determine the minimum amount of training and supervision for therapists to effectively deliver prolonged exposure and similar exposure-focused treatments to patients with PTSD and other anxiety disorders."

(doi:10.l001/jama.2013.283944; Available pre-embargo to the media at http://media.jamanetwork.com)

Editor's Note: The author has completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest and none were reported.

###

END



ELSE PRESS RELEASES FROM THIS DATE:

Adding cognitive behavioral therapy to treatment of pediatric migraine improves relief of symptoms

2013-12-27
Adding cognitive behavioral therapy to treatment of pediatric migraine improves relief of symptoms Among children and adolescents with chronic migraine, the use of cognitive behavioral therapy (CBT) resulted in greater reductions in headache frequency and migraine-related ...

Proportion of opioid treatment programs offering on-site testing for HIV and STIs declines

2013-12-27
Proportion of opioid treatment programs offering on-site testing for HIV and STIs declines A survey of opioid treatment programs finds that the proportion offering on-site testing for human immunodeficiency virus (HIV) and sexually transmitted infections ...

Use of antidepressant does not improve symptoms from stomach disorder

2013-12-27
Use of antidepressant does not improve symptoms from stomach disorder Among patients with idiopathic (of unknown cause) gastroparesis, use of the antidepressant nortriptyline compared with placebo for 15 weeks did not result in improvement in overall ...

Nonsteroidal anti-inflammatory agent slows rate of progression of neurodegenerative disease

2013-12-27
Nonsteroidal anti-inflammatory agent slows rate of progression of neurodegenerative disease Among patients with familial amyloid polyneuropathy, a lethal, genetic neurodegenerative disease, use of the nonsteroidal anti-inflammatory agent diflunisal compared ...

Prolonged exposure therapy found beneficial in treating adolescent girls with PTSD

2013-12-27
Prolonged exposure therapy found beneficial in treating adolescent girls with PTSD (PHILADELPHIA) – Researchers at Penn Medicine report in the December 25 issue of JAMA that a modified form of prolonged exposure therapy ...

Antidepressants for bipolar disorder

2013-12-27
Antidepressants for bipolar disorder The use of antidepressants in the treatment of bipolar disorder remains controversial. Some studies and treatment guidelines suggest that antidepressant treatment for bipolar disorder may have the potential to increase the manic ...

NASA sees the last of Cyclone Bruce in Southern Indian Ocean

2013-12-27
NASA sees the last of Cyclone Bruce in Southern Indian Ocean Tropical Cyclone Bruce is winding down in the Southern Indian Ocean as wind shear and cooler waters affect the storm. NASA's Aqua satellite flew over Bruce on December 24 and showed that wind shear is having ...

Kinect-based virtual reality training promotes brain reorganization after stroke

2013-12-27
Kinect-based virtual reality training promotes brain reorganization after stroke The Kinect-based virtual reality system for the Xbox 360 enables users to control and interact with the game console without the need to touch a game controller, and provides rehabilitation ...

Activating P300 protein contributes to repair of hippocampal neuronal DNA injuries

2013-12-27
Activating P300 protein contributes to repair of hippocampal neuronal DNA injuries Various medications have been developed to treat neurodegenerative disorders, and drugs without significant side effects are gaining widespread interest such disorders. Brain Research ...

Epigenetics enigma resolved

2013-12-27
Epigenetics enigma resolved First structure of enzyme that removes methylation Scientists have obtained the first detailed molecular structure of a member of the Tet family of enzymes. The finding is important for the field of epigenetics because Tet enzymes chemically ...

LAST 30 PRESS RELEASES:

'One child called the robot "my little brother"': Can assistance tech become part of the family?

Small but mighty: A biomimetic idea takes flight

New hydrogel-based treatment accelerates infected wound healing and balances skin microbiota

New bioactive dressing promises faster diabetic wound healing

Japan launches fully domestically produced quantum computer

Home is where the airfields are: What happens when hawks are moved from Los Angeles airports

Study: Sylvester researchers uncover molecular drivers of cellular differentiation

Withdrawal of kidney treatment significantly benefits patients and NHS

Illinois Tech hosts EV Readiness Community Awards, showcasing nation-leading energy innovation

Rice bioscientist wins NSF CAREER Award to investigate bacterial toxins, expand inclusion in STEM

Study links exercise with decreased mortality and cardiovascular events in people recently diagnosed with type 2 diabetes but no previous cardiovascular disease

Genetic testing reduces risks from chemotherapy for gastrointestinal cancer patients

UVic research predicts worldwide glacier erosion

A new boost for CryoZoo, Barcelona’s animal cell biobank

Asthma drug Zileuton blocks food allergy reactions in mice

Molecules in the spotlight: Snapshots reveal the eternal dance of particles

What drives anaphylactic response in food allergies

A thoughtful approach to governing emerging quantum technologies

What makes the teeth of chitons iron hard?

New antibody targeting approach, tested in mice, improves distribution and safety of Alzheimer’s immunotherapies

UC Irvine scientist takes a lesson from ultrahard, wear-resistant mollusk teeth

ICFO researchers overcome long-standing bottleneck in single photon detection with twisted 2D materials

New scaffold technology helps combat traumatic brain injury by restoring copper balance

Bone metastases cultivate immature immune cells to resist immunotherapy

Liming can help enhance carbon capture in agricultural fields

National study urges expanded vaccine screening in emergency departments

Simple color-changing sensor quickly identifies poisonous gases

Exosomes found to play a double role in tumor growth and immune response

Announcing Gordian Biotechnology as Tier 5 Sponsor of ARDD 2025

Disconnection between brain regions explains why some people don’t enjoy music

[Press-News.org] Multi-component therapy shown beneficial in treating PTSD in adolescent girls