PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Natural plant compounds may assist chemotherapy

2014-03-27
(Press-News.org) Auckland, New Zealand. 27 March 2014...Researchers at Plant & Food Research have identified plant compounds present in carrots and parsley that may one day support more effective delivery of chemotherapy treatments.

Scientists at Plant & Food Research, working together with researchers at The University of Auckland and the National Cancer Institute of The Netherlands, have discovered specific plant compounds able to inhibit transport mechanisms in the body that select what compounds are absorbed into the body,and eventually into cells. These same transport mechanisms are known to interfere with cancer chemotherapy treatment.

The teams' research, recently published in the European Journal of Pharmacology, showed that falcarinol type compounds such as those found in carrots and parsley may support the delivery of drug compounds which fight breast cancer by addressing the over-expression of Breast Cancer Resistance Protein (BCRP/ABCG2), a protein that leads to some malignant tissues ability to become resistant to chemotherapy.

"It's very exciting work," says Plant & Food Research Senior Scientist, Dr Arjan Scheepens. "Our work is uncovering new means to alter how the body absorbs specific chemical and natural compounds. Ultimately we are interested in how food could be used to complement conventional treatments to potentially deliver better results for patients."

INFORMATION: END


ELSE PRESS RELEASES FROM THIS DATE:

Smoke-free air policies seem to protect the heart

2014-03-27
WASHINGTON (March 27, 2014) — A new study on the impact of Michigan's statewide smoking ban adds to mounting evidence that policies prohibiting tobacco smoking in workplaces and other public spaces may substantially improve public health by reducing heart disease and death, according to research to be presented at the American College of Cardiology's 63rd Annual Scientific Session. Studies on previous indoor smoking bans have consistently shown a major decrease in hospital admissions for heart attacks after smoke-free laws went into effect. Secondhand smoke exposure is ...

The heart responds differently to exercise in men vs. women

2014-03-27
WASHINGTON (March 27, 2014) — The formula for peak exercise heart rate that doctors have used for decades in tests to diagnose heart conditions may be flawed because it does not account for differences between men and women, according to research to be presented at the American College of Cardiology's 63rd Annual Scientific Session. The simple formula of "220 minus age" has been widely used to calculate the maximum number of heart beats per minute a person can achieve. Many people use it to derive their target heart rate during a workout. Doctors use it to determine how ...

Cholesterol levels vary by season, get worse in colder months

2014-03-27
WASHINGTON (March 27, 2014) — Cholesterol levels fluctuate based on the time of year with more unfavorable lipid profiles seen in the colder months, a trend that may be driven by related behavior changes, according to research to be presented at the American College of Cardiology's 63rd Annual Scientific Session. While previous studies have shown that heart attacks and heart-related deaths increase during the winter months, researchers at Johns Hopkins Ciccarone Center for the Prevention of Heart Disease were interested in finding out whether cholesterol parameters might ...

Mediterranean diet may lower risk of diabetes

2014-03-27
WASHINGTON (March 27, 2014) — Adoption of a Mediterranean diet is linked to a lower risk of diabetes, especially among people at high risk for cardiovascular disease, according to research to be presented at the American College of Cardiology's 63rd Annual Scientific Session. Data from the first pooled analysis of studies evaluating the possible role of the Mediterranean diet on diabetes development show that adherence to this diet was associated with a 21 percent reduced risk of diabetes as compared to the control dietary groups. This reduced risk was even more pronounced ...

Marathon training could help the heart

2014-03-27
WASHINGTON (March 27, 2014) — Marathon training is associated with improved risk factors related to cardiovascular disease among middle-aged recreational male runners, suggesting that race preparation may be an effective strategy for reducing heart disease risk, according to research to be presented at the American College of Cardiology's 63rd Annual Scientific Session. Over the last decade, marathon participation has risen steadily among middle-aged people seeking the reported health benefits of regular physical exercise. Some studies have shown that older men are significantly ...

More severe heart disease found in patients with vitamin D deficiency

2014-03-27
WASHINGTON (March 27, 2014) — Vitamin D deficiency is an independent risk factor for heart disease with lower levels of vitamin D being associated with a higher presence and severity of coronary artery disease, according to research to be presented at the American College of Cardiology's 63rd Annual Scientific Session. A growing body of research shows that vitamin D may be beneficial in preventing heart disease. Several recent studies also support the idea that low levels of vitamin D are linked to an increased risk of heart disease; however, it is still not clear whether ...

