PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

As death rates drop, nonfatal diseases and injuries take a bigger toll on health globally

In every country, back pain and depression are among the leading causes of years lived with disability; mental and substance abuse disorders cause one-fifth of disabling conditions

2015-06-08
(Press-News.org) SEATTLE -- People across the world are living longer but spending more time in ill health as rates of nonfatal diseases and injuries - including diabetes and hearing loss - decline more slowly than death rates, according to a new analysis of 301 diseases and injuries in 188 countries.

Using a measurement known as years lived with disability, or YLDs, researchers from around the world quantified the impact of health problems that impair mobility, hearing, or vision, or cause pain in some way but aren't fatal. In 2013, low back pain and major depressive disorder were among the 10 leading causes of YLDs in every country. Other leading causes globally included neck pain, anxiety disorders, migraine headaches, and diabetes. The leading causes of years lived with disability have remained largely the same during this period, but they are taking an increased toll on health due to population growth and aging.

YLDs per person increased in 139 of 188 countries between 1990 and 2013, meaning that more people are spending more time in poor health. Musculoskeletal disorders, combined with fractures and soft tissue injuries, accounted for one-fifth of YLDs globally in 2013, ranging from 11% in Mali to 30% in South Korea. Mental and substance abuse disorders also caused 20% of YLDs globally, ranging from 15% in Germany to 37% in Qatar.

"Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013" is the first study to examine the extent, pattern, and trends of nonfatal health loss across countries. Published in The Lancet on June 8, the study was conducted by an international consortium of researchers working on the Global Burden of Disease project and led by the Institute for Health Metrics and Evaluation (IHME) at the University of Washington.

"Many countries around the world have made great progress in addressing fatal diseases, but nonfatal illnesses pose the next major threat in terms of disease burden," said Professor Theo Vos of IHME, the study's lead author. "This need to meet the challenge of nonfatal diseases and injuries only becomes more urgent as the population increases and people live longer."

Between 1990 and 2013, YLDs increased globally from 537.6 million in 1990 to 764.8 million in 2013 for both sexes. Men and women around the world share the same leading causes of YLDs, with the exception of schizophrenia as a leading cause for men and other musculoskeletal disorders for women. Musculoskeletal disorders, mental and substance use disorders, neurological disorders, and chronic respiratory conditions were the main drivers of YLDs in 2013. The disease burdens of both low back pain and depression have increased more than 50% since 1990.

Researchers found that as people aged they experienced a greater number of ailments resulting from nonfatal diseases and injuries. Many people also suffered from multiple conditions at the same time. The number of people who suffered from 10 or more ailments increased by 52%. And it's not just the elderly who are affected. Although the impact of YLDs increases with age, of the 2.3 billion people who suffered from more than five ailments, 81% of them were younger than 65 years old.

A relatively small number of diseases have a massive impact, researchers found. Just two acute diseases - affecting people for less than three months - caused more than 20 billion new cases of disease globally in 2013: upper respiratory infections (18.8 billion) and diarrheal diseases (2.7 billion). And just eight causes of chronic diseases - affecting people for three months or longer - impacted more than 10% of the world's population. These included tension-type headaches and iron-deficiency anemia.

In 2013, war and conflict was a leading cause of YLDs in several countries as well, including El Salvador, Lebanon, Guatemala, Peru, and Syria. In three countries - Cambodia, Nicaragua, and Rwanda - war was the top cause of years lived with disability. Other notable causes of YLDs in different regions included falls (Central Europe), asthma (a top-10 cause in many Latin American countries), and opioid dependence (a top-five cause in several Middle Eastern countries). Nonfatal conditions are not yet becoming the dominant source of disease burden in sub-Saharan Africa as they are in other parts of the world, but their impact has grown since 1990.

"What ails you isn't necessarily what kills you," said IHME Director Dr. Christopher Murray. "As nonfatal illnesses and related ailments affect more people of all ages, countries must look closely at health policies and spending to target these conditions."

