(Press-News.org) Cardiologists from the Mayo Clinic performed sheathless transradial percutaneous coronary intervention (PCI) to remedy complex lesions, achieving a 90% success rate with no radial complications. Standard guiding catheters were used during the procedure. Details of this novel approach—overcoming the last hurdle to greater adoption of transradial PCI in the U.S.—are published in the December issue of Catheterization and Cardiovascular Intervention, the official journal of The Society for Cardiovascular Angiography and Interventions.
PCI, commonly known as angioplasty, is a procedure used to open narrowed or blocked coronary arteries. According to the National Heart Lung and Blood Institute, angioplasty is performed on more than one million Americans each year. During the procedure, cardiac interventionists make a small incision, threading a catheter into the femoral artery in the groin or through the radial artery in the wrist, to access the blockage in the heart. The latter approach, called transradial angioplasty, is increasing in use due to quick patient recovery and lower complications at the access site. However, a major limitation of transradial PCI is the inability to use large guiding catheters because of the small size of the radial artery.
To explore this issue, Charanjit Rihal, MD, FSCAI, and colleagues from the Mayo Clinic performed transradial PCI using a sheathless technique with standard guiding catheters. The team identified ten patients who had transradial angioplasty for stable angina (60%) and acute coronary syndrome (40%) between September 2009 and March 2010. Treatment was attempted on 15 vessels and bifurcation (complex) lesions were present in six patients.
While current medical evidence report use of guiding catheters with hydrophilic coating and long central dilators during sheathless transradial PCI; these devices are currently not available in the U.S. In the current study, all procedures were performed using 7 Fr (six patients) or 8 Fr (four patients) Vista Brite Tip® guiding catheters which are non-hydrophilic coated.
"We showed the safety and feasibility of performing complex PCI through large-bore guiding catheters from the radial artery using a sheathless technique. This affords patients all the benefits of radial access for even the most complex coronary procedures," said Dr. Rihal. The series results showed PCI was successful in all but one patient who had a completely obstructed obtuse marginal artery that could not be crossed. One minor coronary complication was reported—a small vessel dissection within the lesion of interest which was covered with a stent. This patient was asymptomatic and dismissed in good health after one night of observation.
Furthermore, no deaths occurred during the follow-up period (median of 27 days), and researchers reported no episodes of radial artery spasm upon removal of the guide or any post procedure occlusions in the radial artery. Cross-over to the femoral artery was not needed in any of the cases. "Sheathless transradial PCI using standard large-bore guiding catheters is a safe and effective method for treatment of complex lesions," concluded Dr. Rihal.
INFORMATION:
Media Alert
In response to a recent member survey showing that a lack of formal training opportunities has been the primary obstacle for the adoption of the transradial PCI in the U.S., the Society for Cardiovascular Angiography and Interventions (SCAI) has launched a series of one-day education symposia on transradial interventions. The initial program in this series held on November 5th in Boston was an early sell-out, confirming this survey data.
The next program in this series will be the SCAI Transradial Interventional Program (TRIP) in Philadelphia on January 15, and full enrollment is again expected. More information on this program - including registration - is available online at www.SCAI.org/TRIP. Media interested in attending this event should contact Kathy Boyd David at kbdavid@scai.org.
This study is published in Catheterization and Cardiovascular Interventions. Media wishing to receive a PDF of the article may contact healthnews@wiley.com.
Full citations: "Sheathless Transradial Intervention Using Standard Guide Catheters." Aaron M. From, Rajiv Gulati, Abhiram Prasad and Charanjit S. Rihal. Catheterization and Cardiovascular Interventions; Published Online: October 7, 2010 (DOI: 10.1002/ccd.22742); Print Issue Date: December 2010. http://onlinelibrary.wiley.com/doi/10.1002/ccd.22742/abstract.
Catheterization and Cardiovascular Interventions is the official journal of The Society for Cardiovascular Angiography and Interventions. This international journal covers the broad field of cardiovascular diseases. Subject material includes basic and clinical information that is derived from or related to invasive and interventional coronary or peripheral vascular techniques. The journal focuses on material that will be of immediate practical value to physicians providing patient care in the clinical laboratory setting. To accomplish this, the journal publishes Preliminary Reports and Work In Progress articles that complement the traditional Original Studies, Case Reports, and Comprehensive Reviews. Perspective and insight concerning controversial subjects and evolving technologies are provided regularly through Editorial Commentaries furnished by members of the Editorial Board and other experts. Articles are subject to double-blind peer review and complete editorial evaluation prior to any decision regarding acceptability. For more information, please visit http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)1522-726X.
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