Anti-clotting agent helps reduce the incidence and impact of stent thrombosis during PCI

Results from an angiographic analysis of the CHAMPION PHOENIX trial to be presented at ACC 14

2014-03-27

(Press-News.org) WASHINGTON, DC – March 27, 2014 –A new angiographic analysis of the CHAMPION PHOENIX trial examined the incidence and impact of stent thrombosis (ST) in patients undergoing percutaneous coronary intervention (PCI). Results of the study were released today and will be presented March 30 at the American College of Cardiology 63rd Annual Scientific Session.

CHAMPION PHOENIX was a prospective, double-blind, active-controlled trial which randomized 11,145 patients to receive intravenous cangrelor or oral clopidogrel administered at the time of PCI. In a previous analysis presented at TCT 2013 and published in the Journal of the American College of Cardiology, cangrelor significantly reduced periprocedural and 30-day ischemic events in patients undergoing PCI.

In this new analysis, an independent core laboratory (CRF) blinded to the treatment performed the angiographic analysis of 10,939 of the randomized patients. Stent thrombosis was defined as the occurrence of either intraprocedural ST (IPST) or ARC defined ST (definite or probable). Adverse events were adjudicated by an independent clinical events committee.

ST occurred in 120 patients (1.1 percent) at 48 hours and in 175 patients (1.6 percent) at 30 days. The occurrence of ST at 48 hours and 30 days was associated with a marked increase in 30-day mortality (OR [95%CI] = 15.3 [8.6, 27.2], p END

ELSE PRESS RELEASES FROM THIS DATE:

A tale of 2 species

2014-03-27

A pair of new studies from the Wildlife Conservation Society, Idaho State University, and the University of Nevada Reno look at the surprising variety of factors that prevent two closely related species of woodrats from becoming a single hybrid species despite the existence of hybrid individuals where the two species come into contact. After finding that two closely related species, the desert and Bryant's woodrats, could interbreed and produce hybrid offspring, scientists set out to determine why only 14 percent of the population in a "contact zone" had genetic signatures ...

Satellite time-lapse movie shows US East Coast snowy winter

2014-03-27

VIDEO: This new animation of NOAA's GOES-East satellite imagery shows the movement of winter storms from Jan. 1 to Mar. 24 making for a snowier-than-normal winter along the US East Coast... Click here for more information. A new time-lapse animation of data from NOAA's GOES-East satellite provides a good picture of why the U.S. East Coast experienced a snowier than normal winter. The new animation shows the movement of storms from January 1 to March 24. NOAA's Geostationary ...

Food insecurity a growing challenge in Canada's northern and remote Aboriginal communities

2014-03-27

Ottawa (March 27, 2014) – A new expert panel report on food security in Northern Canada, has found that food insecurity among northern Aboriginal peoples requires urgent attention in order to mitigate impacts on health and well-being. Aboriginal Food Security in Northern Canada: An Assessment of the State of Knowledge, released today by the Council of Canadian Academies, addresses the diversity of experience that northern First Nations, Inuit, and Métis households and communities have with food insecurity. Aboriginal households across Canada experience food insecurity ...

Computing with slime

2014-03-27

Oxford, March 27, 2014 - A future computer might be a lot slimier than the solid silicon devices we have today. In a study published in the journal Materials Today, European researchers reveal details of logic units built using living slime molds, which might act as the building blocks for computing devices and sensors. Andrew Adamatzky (University of the West of England, Bristol, UK) and Theresa Schubert (Bauhaus-University Weimar, Germany) have constructed logical circuits that exploit networks of interconnected slime mold tubes to process information. One is more ...

Study finds gaming augments players' social lives

2014-03-27

New research finds that online social behavior isn't replacing offline social behavior in the gaming community. Instead, online gaming is expanding players' social lives. The study was done by researchers at North Carolina State University, York University and the University of Ontario Institute of Technology. "Gamers aren't the antisocial basement-dwellers we see in pop culture stereotypes, they're highly social people," says Dr. Nick Taylor, an assistant professor of communication at NC State and lead author of a paper on the study. "This won't be a surprise to the ...

People unwilling to swallow soda tax, size restrictions

2014-03-27

ITHACA, N.Y. – Those hoping to dilute Americans' taste for soda, energy drinks, sweetened tea, and other sugary beverages should take their quest to school lunchrooms rather than legislative chambers, according to a recent study by media and health policy experts. Soda taxes and beverage portion size restrictions were unpalatable to the 1,319 U.S. adults questioned in a fall 2012 survey as part of a study reported online this month in the journal Preventive Medicine. Adding front-of-package nutrition labels and removing sugary beverages from school environments garnered ...

Agroforestry systems can repair degraded watersheds

2014-03-27

NAIROBI, Kenya. (27 March 2014) ----Agroforestry, combined with land and water management practices that increase agricultural productivity, can save watersheds from degradation. A study conducted by the World Agroforestry Centre (ICRAF) in the Gabayan watershed in eastern Bohol, Philippines, has shown that agroforestry systems create a more sustainably managed watershed that allows people living there to benefit from the ecosystem. The benefits include higher crop yields, increased income and resilience to climate change. Agroforestry is an integrated land-use management ...

Scientists watch nanoparticles grow

2014-03-27

This news release is available in German. With DESY's X-ray light source PETRA III, Danish scientists observed the growth of nanoparticles live. The study shows how tungsten oxide nanoparticles are forming from solution. These particles are used for example for smart windows, which become opaque at the flick of a switch, and they are also used in particular solar cells. The team around lead author Dr. Dipankar Saha from Århus University present their observations in the scientific journal Angewandte Chemie – International Edition. For their investigation, the scientists ...

Record quantum entanglement of multiple dimensions

2014-03-27

The states in which elementary particles, such as photons, can be found have properties which are beyond common sense. Superpositions are produced, such as the possibility of being in two places at once, which defies intuition. In addition, when two particles are entangled a connection is generated: measuring the state of one (whether they are in one place or another, or spinning one way or another, for example) affects the state of the other particle instantly, no matter how far away from each other they are. Scientists have spent years combining both properties to construct ...

A more potent greenhouse gas than CO2, methane emissions will leap as Earth warms

2014-03-27

While carbon dioxide is typically painted as the bad boy of greenhouse gases, methane is roughly 30 times more potent as a heat-trapping gas. New research in the journal Nature indicates that for each degree that the Earth's temperature rises, the amount of methane entering the atmosphere from microorganisms dwelling in lake sediment and freshwater wetlands — the primary sources of the gas — will increase several times. As temperatures rise, the relative increase of methane emissions will outpace that of carbon dioxide from these sources, the researchers report. The findings ...

LAST 30 PRESS RELEASES:

Small but mighty: A biomimetic idea takes flight

New hydrogel-based treatment accelerates infected wound healing and balances skin microbiota

New bioactive dressing promises faster diabetic wound healing

Japan launches fully domestically produced quantum computer

Home is where the airfields are: What happens when hawks are moved from Los Angeles airports

Study: Sylvester researchers uncover molecular drivers of cellular differentiation

Withdrawal of kidney treatment significantly benefits patients and NHS

Illinois Tech hosts EV Readiness Community Awards, showcasing nation-leading energy innovation

Rice bioscientist wins NSF CAREER Award to investigate bacterial toxins, expand inclusion in STEM

Study links exercise with decreased mortality and cardiovascular events in people recently diagnosed with type 2 diabetes but no previous cardiovascular disease