PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Tamper-resistant opioids will not solve opioid addiction problem

2015-06-29
(Press-News.org) Tamper-resistant formulations of drugs will not solve the problems of opioid addiction and overdose, argues a commentary in CMAJ (Canadian Medical Association Journal).

Governments in Canada and the United States are promoting tamper-resistant drugs, which are more difficult to crush, snort or inject, to prevent addiction and other harms. Opioid users may tamper with prescribed tablets, capsules or patches for a faster "high."

"Misuse and diversion of opioids is a complex problem that requires a comprehensive solution; simply substituting one formulation for another will not work," writes Dr. Pamela Leece, Dalla Lana School of Public Health, University of Toronto, with coauthors.

Canada and the US are the highest per-capita users of narcotics in the world. Oxycodone prescriptions in Ontario rose 850% from 1991 to 2007, and deaths from opioids doubled between 1991 and 2004. Although some studies indicate that tamper-resistant formulations of oxycodone may have reduced use of the drug,, there is increasing evidence that the overall number of deaths has not decreased. People who are addicted to opioids will use other types of opioids as well as heroin, which can cause lethal overdoses.

"Regulations requiring tamper resistance represent an expensive, technical approach that is influenced by pharmaceutical interests and cannot solve the opioid crisis. An evidence-based, multifaceted strategy is needed -- one that has real potential to curb opioid-related harms at a population level," the authors conclude.

INFORMATION:



ELSE PRESS RELEASES FROM THIS DATE:

Automatic bug repair

2015-06-29
At the Association for Computing Machinery's Programming Language Design and Implementation this month, MIT researchers presented a new system that repairs dangerous software bugs by automatically importing functionality from other, more secure applications. Remarkably, the system, dubbed CodePhage, doesn't require access to the source code of the applications whose functionality it's borrowing. Instead, it analyzes the applications' execution and characterizes the types of security checks they perform. As a consequence, it can import checks from applications written ...

New IOM report: Wait times for health care services differ greatly throughout US

2015-06-29
WASHINGTON - Tremendous variability in wait times for health care appointments exists throughout the U.S., ranging from same day service to several months, says a new report from the Institute of Medicine. However, there is currently an opportunity to develop "systems-based approaches" -- similar to systems-based engineering approaches applied successfully in industries beyond health care -- that aim to provide immediate engagement of a patient's concern at the point of initial contact and can be used in in-person appointments as well as alternatives such as team-based ...

New nanogenerator harvests power from rolling tires

New nanogenerator harvests power from rolling tires
2015-06-29
MADISON - A group of University of Wisconsin-Madison engineers and a collaborator from China have developed a nanogenerator that harvests energy from a car's rolling tire friction. An innovative method of reusing energy, the nanogenerator ultimately could provide automobile manufacturers a new way to squeeze greater efficiency out of their vehicles. The researchers reported their development, which is the first of its kind, in a paper published May 6, 2015, in the journal Nano Energy. Xudong Wang, the Harvey D. Spangler fellow and an associate professor of materials ...

Scientists develop more accurate whole genome variant discovery and interpretation

2015-06-29
NEW YORK -- June 29, 2015 /Press Release/ -- Scientists from the Icahn School of Medicine at Mount Sinai have developed a new approach to build nearly complete genomes by combining high-throughput DNA sequencing with genome mapping. The methodology enabled researchers to detect complex forms of genomic variation, critically important for their association with human disease, but previously difficult to detect. The study was published today in Nature Methods, and is a collaboration with scientists at European Molecular Biology Lab, Weill Cornell Medical College, Cold Spring ...

Wind effect following team car can help time trial rider win Tour prologue

Wind effect following team car can help time trial rider win Tour prologue
2015-06-29
Will next Saturday's Tour de France prologue in Utrecht get the winner it deserves? New aerodynamic research at Eindhoven University of Technology (TU/e) shows that riders in a time trial can save vital seconds by riding closer to the following team car. Over a short distance like the prologue of the Tour de France, that can save as much as 6 seconds: enough to make the difference between winning and losing. On longer time trials and events like world championships, the effect can even add up to tens of seconds. Which is why aerodynamics professor Bert Blocken is advising ...

Up, up and away, in the name of science education

2015-06-29
US researchers extol the virtues of high-altitude balloons for science education in a research paper published in the International Journal of Learning Technology. According to Jeremy Straub of the University of North Dakota in Grand Forks, "High-altitude balloons can carry student and scientific payloads to the boundaries of space." This, he suggests, gives students the opportunity to carry out experiments in a cold, near-vacuum, higher-radiation environment at such very high altitudes. "In the process, students experience the awe of space exploration as, through their ...

