(Press-News.org) New Rochelle, NY, April 1, 2014 -- Rare, very small embryonic-like stem cells (VSELs) isolated from human adult tissues could provide a new source for developing regenerative therapies to repair complex tissues damaged by disease or trauma. The ability of these most-primitive, multipotent stem cells to differentiate into bone, neurons, connective tissue, and other cell types, and the proper criteria for identifying and isolating VSELs, are described in two articles in Stem Cells and Development, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The articles are available on the Stem Cells and Development website.
Russ Taichman and coauthors, University of Michigan (Ann Arbor) and NeoStem (New York, NY), implanted human VSELs into the cavity created by a cranial wound and provided the first demonstration that they could generate tissue structures containing multiple cell types. Their work is presented in "Human and Murine Very Small Embryonic-Like (VSEL) Cells Represent Multipotent Tissue Progenitors, In Vitro and In Vivo."
Malwina Suszynska et al., University of Louisville, KY, and Pomeranian Medical University (Szczecin) and Jagiellonian University (Krakow), Poland, explore the challenges in isolating these rare stem cells and the importance of not confusing VSELs with other types of embryonic or reprogrammed adult pluripotent stem cells, or with monopotent adult stem cells. In the Issues in Development article "The Proper Criteria for Identification and Sorting of Very Small Embryonic-Like Stem Cells (VSELs), and Some Nomenclature Issues," the authors present the most current descriptions and terminology for characterizing VSELs.
"I find the data presented by the Taichman group to be compelling and challenging. However, the current debate as to the significance of the body of publications concerning VSELs can only be resolved by a cooperative investigation across laboratories using identical methodologies and source materials," says Editor-in-Chief Graham C. Parker, PhD, The Carman and Ann Adams Department of Pediatrics, Wayne State University School of Medicine, Detroit, MI.
INFORMATION:
About the Journal
Stem Cells and Development is an authoritative peer-reviewed journal published 24 times per year in print and online. The Journal is dedicated to communication and objective analysis of developments in the biology, characteristics, and therapeutic utility of stem cells, especially those of the hematopoietic system. Complete tables of content and a free sample issue may be viewed on the Stem Cells and Development website.
About the Publisher
Mary Ann Liebert, Inc., publishers is a privately held, fully integrated media company known for establishing authoritative peer-reviewed journals in promising areas of science and biomedical research, including Cellular Reprogramming, Tissue Engineering, and Human Gene Therapy. Its biotechnology trade magazine, Genetic Engineering & Biotechnology News (GEN), was the first in its field and is today the industry's most widely read publication worldwide. A complete list of the firm's 80 journals, books, and newsmagazines is available on the Mary Ann Liebert, Inc., publishers website.
Mary Ann Liebert, Inc. 140 Huguenot St., New Rochelle, NY 10801-5215
Phone: (914) 740-2100 (800) M-LIEBERT Fax: (914) 740-2101
http://www.liebertpub.com
First evidence that very small embryonic-like stem cells
From human adult tissues are multipotent
2014-04-01
ELSE PRESS RELEASES FROM THIS DATE:
Survey shows spine surgeons need to screen more patients for anxiety and depression
2014-04-01
In a report published in the April edition of the Journal of Spinal Disorders and Techniques, a Johns Hopkins team says that only 10 percent of orthopaedic surgeons and neurosurgeons follow professional guidelines recommending routine psychological screenings of patients prior to major surgery for severe back and leg pain.
The oversight, researchers say, may pose a serious risk to patients' surgical recovery. Previous reports have tied bouts of depression to longer recuperations, delayed returns to work, more postsurgical complications and failures to comply with medication ...
Overcoming structural uncertainty in computer models
2014-04-01
Philadelphia, PA--A computer model is a representation of the functional relationship between one set of parameters, which forms the model input, and a corresponding set of target parameters, which forms the model output. A true model for a particular problem can rarely be defined with certainty. The most we can do to mitigate error is to quantify the uncertainty in the model.
In a recent paper published in the SIAM/ASA Journal on Uncertainty Quantification, authors Mark Strong and Jeremy Oakley offer a method to incorporate judgments into a model about structural uncertainty ...
Want spring allergy relief? Avoid stress
2014-04-01
ARLINGTON HEIGHTS, Ill. (April 1, 2014) – Stress doesn't cause allergies, but easing your mind might mean less allergy flare-ups this spring. According to a study published in the April issue of Annals of Allergy, Asthma & Immunology, the scientific journal of the American College of Allergy, Asthma and Immunology, allergy sufferers with persistent stress experience more allergy flares.
"Stress can cause several negative effects on the body, including causing more symptoms for allergy sufferers," said allergist Amber Patterson, MD, lead study author and ACAAI member. ...
Scientists ID genes that could lead to tough, disease-resistant varieties of rice
2014-04-01
As the Earth's human population marches toward 9 billion, the need for hardy new varieties of grain crops has never been greater.
It won't be enough to yield record harvests under perfect conditions. In an era of climate change, pollution and the global spread of pathogens, these new grains must also be able to handle stress. Now, researchers at Michigan Technological University have identified a set of genes that could be key to the development of the next generation of super rice.
A meta-data analysis by biologist Ramakrishna Wusirika and PhD student Rafi Shaik has ...
