(Press-News.org) NEW ORLEANS─The number of total knee replacement (TKR) procedures continues to climb, as does the number of revision total knee replacement (RTKR) surgeries. In the study, "The Epidemiology of Revision Total Knee Arthroplasty in the United States," presented today at the 2014 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS), researchers used the Nationwide Inpatient Sample (NIS) to evaluate the cause of knee failure for 301,718 revision RTKR surgeries performed between 2005 and 2010.
Revision surgeries were more common in women (58 percent) and most often performed in patients, ages 65 to 74. A moderate severity of illness score (related to patient comorbid illness) was identified in more than 60 percent of patients. Infection in the prosthetic knee joint (periprosthetic joint infection) was the most common reason for revision (25 percent of patients), and mechanical loosening was the cause in 18.5 percent of patients. Revision TKR procedures were more commonly performed in large, urban non-teaching hospitals in the Southern and Midwestern regions of the United States. Revisions due to periprosthetic fractures were associated with the longest length of hospital stay (up to seven days), with an average hospitalization cost of $35,000.
Elderly and female patients with a moderate number of comorbidities represented the largest proportion of the revision population. The authors suggest that optimizing patient health before surgery and paying meticulous attention to efforts by the surgical team to minimize the risk of periprosthetic joint infection may decrease the number of knee replacement revisions.
INFORMATION: END
Infection is the leading cause of failed prosthetic knee joints
Optimizing patient health before surgery may reduce need for revisions
2014-03-12
ELSE PRESS RELEASES FROM THIS DATE:
Theoretical analysis of patterns formed on the ancient Damascus blades
2014-03-12
Blacksmiths and metallurgists in the West have been puzzled for centuries as to how the unique patterns on the famous Damascus steel blades were formed. Different mechanisms for the formation of the patterns and many methods for making the swords have been suggested and attempted, but none has produced blades with patterns matching those of the Damascus swords in the museums. The debate over the mechanism of formation of the Damascus patterns is still ongoing today. Using modern metallurgical computational software (Thermo-Calc, Stockholm, Sweden), Professor Haiwen Luo ...
Liver transplant may arrest neurological damage in a rare and progressive form of autism
2014-03-12
A patient with a rare metabolic disease that causes liver failure and autistic behavior experienced significant improvements in both her physical and mental health after receiving a liver transplant, according to a new case report published in the American Journal of Transplantation. The report's findings suggest an unexpected link between metabolic conditions and some forms of autism, and they point to the importance of a healthy liver for normal brain function.
Lathosterolosis, a rare disease caused by a defect in cholesterol synthesis, is characterized by multiple congenital ...
Dingo poisoning should be stopped to protect native Australian mammals
2014-03-12
Poisoning of dingoes - the top predators in the Australian bush - has a deleterious effect on small native mammals such as marsupial mice, bandicoots and native rodents, a UNSW-led study shows.
The research, in forested National Parks in NSW, found that loss of dingoes after baiting is associated with greater activity by foxes, which prey on small marsupials and native rodents.
As well, the number of kangaroos and wallabies increases when dingoes, also known as wild dogs, disappear. Grazing by these herbivores reduces the density of the understorey vegetation in which ...
New prognostic test for breast cancer could improve patient treatment
2014-03-12
A study by researchers in Nottingham has developed a new clinical test for breast cancer which aims to improve patient treatment.
The Nottingham Prognostic Index Plus (NPI+) could be available to patients within two years.
The findings, published in the British Journal of Cancer today, could significantly improve the way in which breast cancer patients are treated by giving clinicians more detailed information about a patient's breast cancer type and its likely behaviour, which will help them create a more personalised treatment plan.
The research, funded by the Medical ...
The first food web inside humans suggests potential new treatments for infection
2014-03-12
Imagine going to the doctor with an infection and being sent home with a course of drugs. Unknown to your doctor you actually have two infections. If you take the drugs will the other infection go away by itself? What if you take the drugs and the other infection gets worse? This quandary faces those treating patients with multiple infections.
A new study led by former University of Sheffield PhD student Dr Emily Griffiths, in collaboration with the universities of Edinburgh, Liverpool and Zürich, has taken a novel approach to understanding this problem, shedding light ...
Experts urge Chancellor to 'crack down on cheap drink' in next week's budget
2014-03-12
Writing on bmj.com, Katherine Brown, Director at the Institute of Alcohol Studies, says the UK chancellor should resist industry lobbying to scrap the annual rise in alcohol duty because "society simply can't afford for such cheap drink to get cheaper."
The duty escalator has been in place since 2008 to ensure that the price of alcohol rises at 2% above inflation. But a campaign by the wine and spirits industry is calling on the Chancellor to "Be Fair George!" and scrap the duty escalator for all alcohol in this year's budget.
