Dangerous blood clots: A serious global problem
2014-10-10
(Press-News.org) A study on the global burden of venous thromboembolism—when a dangerous clot forms in a blood vessel—found that annual incidences range from 0.75 to 2.69 per 1,000 individuals in the population. The incidence increased to between 2 and 7 per 1,000 among those 70 years of age or more.
"Venous thromboembolism in hospitalized patients was responsible for more years lost due to ill-health than hospital-acquired pneumonia, catheter-related blood stream infections, and side effects from drugs," said Dr. Gary Raskob, co-author of the Journal of Thrombosis & Haemostasis study.
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2014-10-10
Philadelphia, PA, October 9, 2014 – Researchers at Sanford-Burnham Medical Research Institute have identified a set of RNA molecules that are detectable in tissue samples and urine of prostate cancer patients but not in normal healthy individuals. The study sets the stage for the development of more sensitive and specific noninvasive tests for prostate cancer than those currently available, which could result in fewer unnecessary prostate biopsies with less treatment-related morbidity, according to a new study in The Journal of Molecular Diagnostics.
According to ...
2014-10-10
Stanford engineers have invented a wireless pressure sensor that has already been used to measure brain pressure in lab mice with brain injuries.
The underlying technology has such broad potential that it could one day be used to create skin-like materials that can sense pressure, leading to prosthetic devices with the electronic equivalent of a sense of touch.
A nine-member research team led by Chemical Engineering Professor Zhenan Bao detailed two medical applications of this technology in Nature Communications.
In one simple demonstration they used this wireless ...
2014-10-10
Researchers from the University of Melbourne have established how two diseases that present in similar ways are in fact quite different.
Progressive Supranuclear palsy and Parkinson's Disease have overlapping symptoms but remain difficult to distinguish.
However, a first ever paper on the topic published in the Journal of Neuropsychology (British Psychological Society publication) now suggests that people with PSP experience more severe and extensive cognitive impairments than those with PD early on.
The study indicates that patients with PSP experience more severe ...
2014-10-10
The initial benefits of an outpatient antimicrobial stewardship intervention designed to reduce the rate of inappropriate antibiotic prescriptions were lost after discontinuation of audit and feedback to clinicians, according to a study published in JAMA. The study is being released early online to coincide with the IDWeek 2014 meeting.
Antibiotics are the most frequently prescribed medications for children; most are prescribed for outpatient acute respiratory tract infections. Because antibiotic prescribing is often inappropriate, Jeffrey S. Gerber, M.D., Ph.D., of ...
2014-10-10
The so-called Signal Transducers and Activators of Transcription, or STATs, are key components of many different signalling pathways. Not surprisingly, then, when something goes wrong with their regulation the consequences can be severe and many types of cancer are known to be associated with increased activities of one or more STAT protein. STAT3 is a frequent culprit and is often found to be activated in tumour cells.
Considerable efforts are going into developing inhibitors of STAT3 for use in cancer therapy but it is unclear whether these will turn out to be suitable ...
2014-10-10
New research out of Queen's University could give insight into what terrorists are thinking. Professor David Skillicorn (School of Computing) analyzed language used in two jihadist magazines to gain intelligence about terrorist strategy.
He examined the language used in Inspire, an online magazine reportedly published by al-Qaida in the Arabian Peninsula, which aims to increase the availability of their message, and the Islamic State News published by ISIS. Inspire has attracted attention because of its goal of attracting lone-wolf attacks in Western countries.
"The payoff ...
2014-10-10
The immunosuppressive drug fingolimod (trade name: Gilenya) was approved for an expanded therapeutic indication in May 2014: It is now also available for adults with highly active relapsing remitting multiple sclerosis (RRMS) who had received other pretreatment than interferon beta (IFN-β). In an early benefit assessment pursuant to the Act on the Reform of the Market for Medicinal Products (AMNOG), the German Institute for Quality and Efficiency in Health Care (IQWiG) examined whether the drug offers an added benefit over the appropriate comparator therapy in this ...
2014-10-10
A previously unknown mechanism through which the brain produces new nerve cells after a stroke has been discovered at Lund University and Karolinska Institute in Sweden. The findings have been published in the journal SCIENCE.
A stroke is caused by a blood clot blocking a blood vessel in the brain, which leads to an interruption of blood flow and therefore a shortage of oxygen. Many nerve cells die, resulting in motor, sensory and cognitive problems.
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2014-10-10
A novel technique which reduces image degradation caused by respiratory motion during a PET scan was developed in a recent study at the University of Eastern Finland. PET scanning is routinely used to detect cancer and heart conditions. The new technique presented in the PhD thesis of Tuomas Koivumäki, MSc (Tech.), is based on bioimpedance measurement and it allows for image reconstruction at a specific phase of the patient's breathing pattern. This, in turn, makes it possible to reduce image degradation caused by motion.
In the future, the newly developed technique ...
2014-10-10
New Orleans, LA – A special study using data from LSU Health New Orleans School of Public Health's Louisiana Tumor Registry has found that colorectal cancer incidence rates in the Louisiana Acadian parishes are among the highest in the United States. This study appears to be the first to identify a high rate of cancer in a large, regional, US founder population, raising the possibility of a genetic predisposition. Alternatively, an unidentified, robust environmental risk factor may be present. The paper is published online in Clinical and Translational Gastroenterology, ...
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[Press-News.org] Dangerous blood clots: A serious global problem