Leading causes of YLDs globally for both sexes in 2013

Low back pain Major depressive disorder Iron-deficiency anemia Neck pain Age-related and other hearing loss Diabetes mellitus Migraine Chronic obstructive pulmonary disease Anxiety disorders Other musculoskeletal disorders

Leading causes of YLDs globally for men in 2013

Low back pain Major depressive disorder Age-related and other hearing loss Iron-deficiency anemia Diabetes mellitus Neck pain Chronic obstructive pulmonary disease Migraine Anxiety disorders Schizophrenia

Leading causes of YLDs globally for women in 2013

Low back pain Major depressive disorder Iron-deficiency anemia Neck pain Migraine Other musculoskeletal disorders Anxiety disorders Age-related and other hearing loss 9 Diabetes mellitus 10 Chronic obstructive pulmonary disease

INFORMATION:

Download the study at http://www.healthdata.org/research-article/global-regional-and-national-incidence-prevalence-and-years-lived-disability-2013.

The Institute for Health Metrics and Evaluation (IHME) is an independent global health research organization at the University of Washington that provides rigorous and comparable measurement of the world's most important health problems and evaluates the strategies used to address them. IHME makes this information widely available so that policymakers have the evidence they need to make informed decisions about how to allocate resources to best improve population health.

Media contact:

Rhonda Stewart, IHME
stewartr@uw.edu
+1-206-897-2863



ELSE PRESS RELEASES FROM THIS DATE:

New survey: Only about half of men can remember their last medical check-up

New survey: Only about half of men can remember their last medical check-up
2015-06-08
Clermont, Florida. (June 8, 2015) - A new national survey about men and their cars, commissioned by Orlando Health, found that more than 80 percent of men could remember the make and model of their first car, but only about half could remember the last time they went to the doctor for a check-up. The survey of approximately 1,000 men is being released in conjunction with the start of the Drive For Men's Health, a cross-country event where two of the top men's health surgeons in the US will travel 6,008 miles to promote awareness on various men's health topics. ...

New study describes cancer's cheating ways

New study describes cancers cheating ways
2015-06-08
Cancer cells share certain traits with anti-social members of human society. They shirk community responsibilities and engage in behavior aimed at fulfilling their selfish needs at the expense of the greater good. In a new study, Athena Aktipis, a researcher at Arizona State University's Biodesign Institute, along with her international colleagues, explore the ways in which cancers bypass the protective mechanisms used by multicellular forms to ensure their survival and wellbeing. The paper identifies five foundations of multicellularity; maintenance factors present ...

Leaky pipes can allow contaminants into our drinking water

2015-06-08
The study, by engineers at the University of Sheffield, is the first to prove conclusively that contaminants can enter pipes through leaks and be transported through the pipe network. The pressure in mains water pipes usually forces water out through leaks, preventing anything else from getting in. But when there is a significant pressure drop in a damaged section of pipe, water surrounding the pipe can be sucked in through the hole. It had been assumed that only clean water from the leak would be sucked in, and that even if contaminants were sucked in these would ...

People want access to their own genomic data, even when uninterpretable

2015-06-08
Glasgow, United Kingdom: The largest study to date of attitudes towards the use of genomic information shows that the majority of people want access to results from genome sequencing, even if these are not directly related to the condition for which the analysis has been undertaken. This applies even when the data are not health-related or are simply 'raw', a researcher will tell the annual conference of the European Society of Human Genetics today (Monday). Dr Anna Middleton, a Principal Staff Scientist at the Wellcome Trust Sanger Institute, Cambridge, UK, will describe ...

Current mobile contracts damaging the environment, research finds

2015-06-08
Research published today in the journal the International Journal of Life Cycle Assessment has called for an overhaul of the way mobile devices are manufactured and contracted, in order to stop the harmful effects on the environment caused by current business models. Researchers from the University of Surrey analysed studies on the lifespan of mobile devices, from manufacture, use and disposal to see what impact each stage had on the environment. Through their investigation, they concluded that the current mobile business model, driven by frequent upgrades, is costing ...

Massachusetts General Hospital launches phase II trial of BCG vaccine to reverse type 1 diabetes

2015-06-07
A phase II clinical trial testing the ability of the generic vaccine bacillus Calmette-Guérin (BCG) to reverse advanced type 1 diabetes has received approval from the U.S. Food and Drug Administration (FDA). The approval of this trial, which will shortly begin enrolling qualified patients, was announced today at the 75th Scientific Sessions of the American Diabetes Association (ADA) by Denise Faustman, MD, PhD, director of the Massachusetts General Hospital (MGH) Immunobiology Laboratory and principal investigator of the study. The five-year trial will investigate ...

