(Press-News.org) New Rochelle, NY, December 15, 2014-Adiponectin, a collagen-like protein secreted by fat cells, derives from the ADIPOQ gene. Variations in this gene may increase risk for type 2 diabetes, cardiovascular disease, and various cancers. A new study that links specific variations in the ADIPOQ gene to either higher or lower colorectal cancer risk is published in Genetic Testing and Molecular Biomarkers, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available on the Genetic Testing and Molecular Biomarkers website until January 11, 2014.
Xin Guo, First Affiliated Hospital of Harbin Medical University, China, and Jiaqi Liu, Liuping You, Gang Li, Yuenan Huang, and Yunlong Li, Second Affiliated Hospital of Harbin Medical University, explored the relationship between two polymorphisms in the adiponectin gene and the risk of colorectal cancer in the article "Association Between Adiponectin Polymorphisms and the Risk of Colorectal Cancer." They also showed that these genetic variations may interact with environmental factors, such as red meat intake, to affect cancer risk.
"This paper suggests that adiponectin gene sequence may have significant prognostic value for colorectal cancer," says Kenneth I. Berns, MD, PhD, Editor-in-Chief of Genetic Testing and Molecular Biomarkers, and Director of the University of Florida's Genetics Institute, College of Medicine, Gainesville, FL.
INFORMATION:
About the Journal
Genetic Testing and Molecular Biomarkers is an authoritative peer-reviewed journal published monthly online with Open Access options and in print that reports on all aspects of genetic testing, including molecular and biochemical based tests and varied clinical situations; ethical, legal, social, and economic aspects of genetic testing; and issues concerning effective genetic counseling. Genetic Testing and Molecular Biomarkers is the official journal of Genetic Alliance. Complete tables of content and a free sample issue may be viewed on the Genetic Testing and Molecular Biomarkers website.
About the Publisher
Mary Ann Liebert, Inc., publishers is a privately held, fully integrated media company known for establishing authoritative peer-reviewed journals in many promising areas of science and biomedical research, including Human Gene Therapy and OMICS: A Journal of Integrative Biology. Its biotechnology trade magazine, Genetic Engineering & Biotechnology News (GEN), was the first in its field and is today the industry's most widely read publication worldwide. A complete list of the firm's 80 journals, books, and newsmagazines is available on the Mary Ann Liebert, Inc., publishers website.
Since August 2014, aflibercept (trade name Eylea) has been available also for patients with visual impairment due to diabetic macular oedema (DMO). The German Institute for Quality and Efficiency in Health Care (IQWiG) examined in a dossier assessment whether this drug offers an added benefit over the appropriate comparator therapy.
According to the findings, an added benefit in this therapeutic indication is not proven: The data showed no relevant differences between the treatment groups for patients in whom the fovea centralis is also affected. The drug manufacturer ...
Squid, what is it good for? You can eat it and you can make ink or dye from it, and now a Penn State team of researchers is using it to make a thermoplastic that can be used in 3-D printing.
"Most of the companies looking into this type of material have focused on synthetic plastics," said Melik C. Demirel, professor of engineering science and mechanics. "Synthetic plastics are not rapidly deployable for field applications, and more importantly, they are not eco-friendly."
Demirel and his team looked at the protein complex that exists in the squid ring teeth (SRT). ...
The team from The University of Nottingham and Queen Mary University of London, spent ten months studying to the ways cows communicate with their young, carefully examining acoustic indicators of identity and age.
They identified two distinct maternal 'calls'. When cows were close to their calves, they communicated with them using low frequency calls. When they were separated - out of visual contact - their calls were louder and at a much higher frequency.
Calves called out to their mothers when they wanted to start suckling. And all three types of calls were individualised ...
ANN ARBOR--It's not unusual for people to use war metaphors such as "fight" and "battle" when trying to motivate patients with cancer.
But a new University of Michigan study indicates that using those words can have an unintended negative effect.
David Hauser, a U-M doctoral student in psychology, and colleague Norbert Schwarz of the University of Southern California, found in three studies that exposure to metaphoric language relating cancer to an enemy significantly lessens the extent to which people consider cancer-prevention behaviors.
"Hearing metaphoric utterances ...
WASHINGTON D.C., Dec. 15, 2014--Cervical cancer is, in many ways, a shining example of how successful the war on cancer can be. Thanks largely to the advent of Pap smear screening, U.S. cervical cancer deaths decreased dramatically, by more than 60 percent, between 1955 and 1992. In the last two decades, better treatment outcomes and more powerful imaging techniques have steadily pushed 5-year survival rates ever higher. The latest weapons in modern medicine's arsenal are two new vaccines that were recently approved by the U.S. Food and Drug Administration for preventing ...
Airports are now subject to careful security surveillance, but many coastal towns and ports are not; they often lack radar installations to keep track of small boats, meaning terrorists could easily use speedboats to approach the coastline and bring explosives on land. Now, researchers at the Fraunhofer Institute for Communication, Information Processing and Ergonomics FKIE in Bonn developed a passive surveillance system for littoral regions based on mobile radio illumination called Passive Coherent Location (PCL). It passively employs the continuous radio signals emitted ...
Leipzig. New flooring in the living environment of pregnant women significantly increases the risk of infants to suffer from respiratory diseases in their first year of life. This is the result of a study carried out by the Helmholtz Centre for Environmental Research (UFZ) and the "St Georg" Municipal Hospital, which demonstrates that exposure to volatile organic compounds in the months before and after birth induces breathing problems in early childhood . The scientists therefore recommend that redecoration should be avoided during pregnancy or in the first year of children's ...
Children who skip main meals are more likely to have excess body fat and an increased cardiometabolic risk already at the age of 6 to 8 years, according to a Finnish study. A higher consumption of sugary drinks, red meat and low-fat margarine and a lower consumption of vegetable oil are also related to a higher cardiometabolic risk. "The more of these factors are present, the higher the risk," says Ms Aino-Maija Eloranta, MHSc, who presented the results in her doctoral thesis at the University of Eastern Finland.
The dietary habits, eating behaviour and dietary determinants ...
ANN ARBOR, Mich. - Most parents agree their children should be ready to move out of the pediatrician's office into adult-focused care by age 18 - but just 30 percent actually make that transition by that age, according to the University of Michigan C.S. Mott Children's Hospital National Poll on Children's Health.
As health care becomes more complex, it's difficult for teens to shift from relying on their parents to taking on their own health care needs.
The C.S. Mott National Poll on Children's Health asked a national sample of parents of adolescents and young adults ...
Cities like Miami are all too familiar with hurricane-related power outages. But a Johns Hopkins University analysis finds climate change will give other major metro areas a lot to worry about in future storms.
Johns Hopkins engineers created a computer model to predict the increasing vulnerability to hurricanes of power grids in major cities on or relatively near the Atlantic and Gulf coasts. They factored historic hurricane information in with plausible scenarios for future storm behavior, given a global rise in average temperatures. With that data, the team could pinpoint ...