Last year, following a similar campaign ...
Nicotine patches do not appear to help pregnant smokers to quit
2014-03-12
Smoking during pregnancy increases the risk of adverse pregnancy and birth outcomes and may have long lasting effects in offspring.
In England, 26% of women smoke in the year before their pregnancy and 12% smoke through to delivery. The rate is similar or even higher in other high income countries.
Guidelines suggest adding nicotine replacement therapies (NRT) to behavioural smoking cessation support in pregnant smokers because of their excellent safety profile and proved effectiveness in other groups of smokers. However, there is a lack of good quality evidence on ...
Community action not enough to reduce problem drinking and related harms
2014-03-11
Implementation of community-based interventions alone is unlikely to be effective for reducing most alcohol-related harms and risky alcohol consumption, according to a study by Australian researchers published in this week's PLOS Medicine. Anthony Shakeshaft and colleagues from the National Drug and Alcohol Research Centre at UNSW (University of New South Wales), report that alcohol-related crime, road-traffic crashes, and hospital inpatient admissions did not differ between communities that did and did not implement community-based interventions.
The researchers reached ...
Crowdsourced rain samples map Hurricane Sandy's evolution
2014-03-11
A unique method to collect rain water samples during Hurricane Sandy has revealed the storm's chemical "signature" with a new level of detail. The technique may also lead to weather model advances that will ultimately improve storm prediction, say researchers at the University of Utah whose study was published online today in PLOS ONE.
Hurricane Sandy, also known as Superstorm Sandy, was the deadliest and most destructive hurricane of the 2012 Atlantic hurricane season, according to government sources. Damage estimates exceed $65 billion and nearly 300 people perished ...
Lignin breakthroughs serve as GPS for plant research
2014-03-11
Researchers at North Carolina State University have developed the equivalent of GPS directions for future plant scientists to understand how plants adapt to the environment and to improve plants' productivity and biofuel potential.
Two articles published March 11 in The Plant Cell offer a step-by-step approach for studying plant traits, drawing on comprehensive, quantitative research on lignin formation in black cottonwood. Lignin, an important and complex polymer responsible for plant growth and development, provides mechanical strength and water transport that enables ...
LAST 30 PRESS RELEASES:
New strategies to enhance chiral optical signals unveiled
Cambridge research uncovers powerful virtual reality treatment for speech anxiety
2025 Gut Microbiota for Health World Summit to spotlight groundbreaking research
International survey finds that support for climate interventions is tied to being hopeful and worried about climate change
Cambridge scientist launches free VR platform that eliminates the fear of public speaking
Open-Source AI matches top proprietary model in solving tough medical cases
Good fences make good neighbors (with carnivores)
NRG Oncology trial supports radiotherapy alone following radical hysterectomy should remain the standard of care for early-stage, intermediate-risk cervical cancer
Introducing our new cohort of AGA Future Leaders
Sharks are dying at alarming rates, mostly due to fishing. Retention bans may help
Engineering excellence: Engineers with ONR ties elected to renowned scientific academy
New CRISPR-based diagnostic test detects pathogens in blood without amplification
Immunotherapy may boost KRAS-targeted therapy in pancreatic cancer
Growing solar: Optimizing agrivoltaic systems for crops and clean energy
Scientists discover how to reactivate cancer’s molecular “kill switch”
YouTube influencers: gaming’s best friend or worst enemy?
uOttawa scientists use light to unlock secret of atoms
NJIT mathematician to help map Earth's last frontier with Navy grant
NASA atmospheric wave-studying mission releases data from first 3,000 orbits
‘Microlightning’ in water droplets may have sparked life on Earth
Smoke from wildland-urban interface fires more deadly than remote wildfires
What’s your body really worth? New AI model reveals your true biological age from 5 drops of blood
Protein accidentally lassos itself, helping explain unusual refolding behavior
With bird flu in raw milk, many in U.S. still do not know risks of consuming it
University of Minnesota research team awarded $3.8 million grant to develop cell therapy to combat Alzheimer’s disease
UConn uncovers new clue on what is leading to neurodegenerative diseases like Alzheimer’s and ALS
Resuscitation in out-of-hospital cardiac arrest – it’s how quickly it is done, rather than who does it
A closer look at biomolecular ‘silly putty’
Oxytocin system of breastfeeding affected in mothers with postnatal depression
Liquid metal-enabled synergetic cooling and charging: a leap forward for electric vehicles
[Press-News.org] Infection is the leading cause of failed prosthetic knee jointsOptimizing patient health before surgery may reduce need for revisions