(Press-News.org) Drug users who do not benefit from conventional treatments for heroin addiction should be able to access the drug through the health system, urges a Canadian expert in The BMJ today.
Standard treatments for heroin drug addiction include detoxification, abstinence programmes and methadone maintenance, but there is a subgroup of patients for whom these do not work.
As doctors can provide no effective treatments for these patients, many will remain "outside the healthcare system" and there is "overwhelming" evidence that they will relapse into using illicit heroin and "suffer immeasurably" while costing society a "fortune," explains Martin T Schechter, Professor, School of Population and Public Health, Faculty of Medicine, University of British Columbia, Vancouver, Canada.
Illicit heroin is a dangerous street drug because its dose and purity are unknown and users face the risk of overdose and death. Because the drug is illegal, many users engage in unsafe practices, for example, using contaminated syringes that increase the risk of life threatening infections such as HIV and hepatitis, and its use often leads to crime and sex work.
Many users are often in and out of hospitals and prisons for these reasons, he explains, adding that they can be "deeply affected by the illness of the addiction and its consequences."
But heroin assisted treatments should be offered to this vulnerable group of patients, he argues, because they have been shown to improve outcomes, reduce harm, lower societal cost and make savings for the healthcare system.
Currently, this type of treatment is not offered following regulations put in place by the Canadian government in 2014 although a small group of participants are being given the drug after benefiting from it in a successful clinical trial.
Schechter notes six randomised controlled trials that found heroin assisted treatment to be more effective than standard treatments for such patients, and the recent Cochrane Collaboration review that concluded that it can help to decrease illicit substance use, criminal activity, incarceration and possibly reduce mortality and increase compliance with treatment.
In addition, he explains that while the direct cost of heroin assisted treatment is four times that of traditional treatments, it still works out to be cheaper when accounting for all associated costs when compared to other interventions.
For example, a trial in the Netherlands showed that heroin assisted therapy made overall savings of around € 13,000 (£9530; $14,100) per patient per year when compared to methadone, even when taking into account the direct cost of treatment.
Other research carried out by Schechter demonstrated better outcomes at a lower societal cost compared to methadone maintenance while British researchers found that heroin assisted therapy was more cost effective than oral methadone.
"Treatments like this represent the holy grail of medical research seeking to support a sustainable health system: they achieve better outcomes at lower overall cost," he argues.
And such savings could be used in addiction prevention programmes and other important priorities, he notes, adding that "the key question is not whether we can afford this new treatment, but whether we can afford the status quo."
Conventional treatments should remain the first preference for patients with heroin addiction, but if these do not work, diamorphine should be prescribed to patients by doctors at specialized clinics to ensure safety, he concludes.
INFORMATION:
Citrus fruits -- delectable oranges, lemons, limes, kumquats and grapefruits -- are among the most important commercially cultivated fruit trees in the world, yet little is known of the origin of the citrus species and the history of its domestication.
Now, Joaquin Dopazo et al, in a new publication in the journal Molecular Biology and Evolution, have performed the largest and most detailed genomic analysis on 30 species of Citrus, representing 34 citrus genotypes, and used chloroplast genomic data to reconstruct its evolutionary history.
Overall, the results confirm ...
A team led by Case Western Reserve researchers has identified a potentially powerful approach to lowering relapse rates among the ranks of those addicted to illegal drugs or alcohol.
In a study of nearly 200 teenagers admitted to a residential treatment center in the northeastern United States, psychiatry professor Maria Pagano, PhD, confirmed both the prevalence of social anxiety issues among them as well as the benefits of measures designed to alleviate social distress. These findings were posted online this month in the journal Alcoholism: Clinical and Experimental ...
UPTON, NY - The Relativistic Heavy Ion Collider (RHIC, http://www.bnl.gov/rhic/), a powerful particle accelerator for nuclear physics research at the U.S. Department of Energy's Brookhaven National Laboratory, just shattered its own record for producing polarized proton collisions at 200-giga-electron-volt (GeV) collision energy. In the experimental run currently underway at this two-ringed, 2.4-mile-circumference particle collider, accelerator physicists are now delivering 1200 billion of these subatomic smashups per week-more than double the number routinely achieved ...
While the risk of alcohol-related liver cirrhosis is known to increase with heavy drinking, a number of people who drink large quantities of alcohol seem to escape developing the disease. This variation in susceptibility may be due to several factors beyond quantity such as genetics, gender, and obesity. A preliminary clinical analysis of hundreds of drinkers with and without alcoholic cirrhosis has found that affected individuals often report a father with alcohol problems who had died from liver disease, which underscores the heritability of this disease.
Results will ...
The prefrontal cortex (PFC) and amygdala (AMG) are brain regions that not only referee cognitive functions and emotional states, but also contribute to the reinforcing effects of alcohol and tobacco. Researchers already knew that alcohol and tobacco use can modulate cytochrome P450 expression in the liver and other tissues, but little is known about the effects of alcohol and tobacco on P450s in the human AMG. A new study focusing on two CYP2 enzymes that metabolize drugs and endogenous compounds has found that chronic drinking is associated with higher CYP2E1 and CYP2U1 ...
This century's increase in addiction issues among U.S. youth may be related to their developmental need to fit in, particularly youth with social anxiety disorder (SAD), which could exacerbate the drink/trouble cycle. In addition, socially anxious youths may avoid participating in therapeutic activities during treatment for fear of negative peer appraisal. A study of the influence of SAD on clinical severity at intake, peer helping in Alcoholics Anonymous (AA) during treatment, and subsequent outcomes has found that almost half of the patients entering treatment had a persistent ...
Cannabis is the most commonly used drug among adults who drink, besides tobacco, yet no study has directly compared those who use cannabis and alcohol simultaneously, or at the exact same time, versus those who use both separately and on a regular basis. A new study looks at the relationship between marijuana and alcohol use, finding that simultaneous users had double the odds of drunk driving, social consequences, and harms to self.
Results will be published in the May 2015 online-only issue of Alcoholism: Clinical & Experimental Research and are currently available ...
WASHINGTON, DC - A new study suggests that an investigational drug for multiple sclerosis (MS) may repair myelin, the fatty material that protects nerves and is damaged in MS, according to a study released today that will be presented at the American Academy of Neurology's 67th Annual Meeting in Washington, DC, April 18 to 25, 2015.
"This study, for the first time, provides biological evidence of repair of damaged myelin in the human brain, and advances the field of neuro-reparative therapies," said study lead author Diego Cadavid, MD, with Biogen in Cambridge, Mass., ...
Divorced women suffer heart attacks at higher rates than women who are continuously married, a new study from Duke Medicine has found. A woman who has been through two or more divorces is nearly twice as likely to have a heart attack when compared to their stably-married female peers, according to the findings.
Even among women who remarry after the stress of divorce, their heart attack risk remains elevated according to the study published in Circulation: Cardiovascular Quality and Outcomes, a journal of the American Heart Association.
"Divorce is a major stressor, ...
New York, NY -- It has been called a pioneering strategy for treating opioid addiction, and has already been adopted in a small yet growing number of jails and prisons in the United States. Now, a clinical trial published in the journal Addiction by researchers at NYU Langone Medical Center finds that the extended-release medication naltrexone (XR-NTX) is associated with a significant decline in relapse rates for a group of mostly heroin-dependent men after their release from New York City jails.
The NYU Langone researchers say that their study is the only randomized ...