Experts present new knowledge on bone tissue and its role in bone strength or weakness

2015-06-29
Nyon, Switzerland - June 29, 2015 While there is good understanding of how bone mass, and more recently bone architecture, affects fracture risk, far less is known about the material properties of bone, or how these can impart resilience or fragility to the skeleton. This is changing thanks to the development of new state-of-the-art imaging and other technologies which now allow researchers to gain new insights into the different material properties of bone and their role in bone fragility. Bringing together eight invited contributions by the field's leading experts, ...

Scoring system can help trauma centers improve care during surges in trauma cases

2015-06-29
CHICAGO (June 29, 2015): A scoring system that can identify periods of high activity and increased trauma patient deaths in hospital emergency rooms may help hospitals better prepare for surges in trauma patient volume that come with catastrophic events like the Boston Marathon bombing (April 2013) or disasters like the Amtrak train crash (May 2015) in Philadelphia. Trauma surgeon Peter C. Jenkins, MD, MSc, and a team of investigators from Indiana University and multiple centers developed the scoring system, called the Trauma Surge Index (TSI). They reported their observations ...

The chemistry of grilling (video)

The chemistry of grilling (video)
2015-06-29
WASHINGTON, June 29, 2015 -- If you're firing up the barbecue this week for an Independence Day cookout, you don't want to miss this week's Reactions video. We've got chemistry knowledge that will impress your guests like, "Why is red meat red?" You'll also learn about the amazing Maillard reaction that turns that red meat into a delicious grilled brown. We also settle, once and for all, the age-old debate of gas vs. charcoal. It's all in our latest video: https://youtu.be/RqUEh-B-U-k. Subscribe to the series at http://bit.ly/ACSReactions, and follow us on Twitter @ACSreactions ...

Rare gene variant associated with middle ear infections

2015-06-29
HOUSTON, June 29 -- Many parents have heard the night-time cry of "my ear hurts." For some children, this might happen frequently beginning in infancy and even persist into adulthood. An international consortium led by those at Baylor College of Medicine may have taken the first step on the road to understanding why only some people get frequent painful or chronic middle ear infections. The culprit may be rare genetic variants in a gene called A2ML1. A report on their work appears online in the journal Nature Genetics. In studies led by Dr. Regie Lyn P. Santos-Cortez, ...

LAST 30 PRESS RELEASES:

LIGO-Virgo-KAGRA detect most massive black hole merger to date

Lonely adults may have a higher risk of diabetes

Intermittent energy restriction may improve outcomes in people with obesity and type 2 diabetes

Grandfather’s environmental chemical exposures may influence when girls get first period

Early-life exposure to endocrine-disrupting chemicals may fuel food preferences

Age at woman’s first period can offer clues about long-term health risks

AI-powered application enables clinicians to diagnose endocrine cancers faster and more accurately

Obesity-associated cancers tripled nationwide over past two decades

Consuming certain sweeteners may increase risk of early puberty

Experts suggest screening women with diabetes for intent to conceive at every doctor visit

Osteoporosis treatment benefits people older than 80

Consuming more protein may protect patients taking anti-obesity drug from muscle loss

Thyroid treatment may improve gut health in people with hypothyroidism

Combination of obesity medication tirzepatide and menopause hormone therapy fuels weight loss

High blood sugar may have a negative impact on men’s sexual health

Emotional health of parents tied to well-being of children with growth hormone deficiency

Oxytocin may reduce mood changes in women with disrupted sleep

Mouse study finds tirzepatide slowed obesity-associated breast cancer growth

CMD-OPT model enables the discovery of a potent and selective RIPK2 inhibitor as preclinical candidate for the treatment of acute liver injury

Melatonin receptor 1a alleviates sleep fragmentation-aggravated testicular injury in T2DM by suppression of TAB1/TAK1 complex through FGFR1

Single-cell RNA sequencing reveals Shen-Bai-Jie-Du decoction retards colorectal tumorigenesis by regulating the TMEM131–TNF signaling pathway-mediated differentiation of immunosuppressive dendritic ce

Acta Pharmaceutica Sinica B Volume 15, Issue 7 Publishes

New research expands laser technology

Targeted radiation offers promise in patients with metastasized small cell lung cancer to the brain

A high clinically translatable strategy to anti-aging using hyaluronic acid and silk fibroin co-crosslinked hydrogels as dermal regenerative fillers

Mount Sinai researchers uncover differences in how males and females change their mind when reflecting on past mistakes

CTE and normal aging are difficult to distinguish, new study finds

Molecular arms race: How the genome defends itself against internal enemies

Tiny chip speeds up antibody mapping for faster vaccine design

KTU experts reveal why cultural heritage is important for community unity

[Press-News.org] Tamper-resistant opioids will not solve opioid addiction problem