World Alzheimer Report 2014 reveals persuasive evidence for dementia risk reduction

(Press-News.org) The World Alzheimer Report 2014 'Dementia and Risk Reduction: An analysis of protective and modifiable factors', released today, calls for dementia to be integrated into both global and national public health programmes alongside other major non communicable diseases (NCDs).

Alzheimer's Disease International (ADI) commissioned a team of researchers, led by Professor Martin Prince from King's College London, to produce the report. ADI is publishing this report, in conjunction with World Alzheimer's Day™ (21 September) and as a part of World Alzheimer's Month, an international campaign to raise awareness and challenge stigma.

The report reveals that control of diabetes and high blood pressure as well as measures to encourage smoking cessation and to reduce cardiovascular risk, have the potential to reduce the risk of dementia even in late-life. The report found that diabetes can increase the risk of dementia by 50%. Obesity and lack of physical activity are important risk factors for diabetes and hypertension, and should, therefore, also be targeted.

While cardiovascular health is improving in many high income countries, many low and middle income countries show a recent pattern of increasing exposure to cardiovascular risk factors, with rising rates of diabetes, heart disease and stroke.

Smoking cessation is strongly linked in the report with a reduction in dementia risk. For example, studies of dementia incidence among people aged 65 years and over show that ex-smokers have a similar risk to those who have never smoked, while those who continue to smoke are at much higher risk.

Furthermore, the study revealed that those who have had better educational opportunities have a lower risk of dementia in late-life. Evidence suggests that education has no impact on the brain changes that lead to dementia, but reduces their impact on intellectual functioning.

The evidence in the report suggest that if we enter old age with better developed, healthier brains we are likely to live longer, happier and more independent lives, with a much reduced chance of developing dementia. Brain health promotion is important across the life span, but particularly in mid-life, as changes in the brain can begin decades before symptoms appear.

The study also urges NCD programs to be more inclusive of older people, with the message that it's never too late to make a change, as the future course of the global dementia epidemic is likely to depend crucially upon the success or failure of efforts to improve global public health, across the population. Combining efforts to tackle the increasing global burden of NCDs will be strategically important, efficient and cost effective. Leading a healthier lifestyle is a positive step towards preventing a range of long-term diseases, including cancer, heart disease, stroke and diabetes.

However, survey data released by Bupa* has shown that many people are unclear about the causes and actions they can take to potentially reduce their risk of dementia. Just over a sixth (17%) of people realised that social interaction with friends and family could impact on the risk. Only a quarter (25%) identified being overweight as a possible factor, and only one in five (23%) said physical activity could affect the risk of developing dementia and losing their memories. The survey also revealed that over two thirds (68%) of people surveyed around the world are concerned about getting dementia in later life.

Professor Martin Prince, from King's College London's Institute of Psychiatry, Psychology & Neuroscience and author of the report, commented: "There is already evidence from several studies that the incidence of dementia may be falling in high income countries, linked to improvements in education and cardiovascular health. We need to do all we can to accentuate these trends. With a global cost of over US$ 600 billion, the stakes could hardly be higher."

Marc Wortmann, Executive Director, Alzheimer's Disease International said: "From a public health perspective, it is important to note that most of the risk factors for dementia overlap with those for the other major non communicable diseases (NCDs). In high income countries, there is an increased focus on healthier lifestyles, but this is not always the case with lower and middle income countries. By 2050, we estimate that 71% of people living with dementia will live in these regions, so implementing effective public health campaigns may help to reduce the global risk."

Professor Graham Stokes, Global Director of Dementia Care, Bupa, said: "While age and genetics are part of the disease's risk factors, not smoking, eating more healthily, getting some exercise, and having a good education, coupled with challenging your brain to ensure it is kept active, can all play a part in minimising your chances of developing dementia. People who already have dementia, or signs of it, can also do these things, which may help to slow the progression of the disease."

INFORMATION: The full report will be available here once the embargo lifts: http://www.alz.co.uk/worldreport2014

The full survey results will be available at http://www.bupa.com/dementia

These figures, unless otherwise stated, are from YouGov Plc. Total sample size was 8,513, from the UK (2,401), Australia (1,000), Chile (1,000), China (1,031), Poland (1,002), and Spain (1,077). Fieldwork was undertaken online, between 17󈞅 July 2014. The figures have been weighted and are representative of all adults (aged 18+) in each country. An even weighting was applied to each country to find a 'Global Average'.

Available for interview Professor Martin Prince, King's College London's Institute of Psychiatry, Psychology & Neuroscience Marc Wortmann, Executive Director, Alzheimer's Disease International Professor Graham Stokes, Director of Dementia Care, Bupa Media Contacts Anastasia Psoma
Project and Communications Coordinator
Alzheimer's Disease International
a.psoma@alz.co.uk
+44 (0) 7990 869 052 Jo Hudson
Head of Media, Bupa
joanne.hudson@bupa.com
+44 (0)20 7656 2273 Seil Collins
Press Officer
Institute of Psychiatry
Psychology & Neuroscience
King's College London
Seil.collins@kcl.ac.uk
+44 (0) 207 848 5377
+44 (0)7718 697 176

About Alzheimer's Disease International ADI is the international federation of 84 Alzheimer associations around the world, in official relations with the World Health Organization. ADI's vision is an improved quality of life for people with dementia and their families throughout the world. ADI believes that the key to winning the fight against dementia lies in a unique combination of global solutions and local knowledge. As such, it works locally, by empowering Alzheimer associations to promote and offer care and support for people with dementia and their carers, while working globally to focus attention on dementia and campaign for policy change from governments. For more information, visit http://www.alz.co.uk

About King's College London King's College London is one of the top 20 universities in the world (2013/14 QS World University Rankings) and the fourth oldest in England. It is The Sunday Times 'Best University for Graduate Employment 2012/13'. King's has nearly 26,000 students (of whom more than 10,600 are graduate students) from some 140 countries worldwide, and more than 7,000 staff. The College is in the second phase of a £1 billion redevelopment programme which is transforming its estate. King's has an outstanding reputation for providing world-class teaching and cutting-edge research. In the 2008 Research Assessment Exercise for British universities, 23 departments were ranked in the top quartile of British universities; over half of our academic staff work in departments that are in the top 10 per cent in the UK in their field and can thus be classed as world leading. The College is in the top seven UK universities for research earnings and has an overall annual income of nearly £590 million.

About Bupa Bupa's purpose is longer, healthier, happier lives. As a leading international healthcare group, we offer health insurance and medical subscription products, run care homes, retirement villages, hospitals, primary care centres and dental clinics. We also provide workplace health services, home healthcare, health assessments and long-term condition management services. We have over 22 million customers in 190 countries. With no shareholders, we invest our profits to provide more and better healthcare and fulfil our purpose. We employ more than 70,000 people, principally in the UK, Australia, Spain, Poland, New Zealand and Chile, as well as Saudi Arabia, Hong Kong, India, Thailand, and the USA. Bupa is the largest international provider of specialist dementia care, caring for more than 24,000 residents with dementia. For more information, visit http://www.bupa.com