Clusters of 'broken hearts' may be linked to massive natural disasters

2014-03-27
WASHINGTON (March 27, 2014) — Dramatic spikes in cases of Takotsubo cardiomyopathy, also called broken heart syndrome, were found in two states after major natural disasters, suggesting the stress of disasters as a likely trigger, according to research to be presented at the American College of Cardiology's 63rd Annual Scientific Session. Authors call for greater awareness among emergency department physicians and other first responders. Takotsubo cardiomyopathy, or broken heart syndrome, is a disorder characterized by a temporary enlargement and weakening of the heart ...

Artificial hearts may help patients survive until transplant

2014-03-27
WASHINGTON (March 27, 2014) — The largest single-center study of patients implanted with a total artificial heart finds the device may help patients in severe heart failure survive until they can receive a heart transplant, according to research to be presented at the American College of Cardiology's 63rd Annual Scientific Session. Researchers studied 22 patients implanted with total artificial hearts at Cedars-Sinai Heart Institute in 2012 and 2013 to look at the primary endpoints of death and incidence of stroke at 60 days. They found that five patients had died, four ...

Sleep may stop chronic pain sufferers from becoming zombies

Sleep may stop chronic pain sufferers from becoming zombies
2014-03-27
Chronic pain sufferers could be kept physically active by improving the quality of their sleep, new research suggests. The study by the University of Warwick's Department of Psychology, published in PLoS One, found that sleep was a worthy target for treating chronic pain and not only as an answer to pain-related insomnia. "Engaging in physical activity is a key treatment process in pain management. Very often, clinicians would prescribe exercise classes, physiotherapy, walking and cycling programmes as part of the treatment, but who would like to engage in these activities ...

Southerners more likely to die from heart attack

2014-03-27
WASHINGTON (March 27, 2014) — Although heart attack death has declined across all regions of the United States, it is proportionately higher in the South, possibly related to the uneven distribution of socioeconomic and traditional cardiovascular risk factors, according to research to be presented at the American College of Cardiology's 63rd Annual Scientific Session. While rates of cardiovascular disease vary by state and region of the country, little is known about geographic variation in associated death rates. In the first retrospective study to examine heart attack ...

LAST 30 PRESS RELEASES:

New perspective highlights urgent need for US physician strike regulations

An eye-opening year of extreme weather and climate

Scientists engineer substrates hostile to bacteria but friendly to cells

New tablet shows promise for the control and elimination of intestinal worms

Project to redesign clinical trials for neurologic conditions for underserved populations funded with $2.9M grant to UTHealth Houston

Depression – discovering faster which treatment will work best for which individual

Breakthrough study reveals unexpected cause of winter ozone pollution

nTIDE January 2025 Jobs Report: Encouraging signs in disability employment: A slow but positive trajectory

Generative AI: Uncovering its environmental and social costs

Lower access to air conditioning may increase need for emergency care for wildfire smoke exposure

Dangerous bacterial biofilms have a natural enemy

Food study launched examining bone health of women 60 years and older

CDC awards $1.25M to engineers retooling mine production and safety

Using AI to uncover hospital patients’ long COVID care needs

$1.9M NIH grant will allow researchers to explore how copper kills bacteria

New fossil discovery sheds light on the early evolution of animal nervous systems

A battle of rafts: How molecular dynamics in CAR T cells explain their cancer-killing behavior

Study shows how plant roots access deeper soils in search of water

Study reveals cost differences between Medicare Advantage and traditional Medicare patients in cancer drugs

‘What is that?’ UCalgary scientists explain white patch that appears near northern lights

How many children use Tik Tok against the rules? Most, study finds

Scientists find out why aphasia patients lose the ability to talk about the past and future

Tickling the nerves: Why crime content is popular

Intelligent fight: AI enhances cervical cancer detection

Breakthrough study reveals the secrets behind cordierite’s anomalous thermal expansion

Patient-reported influence of sociopolitical issues on post-Dobbs vasectomy decisions

Radon exposure and gestational diabetes

EMBARGOED UNTIL 1600 GMT, FRIDAY 10 JANUARY 2025: Northumbria space physicist honoured by Royal Astronomical Society

Medicare rules may reduce prescription steering

Red light linked to lowered risk of blood clots

[Press-News.org] Natural plant compounds may assist chemotherapy