PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Nano-capsules show potential for more potent chemoprevention

2014-01-08
(Press-News.org) Contact information: Judy Fortin
judy.fortin@emory.edu
404-778-4580
Emory Health Sciences
Nano-capsules show potential for more potent chemoprevention Researchers at the Winship Cancer Institute of Emory University have discovered a more effective drug delivery system using nanotechnology that could one day significantly affect cancer prevention.

The study, published today in Cancer Prevention Research, a journal of the American Association for Cancer Research, involved the use of microscopic amounts of the naturally occurring antioxidant, luteolin, that were encapsulated in a water-soluble polymer. When injected into mice the nano-luteolin inhibited growth of lung cancer and head and neck cancer cells.

"Our results suggest that nanoparticle delivery of naturally occurring dietary agents like luteolin has many advantages," says senior study author Dong Moon Shin, MD, professor of hematology and medical oncology at Emory University School of Medicine and associate director of academic development at Winship Cancer Institute. "By using a high concentration of luteolin in the blood, we were better able to inhibit the growth of cancer cells."

Luteolin is known for its anti-inflammatory and anti-cancer effects. It is naturally found in green vegetables such as broccoli, celery and artichokes, however, Shin says large quantities would need to be consumed to be effective. By concentrating the compound into a nanoparticle and making it easy to dissolve in water, researchers conclude nano-luteolin has immense potential for future human studies of chemoprevention

Chemoprevention is currently used to help stop the recurrence of cancer in patients and reduce the risk of cancer in others.

### Winship Cancer Institute of Emory University is Georgia's only National Cancer Institute-Designated Cancer Center and serves as the coordinating center for cancer research and care throughout Emory University. For over 75 years, Winship has served the citizens of Georgia and the Southeast by working tirelessly to prevent, treat and cure cancer.

To learn more about the Winship Cancer Institute of Emory University, its research, outreach, clinical trials and faculty and staff, visit http://winshipcancer.emory.edu.


ELSE PRESS RELEASES FROM THIS DATE:

Nutrition guidelines needed for full-service restaurant chains

2014-01-08
Nutrition guidelines needed for full-service restaurant chains According to a new study in the Journal of Nutrition Education and Behavior Philadelphia, PA, January 8, 2014 – Food prepared away from home is typically higher in calories and lower in nutrition than ...

Reactivation of the AKT survival pathway by ERK1/2

2014-01-07
Reactivation of the AKT survival pathway by ERK1/2 Why inhibition of both pathways is important In the study by Toulany et al., it was demonstrated for the first time that long term treatment with inhibitors of PI3K (as it is performed clinically) results in a reactivation ...

Inverse design: New route to design a practical invisibility cloak

2014-01-07
Inverse design: New route to design a practical invisibility cloak With the emergence of metamaterials and transformation optics in the past few years, invisibility has become a scientific possibility that has attracted sustainable research interest. Recently, a review ...

Jumping snails left grounded in future oceans

2014-01-07
Jumping snails left grounded in future oceans Sea snails that leap to escape their predators may soon lose their extraordinary jumping ability because of rising human carbon dioxide emissions, a team of international scientists ...

Nanoplasmonics: Towards efficient light harvesting

2014-01-07
Nanoplasmonics: Towards efficient light harvesting The control of light is vital to many applications, including imaging, communications, sensing, cancer treatment, and even welding processes for automobile parts. Transformation optics is an emerging field that has revolutionized ...

Cancer Statistics 2014: Death rates continue to drop

2014-01-07
Cancer Statistics 2014: Death rates continue to drop Progress most rapid for middle-aged African American men ATLANTA – Jan. 7, 2014–The annual cancer statistics report from the American Cancer Society finds steady declines in cancer death rates for the past two decades ...

Researchers discover molecule behind the benefits of exercise

2014-01-07
Researchers discover molecule behind the benefits of exercise While it's clear that exercise can improve health and longevity, the changes that occur in the body to facilitate these benefits are less clear. Now researchers publishing in the January issue of Cell Press journal ...

How fat might be controlled through the body clock

2014-01-07
How fat might be controlled through the body clock Australian researchers have shed more light on an underexplored aspect of the important brain-signaling system that controls appetite, body composition and energy use. Their findings suggest ...

Ketamine acts as antidepressant by boosting serotonin

2014-01-07
Ketamine acts as antidepressant by boosting serotonin PET molecular imaging of the brain reveals that ketamine may act as an antidepressant by boosting serotonin activity in brain areas involved in motivation Ketamine is a potent anesthetic employed in human and veterinary medicine, ...

U of Maryland undergraduates discover rare eclipsing double asteroid

2014-01-07
U of Maryland undergraduates discover rare eclipsing double asteroid Fewer than 100 such asteroids have been found in main asteroid belt COLLEGE PARK, MD – Students in a University of Maryland undergraduate astronomy class have made a rare discovery that wowed professional ...

LAST 30 PRESS RELEASES:

Exercise as an anti-ageing intervention to avoid detrimental impact of mental fatigue

UMass Amherst Nursing Professor Emerita honored as ‘Living Legend’

New guidelines aim to improve cystic fibrosis screening

Picky eaters by day, buffet by night: Butterfly, moth diets sync to plant aromas

Pennington Biomedical’s Dr. Leanne Redman honored with the E. V. McCollum Award from the American Society for Nutrition

CCNY physicists uncover electronic interactions mediated via spin waves

Researchers’ 3D-printing formula may transform future of foam

Nurture more important than nature for robotic hand

Drug-delivering aptamers target leukemia stem cells for one-two knockout punch

New study finds that over 95% of sponsored influencer posts on Twitter were not disclosed

New sea grant report helps great lakes fish farmers navigate aquaculture regulations

Strain “trick” improves perovskite solar cells’ efficiency

How GPS helps older drivers stay on the roads

Estrogen and progesterone stimulate the body to make opioids

Dancing with the cells – how acoustically levitating a diamond led to a breakthrough in biotech automation

Machine learning helps construct an evolutionary timeline of bacteria

Cellular regulator of mRNA vaccine revealed... offering new therapeutic options

Animal behavioral diversity at risk in the face of declining biodiversity

Finding their way: GPS ignites independence in older adult drivers

Antibiotic resistance among key bacterial species plateaus over time

‘Some insects are declining but what’s happening to the other 99%?’

Powerful new software platform could reshape biomedical research by making data analysis more accessible

Revealing capillaries and cells in living organs with ultrasound

American College of Physicians awards $260,000 in grants to address equity challenges in obesity care

Researchers from MARE ULisboa discover that the European catfish, an invasive species in Portugal, has a prolonged breeding season, enhancing its invasive potential

Rakesh K. Jain, PhD, FAACR, honored with the 2025 AACR Award for Lifetime Achievement in Cancer Research

Solar cells made of moon dust could power future space exploration

Deporting immigrants may further shrink the health care workforce

Border region emergency medical services in migrant emergency care

Resident physician intentions regarding unionization

[Press-News.org] Nano-capsules show potential for more potent chemoprevention