(Press-News.org) Phoenix — Guinea pigs and mice can be replaced with a non-animal skin sensitization method that uses a human-derived skin model, according to a study presented today by the PETA International Science Consortium, Ltd., at the Society of Toxicology's annual meeting.
Recent results show that Cyprotex's in vitro skin sensitization assay SenCeeTox® can correctly identify chemicals that cause an allergic response in humans and, unlike many other methods, can predict the potency of the response. This non-animal method uses a three-dimensional, human-derived skin model that accurately replicates many of the key traits of normal human skin, allowing it to be used to test finished products such as gels and creams.
Dr. Amy Clippinger of the PETA International Science Consortium, Ltd., presented a poster on the results of an inter-laboratory validation of the non-animal test at the Society of Toxicology's annual meeting. She explained that the test replaces guinea pigs and mice that would otherwise have chemical substances injected into their bodies or applied to their shaved skin.
PETA U.K. funded the initial validation studies. Further validation studies will be conducted, and the results will be submitted to the European Union Reference Laboratory for Alternatives to Animal Testing.
"These results show that there is no scientific need to subject tens of thousands of mice and guinea pigs to painful tests," says Jessica Sandler, director of the PETA International Science Consortium, Ltd. "We look forward to the day when old habits and archaic methods give way to good science."
INFORMATION:
With an eye toward championing the best non-animal methods and reducing duplicative testing, the PETA International Science Consortium, Ltd., brings scientific and technical expertise and extensive knowledge of the international regulatory environment to the development of regulated testing protocols.
For more information, please visit PISCLTD.org.uk and Cyprotex.com.
Contact:
Tasgola Bruner
404-907-4172
TasgolaB@peta.org
Amy Clippinger
610-701-8605
AmyJC@piscltd.org.uk
Validation study results show method can replace live animals in skin allergy tests
PETA International Science Consortium, Ltd., presents findings at Society of Toxicology meeting
2014-03-25
ELSE PRESS RELEASES FROM THIS DATE:
Don't forget F-type stars in search for life, UT Arlington researchers say
2014-03-25
Scientists searching for habitable planets beyond Earth shouldn't overlook F-type stars in favor of their more abundant, smaller and cooler cousins, according to new research from University of Texas at Arlington physicists.
Stars fall into seven lettered categories according to their surface temperature, but they also differ in other factors such as mass, luminosity and abundance in the universe. Scientists looking for habitable planets typically have focused on the less massive end of the spectrum, where our own G-type sun as well as the even less massive K and M-type ...
Model now capable of street-level storm-tide predictions
2014-03-25
The water that surged into the intersection of New York City's Canal and Hudson streets during Hurricane Sandy—to choose just one flood-ravaged locale—was ultimately driven ashore by forces swirling hundreds of miles out in the Atlantic.
That simple fact shows not only the scale and power of a tropical cyclone, but the difficulty of modeling and forecasting its potential for coastal flooding on the fine scale needed to most effectively prepare a response.
Now, a study led by Professor Harry Wang of William & Mary's Virginia Institute of Marine Science demonstrates the ...
Indian women with more resources than their husbands face heightened risk of violence
2014-03-25
NEW YORK (25 March 2014) — A new study has found that women in India who have more education than their husbands, who earn more, or who are the sole earners in their families have a higher likelihood of experiencing frequent and severe intimate partner violence (IPV) than women who are not employed or who are less educated than their spouse.
There are two existing theories that aim to predict what happens when a woman has status and resources that are equal to or greater than her husband's. One theory, called bargaining theory, posits that a woman who has more relative ...
How to look into the Solar interior
2014-03-25
An international group including one professor from the Moscow State University proposed the first ever quantitative description of the mechanism responsible for sunspot formation and underlying the Solar activity cycle.
Magnetic field helicity is one of the so-called motion invariants in magneto-hydrodynamics. It is a conserved quantity, like energy, describing the degree to which the field lines are "wrapped around themselves". During the last 20 years, scientists realized that conservation of this quantity is even more influential upon magnetic field evolution than ...
Micro systems with big commercial potential featured in SPIE journal
2014-03-25
BELLINGHAM, Washington, USA — Commercial demand is driving high-tech research and development in micro-opto-electro-mechanical systems (MOEMS) for diverse applications such as space exploration, wireless systems, and healthcare. A new special section on Emerging MOEMS Technology and Applications in the current issue of the Journal of Micro/Nanolithography, MEMS, and MOEMS (JM3) gathers recent breakthrough achievements and explains how such innovations in the photonics field are poised to emerge in the marketplace. The journal is published by SPIE, the international society ...
Mars-mimicking chamber explores habitability of other planets
2014-03-25
WASHINGTON D.C., March 25, 2014 -- A research team in Spain has the enviable job of testing out new electromechanical gear for potential use in future missions to the "Red Planet." They do it within their Mars environmental simulation chamber, which is specially designed to mimic conditions on the fourth planet from the sun -- right down to its infamous Martian dust.