50 years of diabetes research and treatment

2015-06-06
BOSTON (June 6, 2015) - From how people test their glucose levels to how long they can expect to live, almost everything has changed over the past 50 years for Americans with diabetes. A special symposium held at the American Diabetes Association's 75th Scientific Sessions features a look back at what physicians and researchers have learned and how the lives of patients have changed during the past five decades. "There are things that have happened over the past 50 years that clearly make life a lot better for people," said Fred Whitehouse, MD, Division Head Emeritus ...

Novel genetic mutations may arise during early embryonic development

2015-06-06
Until now, de novo genetic mutations, alterations in a gene found for the first time in one family member, were believed to be mainly the result of new mutations in the sperm or eggs (germline) of one of the parents and passed on to their child. Researchers from The Netherlands have now succeeded in determining that at least 6.5% of de novo mutations occur during the development of the child (post-zygotic) rather than from the germline of a parent. The research is published today in the American Journal of Human Genetics*. Christian Gilissen, PhD, Assistant Professor ...

Discovery of new genetic mutation in aortic disease allows better diagnosis

2015-06-06
Glasgow, United Kingdom: Thoracic aortic aneurysm and dissection (TAAD), an enlargement or tearing of the walls of the aorta in the chest, is, together with abdominal aortic aneurysms, responsible for about 2% of all deaths in Western countries. The aorta is the largest artery in the body, and carries blood from the heart. About one out of every five patients with TAAD has a family member with the same disorder, therefore indicating a genetic cause. However, the relevant genetic mutations discovered so far only explain about 30% of all cases. Through the study of a large ...

Noninvasive prenatal testing: Effective, safe, preferred by parents

2015-06-06
Glasgow, United Kingdom: Non-invasive prenatal testing (NIPT) for Down's syndrome is feasible, acceptable to parents, and could be introduced into the National Health Service (NHS), UK researchers say. The results of a National Institute for Health Research (NIHR) study carried out by the first NHS laboratory to provide NIPT testing will be reported to the annual conference of the European Society of Human Genetics today (Saturday). Presenting her team's findings, Professor Lyn Chitty, from the UCL Institute of Child Health and Great Ormond Street Hospital, London, UK, ...

LAST 30 PRESS RELEASES:

Grant to support new research to address alcohol-related partner violence among sexual minorities

Biodiversity change amidst disappearing human traditions

New approaches to synthesize compounds for pharmaceutical research

Cohesion through resilient democratic communities

UC Santa Cruz chemists discover new process to make biodiesel production easier, less energy intensive

MD Anderson launches Institute for Cell Therapy Discovery & Innovation to deliver transformational new therapies

New quantum encoding methods slash circuit complexity in machine learning

New research promises an unprecedented look at how psychosocial stress affects military service members’ heart health

Faster measurement of response to antibiotic treatment in sepsis patients using Dimeric HNL

Cleveland Clinic announces updated findings in preventive breast cancer vaccine study

Intergenerational effects of adversity on mind-body health: Pathways through the gut-brain axis

Watch this elephant turn a hose into a sophisticated showering tool

Chimpanzees perform better on challenging computer tasks when they have an audience

New medical AI tool identifies more cases of long COVID from patient health records

Heat waves and adverse health events among dually eligible individuals 65 years and older

Catastrophic health expenditures for in-state and out-of-state abortion care

State divorce laws, reproductive care policies, and pregnancy-associated homicide rates

Emerging roles of high-mobility group box-1 in liver disease

Exploring the systematic anticancer mechanism in selected medicinal plants

University of Cincinnati researchers pen editorial analyzing present, future of emergency consent in stroke trials

Scarlet Macaw parents ‘play favorites,’ purposefully neglect younger chicks

One gene provides diagnoses for 30 patients whose condition was unexplained for years

Current practice and emerging endoscopic technology in the diagnosis of colorectal cancer

Decoding 17-beta-hydroxysteroid dehydrogenase 13: A multifaceted perspective on its role in hepatic steatosis and associated disorders

Key pathway leading to neurodegeneration in early stages of ALS identified

Ferroptosis in regulating treatment tolerance of digestive system tumors

A promising future in pancreatic incidentaloma detection

Stabilizing lithium-ion batteries: The vanadium touch

Innovative approaches to the surgical challenges in the management of gastroschisis

Mouse models for the study of liver fibrosis regression in vivo and ex vivo

[Press-News.org] As death rates drop, nonfatal diseases and injuries take a bigger toll on health globally
In every country, back pain and depression are among the leading causes of years lived with disability; mental and substance abuse disorders cause one-fifth of disabling conditions