Pause the paunch and halt the hair loss
2014-04-01
In particular, the protein that activated hair follicle growth was shown to also inhibit fat production.
The world first research confirmed that changes in the hair growth cycle led to fluctuations in the thickness of the underlying fat layer of the skin – essentially meaning that the skin can regulate fat production.
The research was led by Professor Fiona Watt at King's College London in collaboration with Professor of Dermatology Rodney Sinclair from the University of Melbourne and Epworth Hospital.
Professor Sinclair said these findings could potentially be ...
Higher risk of death from skin cancer among men living alone
2014-04-01
There are differences in prognosis in cutaneous malignant melanoma depending on cohabitation status and gender, according to a new study published in the scientific periodical Journal of Clinical Oncology. Single men of all ages are more likely to die of their disease.
Cutaneous malignant melanoma is the most aggressive form of skin cancer. The disease is one of the fastest growing cancers among Caucasian (white) populations and is an escalating health problem even among young individuals. Swedish researchers from Karolinska Institutet and Linköping University have now, ...
Universal syllables
2014-04-01
Take the sound "bl": how many words starting with that sound can you think of? Blouse, blue, bland... Now try with "lb": how many can you find? None in English and Italian, and even in other languages such words either don't exist or are extremely rare. Human languages offer several examples of this kind, and this indicates that in forming words we tend to prefer certain sound combinations to others, irrespective of which language we speak. The fact that this occurs across languages has prompted linguists to hypothesize the existence of biological bases of language (inborn ...
1.1 million Americans caring for recently wounded veterans, study finds
2014-04-01
More than 1.1 million spouses, parents and friends are caring for the injured and disabled who have served in the U.S. military since Sept. 11, 2001, often doing so without a formal support network and putting their own well-being at risk, according to a new RAND Corporation study.
The largest-ever study of military caregivers -- commissioned by the Elizabeth Dole Foundation -- finds that Americans who are taking care of veterans who served after 9/11 are younger than other caregivers, are usually employed outside the home and are more likely to care for someone who has ...
Customers prefer restaurants that offer nutrition facts and healthful foods
2014-04-01
Customers are more likely to frequent restaurants that provide both healthful foods and nutrition information, according to researchers at Penn State and the University of Tennessee.
"The Affordable Care Act has mandated that chain restaurants -- those with more than 20 restaurants -- provide nutrition information to customers," said David Cranage, associate professor of hospitality management. "Many restaurants had been fighting this legislation because they thought they would lose customers if the customers knew how unhealthy their food was. In this study, we found ...
New yeast species travelled the globe with a little help from the beetles
2014-04-01
Researchers from the National Collection of Yeast Cultures (NCYC) at the Institute of Food Research (IFR) have identified a new globe-trotting yeast species that lives on tree-associated beetles. This new species demonstrates the importance of preserving biodiversity, as yeasts like this may help efforts to develop renewable fuel sources in the future.
Preserving biodiversity must go beyond plants and animals and also preserve the microbial life. Threats to habitats, for example through oil exploration, could destroy forever potential solutions to global challenges locked ...
LAST 30 PRESS RELEASES:
Washington coast avian flu outbreak devastated Caspian terns, jumped to seals
Mice tails whip up new insights into balance and neurodegenerative disease research
New study: Earthquake prediction techniques lend quick insight into strength, reliability of materials
Vitamin D during pregnancy boosts children’s bone health even at age seven
Use of “genetic scissors” carries risks
Does work-related stress compromise cardiovascular health?
New research may lead to potatoes that are less reliant on nitrogen fertilizers
Do commercial ties influence ESG ratings?
Study assesses "gendered space" in financial institutions in Pakistan
Chinese herbal medicine’s potential in preventing dementia
Firms that read more perform better
Tightly tied waist cord of saree underskirt may pose cancer risk, warn doctors
10% of children in high-burden tuberculosis settings may develop the disease by age 10
Health experts push for the elimination of a ‘remarkably harmful toxin’
University of Tennessee, Lockheed Martin expand Master Research Agreement
Testing thousands of RNA enzymes helps find first ‘twister ribozyme’ in mammals
Groundbreaking study provides new evidence of when Earth was slushy
International survey of more than 1600 biomedical researchers on the perceived causes of irreproducibility of research results
Integrating data from different experimental approaches into one model is challenging – this study presents a community-based, full-scale in silico model of the rat hippocampal CA1 region that integra
SwRI awarded grant to characterize Las Moras Springs watershed
Water overuse in MATOPIBA could mean failure to meet up to 40% of local demand for crop irrigation
An extra year of education does not protect against brain aging
Researchers from Uppsala and Magdeburg obtain an ERC Synergy Grant to advance cancer immunotherapy
Deaf male mosquitoes don’t mate
Recognizing traumatic brain injury as a chronic condition fosters better care over the survivor’s lifetime
SwRI’s Dr. James Walker receives Distinguished Scientist Award from Hypervelocity Impact Society
A mother’s health problems pose a risk to her children
Ensuring a bright future for diamond electronics and sensors
The American Pediatric Society selects Dr. Maria Trent as the Recipient of the 2025 David G. Nichols Health Equity Award
The first 3D view of the formation and evolution of globular clusters
[Press-News.org] First evidence that very small embryonic-like stem cellsFrom human adult tissues are multipotent