(Press-News.org) Contact information: Alison Barbuti
alison.barbuti@manchester.ac.uk
44-016-127-58383
University of Manchester
Cause identified for children and adults with joint, skeletal and skin problems
Scientists from the University of Manchester and Central Manchester University Hospitals NHS Foundation Trust have identified the cause of a rare condition called Leri's pleonosteosis
Scientists from The University of Manchester and Central Manchester University Hospitals NHS Foundation Trust have identified the cause of a rare condition called Leri's pleonosteosis (LP).
Dr Sid Banka from the Manchester Centre for Genomic Medicine at The University of Manchester, led a team of researchers on the study which was published in Annals of Rheumatic Diseases journal Jan. 18, 2014.
LP is an inherited condition in which children are born with contractures of multiple joints and then develop difficulty of joint movements that progress in severity with age. The research team showed that extra genetic material on chromosome number 8 caused the condition in two families from Manchester.
Some patients with LP also develop thickening of their skin, similar to that seen in patients with a more common disorder called scleroderma.
Using their new knowledge, the research team showed that the genetic cause of LP is linked to whether people get scleroderma or not.
This work opens opportunities to understand scleroderma and explore new treatments.
### END
Cause identified for children and adults with joint, skeletal and skin problems
Scientists from the University of Manchester and Central Manchester University Hospitals NHS Foundation Trust have identified the cause of a rare condition called Leri's pleonosteosis
2014-01-24
ELSE PRESS RELEASES FROM THIS DATE:
Study expands the cancer genomics universe
2014-01-24
A landmark study across many cancer types reveals that the universe of cancer mutations is much bigger than ...
Omnibus appropriations bill signed into law
2014-01-24
The Academy of Radiology Research thanks Congress and the President for their support of the omnibus appropriations bill. ...
Psychologists document the age our earliest memories fade
2014-01-24
Although infants use their memories to learn new information, few adults can remember events in their lives that happened prior to ...
Integrating vegetation into sustainable transportation planning may benefit public health
2014-01-24
SACRAMENTO, Calif.—Strategic placement of trees and plants near busy roadways may enhance air quality and positively impact ...
The rocky road to a better flu vaccine
2014-01-24
Currently approved flu vaccines are less effective in the elderly, yet an estimated 90% of influenza-related deaths occur in people over 65. A paper published on January 23rd in PLOS Pathogens reports on the challenges scientists ...
Sickle cell trait in African-American dialysis patients affects dosing of anemia drugs
2014-01-24
Washington, DC (January 23, 2014) — The presence of sickle cell trait among African Americans may help explain why those ...
The evolution of drug resistance within a HIV population
2014-01-24
Drug resistance mutations in HIV reduce the genetic diversity in the rest of the virus genome when they spread within an infected patient, but they do so to a different extent in different patients. A new study ...
Stanford scientists use 'virtual earthquakes' to forecast Los Angeles quake risk
2014-01-24
Stanford scientists are using weak vibrations generated by the Earth's oceans to produce "virtual earthquakes" that can be used to predict the ground movement and shaking hazard to buildings ...
Can walkies tell who's the leader of the pack?
2014-01-24
PUBLIC RELEASE DATE: 23-Jan-2014
[
| E-mail
]
var addthis_pub="eurekalert"; var addthis_options = "favorites, delicious, digg, facebook, twitter, google, newsvine, reddit, slashdot, stumbleupon, buzz, more"
Share
Contact: Oxford University News & Information Office
press.office@admin.ox.ac.uk
01-865-280-532
University of Oxford
Can walkies tell who's the leader of the pack?
Dogs' paths during group walks could be used to determine leadership roles, social ranks and personality traits
...
Small size in early pregnancy linked to poor heart health later in life
2014-01-24
Poor growth in the first three months of pregnancy ...
LAST 30 PRESS RELEASES:
Youngest in class at higher risk of mental health problems
American Heart Association announces new volunteer leaders for 2025-26
Gut microbiota analysis can help catch gestational diabetes
FAU’s Paulina DeVito awarded prestigious NSF Graduate Research Fellowship
Champions for change – Paid time off initiative just made clinical trials participation easier
Fentanyl detection through packaging
Prof. Eran Meshorer elected to EMBO for pioneering work in epigenetics
New 3D glacier visualizations provide insights into a hotter Earth
Creativity across disciplines
Consequences of low Antarctic sea ice
Hear here: How loudness and acoustic cues help us judge where a speaker is facing
A unique method of rare-earth recycling can strengthen the raw material independence of Europe and America
Epilepsy self-management program shows promise to control seizures, improve mood and quality of life
Fat may play an important role in brain metabolism
New study finds no lasting impact of pandemic pet ownership on human well-being
New insights on genetic damage of some chemotherapies could guide future treatments with less harmful side effects
Gut microbes could protect us from toxic ‘forever chemicals’
Novel modelling links sea ice loss to Antarctic ice shelf calving events
Scientists can tell how fast you're aging from a single brain scan
U.S. uterine cancer incidence and mortality rates expected to significantly increase by 2050
Public take the lead in discovery of new exploding star
What are they vaping? Study reveals alarming surge in adolescent vaping of THC, CBD, and synthetic cannabinoids
ECMWF - delivering forecasts over 10 times faster and cutting energy usage by 1000
Brazilian neuroscientist reveals how viral infections transform the brain through microscopic detective work
Turning social fragmentation into action through discovering relatedness
Cheese may really be giving you nightmares, scientists find
Study reveals most common medical emergencies in schools
Breathable yet protective: Next-gen medical textiles with micro/nano networks
Frequency-engineered MXene supercapacitors enable efficient pulse charging in TENG–SC hybrid systems
Developed an AI-based classification system for facial pigmented lesions
[Press-News.org] Cause identified for children and adults with joint, skeletal and skin problemsScientists from the University of Manchester and Central Manchester University Hospitals NHS Foundation Trust have identified the cause of a rare condition called Leri's pleonosteosis