Mars is a key target for future space exploration, thanks to indications that the planet may have either been capable of supporting life in the past or is possibly even supporting it right now within its ...
Malaysian microjewels going extinct as they are discovered
2014-03-25
A Malaysian-Dutch team of biologists have catalogued all 31 species of the tiny, but oh so pretty snail genus Plectostoma from West-Malaysia, Sumatra, and Thailand. Ten species are new to science, but some of those are going extinct as they are being discovered.
The study was carried out by PhD student Thor-Seng Liew of Naturalis Biodiversity Center in Leiden, The Netherlands, and three colleagues. Liew, who is on study leave from Universiti Malaysia Sabah, spent four years studying the distribution, shell shape, and genetics of these minuscule snails. He is still working ...
First stem cell study of bipolar disorder yields promising results
2014-03-25
ANN ARBOR, Mich. — What makes a person bipolar, prone to manic highs and deep, depressed lows? Why does bipolar disorder run so strongly in families, even though no single gene is to blame? And why is it so hard to find new treatments for a condition that affects 200 million people worldwide?
New stem cell research published by scientists from the University of Michigan Medical School, and fueled by the Heinz C. Prechter Bipolar Research Fund, may help scientists find answers to these questions.
The team used skin from people with bipolar disorder to derive the first-ever ...
Fewer children at risk for deficient vitamin D
2014-03-25
MAYWOOD, Il. – Under new guidelines from the Institute of Medicine, the estimated number of children who are at risk for having insufficient or deficient levels of vitamin D is drastically reduced from previous estimates, according to a Loyola University Chicago Stritch School of Medicine study.
The study, led by Holly Kramer, MD, MPH and Ramon Durazo-Arvizu, PhD, is published online ahead of print in the Journal of Pediatric Endocrinology and Metabolism.
New Institute of Medicine guidelines say most people get sufficient vitamin D when their blood levels are at or ...
Black markets for hackers are increasingly sophisticated, specialized and maturing
2014-03-25
Black and gray markets for computer hacking tools, services and byproducts such as stolen credit card numbers continue to expand, creating an increasing threat to businesses, governments and individuals, according to a new RAND Corporation study.
One dramatic example is the December 2013 breach of retail giant Target, in which data from approximately 40 million credit cards and 70 million user accounts was hijacked. Within days, that data appeared -- available for purchase -- on black market websites.
"Hacking used to be an activity that was mainly carried out by individuals ...
LAST 30 PRESS RELEASES:
Medicaid expansion linked to improved long-term survival in cancer patients
Women with surgical menopause may exit workforce earlier, but hormone therapy could help
Trailblazing Young Scientists honored with $250,000 prizes at Blavatnik National Awards Gala
Revolutionary blood test for ME / Chronic Fatigue unveiled
Calorie labelling linked to 2% average reduction in energy content of menu items
Widely prescribed opioid painkiller tramadol not that effective for easing chronic pain
Exercise snacks may boost cardiorespiratory fitness of physically inactive adults
15,000 women a year with breast cancer could benefit from whole genome sequencing, say researchers
Study highlights risks of Caesarean births to future pregnancies
GLP-1 agonists pose emerging challenge for PET-CT imaging, study finds
Scripps Research scientists unlock new patterns of protein behavior in cell membranes
Panama Canal may face frequent extreme water lows in coming decades
Flash Joule heating lights up lithium extraction from ores
COMBINEDBrain and MUSC announce partnership to establish biorepository for pediatric cerebrospinal fluid and CNS tissue bank
Questionable lead reporting for drinking water virtually vanished after Flint water crisis, study reveals
Assessing overconfidence among national security officials
Bridging two frontiers: Mitochondria & microbiota, Targeting Extracellular Vesicles 2025 to explore game-changing pathways in medicine
New imaging tech promises to help doctors better diagnose and treat skin cancers
Once dominant, US agricultural exports falter amid trade disputes and rising competition
Biochar from invasive weed shields rice from toxic nanoplastics and heavy metals
Rice University announces second cohort of Chevron Energy Graduate Fellows
Soil bacteria and minerals form a natural “battery” that breaks down antibiotics in the dark
Jamestown colonists brought donkeys, not just horses, to North America, old bones reveal
FIU cybersecurity researchers develop midflight defense against drone hijacking
Kennesaw State researcher aims to discover how ideas spread in the digital age
Next-generation perovskite solar cells are closer to commercial use
Sleep patterns linked to variation in health, cognition, lifestyle, and brain organization
University of Oklahoma researcher awarded funding to bridge gap between molecular data and tissue architecture
Nationally-recognized pathologist Paul N. Staats, MD, named Chair of Pathology at University of Maryland School of Medicine
The world’s snow leopards are very similar genetically. That doesn’t bode well for their future
[Press-News.org] Validation study results show method can replace live animals in skin allergy testsPETA International Science Consortium, Ltd., presents findings at Society of Toxicology meeting