NCI awards SPORE grant to multiple myeloma research team from Mayo Clinic Cancer Center
2015-08-31
(Press-News.org) ROCHESTER Minn. -- A team of Mayo Clinic Cancer Center scientists has been awarded a Specialized Program of Research Excellence (SPORE) grant in multiple myeloma from the National Cancer Institute. The Mayo Clinic Cancer Center is one of only three cancer centers to receive a SPORE grant for multiple myeloma cancer research.
MULTIMEDIA ALERT: Video and audio are available for download on the Mayo Clinic News Network.
"With project leaders from Mayo campuses in Arizona, Rochester and Florida, our SPORE team will study the genetic basis for myeloma, develop novel viral and immunologic therapies, and optimize the use of existing therapies with a goal of controlling and eventually curing this deadly disease," says Leif Bergsagel, M.D., lead investigator. "Starting from the pioneering work of Robert Kyle, M.D., over the last half-century, the myeloma group at Mayo Clinic is one of the strongest in the world."
Renowned journalist and Mayo Clinic Trustee Tom Brokaw will serve as a patient advocate to the SPORE to represent the interests of patients with multiple myeloma and increase awareness of, and support for, myeloma research.
Multiple myeloma, a disease of bone marrow antibody secreting cells, is a devastating cancer that affects more than 20,000 new patients every year in the United States. While recent improvements in treatment have resulted in a more favorable outlook for patients, five-year survival rates remain low.
INFORMATION:
About Mayo Clinic Cancer Center
As a leading institution funded by the National Cancer Institute, the Mayo Clinic Cancer Center conducts basic, clinical and population science research, translating discoveries into improved methods for prevention, diagnosis, prognosis and therapy. For information on cancer clinical trials, call 1-855-776-0015 (toll-free).
About Mayo Clinic
Mayo Clinic is a nonprofit organization committed to medical research and education, and providing expert, whole-person care to everyone who needs healing. For more information, visit http://www.mayoclinic.org/about-mayo-clinic or http://newsnetwork.mayoclinic.org/.
ELSE PRESS RELEASES FROM THIS DATE:
2015-08-31
Satellite data from NOAA's GOES-East satellite was made into an animation that showed the demise of former Tropical Storm Erika as it neared eastern Cuba early on August 29.
At NASA's Goddard Space Flight Center in Greenbelt, Maryland, NASA/NOAA's GOES Project compiled three days' worth of imagery from NOAA's GOES-East satellite that showed the movement and changes in former Tropical Storm Erika from August 27 to August 29. The animation showed Erika move through the Leeward Islands and into the Eastern Caribbean Sea, as its center passed just south of Puerto Rico, then ...
2015-08-31
London, UK - 30 Aug 2015: Recruitment of leukocytes is a hallmark of stent thrombosis, according to results from the PRESTIGE study presented today at ESC Congress1 and published in European Heart Journal.2 The findings suggest that immune cell mediated thrombotic processes may be a realistic target for novel therapies to prevent stent thrombosis.
"Stent thrombosis (ST) is a life-threatening complication of percutaneous coronary intervention and recent large scale clinical registries reported an incidence of up to 0.4-0.6% per year," said principal investigator Professor ...
2015-08-31
How did the ankylosaur get its tail club? According to research from North Carolina State University and the North Carolina Museum of Natural Sciences that traces the evolution of the ankylosaur's distinctive tail, the handle arrived first on the scene, and the knot at the end of the tail followed.
The typical ankylosaur had a wide armored body and a flexible tail. But one group of ankylosaurs - ankylosaurids - also had a tail club that could have served as a useful weapon. These "weaponized" ankylosaurids lived about 66 million years ago, during the Cretaceous period. ...
2015-08-31
LONDON (Aug. 31, 2015) -- Cardiologists failed to identify more than half of basic and about 35 percent of advanced pre-recorded murmurs, but skills improved after a 90 minute training session, according to research presented today at the European Society of Cardiology Congress 2015.
Recent breakthroughs in the transcatheter treatment of aortic and mitral valve disorders provide new therapies for patients, but physicians must be able to detect valve problems in a timely manner for patients to see the full benefit of these advances, said Michael Barrett, MD, the lead ...
2015-08-31
London, UK - 31 Aug 2015: A gene associated with sudden cardiac death in the general population has been identified using implantable cardioverter defibrillator (ICD) monitoring in research presented for the first time at ESC Congress today.1 The research included patients from the DISCOVERY trial and Oregon-SUDS and discovered that a polymorphism in the GNAS gene predicted ventricular tachyarrhythmias and sudden cardiac death.
"This is the first time a gene has been identified using ICD monitoring and then confirmed to be associated with sudden cardiac death in the general ...
2015-08-31
LONDON, UK - 30 August, 2015: In patients with type 2 diabetes and acute coronary syndrome, the glucose-lowering medication lixisenatide did not increase or decrease the rate of cardiovascular (CV) events compared to placebo, according to results of the Evaluation of Lixisenatide in Acute Coronary Syndrome (ELIXA) trial.
The study, presented today at ESC Congress 2015, "demonstrates the cardiovascular safety of lixisenatide", reported Eldrin F. Lewis, MD, MPH, a member of the ELIXA trial's executive committee, a physician in the Cardiovascular Medicine Division at Brigham ...
2015-08-31
LONDON, UK - 30 August, 2015: Patients with type-2 diabetes and cardiovascular disease can safely take the antihyperglycemic drug sitagliptin without an increased risk of cardiovascular complications - even if they have a history of heart failure - a new analysis of the TECOS (Trial Evaluating Cardiovascular Outcomes with Sitagliptin) study shows.
The findings, presented today at ESC Congress 2015, "provide reassurance to patients and prescribers about the cardiovascular safety of sitagliptin" - a dipeptidyl peptidase-4 (DPP-4) inhibitor sitagliptin - according to Paul ...
2015-08-31
London, UK - 31 Aug 2015: Depressed patients have more frequent chest pain even in the absence of coronary artery disease, according to results from the Emory Cardiovascular Biobank presented at ESC Congress today by Dr Salim Hayek, a cardiologist at Emory University School of Medicine in Atlanta, Georgia, US.1 The findings suggest that pain and depression may share a common neurochemical pathway.
"Depression is a common and well recognised risk factor for the development of heart disease," said Dr Hayek. "Patients with known heart disease and depression tend to experience ...
2015-08-31
London, UK - 31 Aug 2015: Retrieval of larger thrombi during intra arterial treatment (IAT) is associated with improved neurological recovery after acute ischaemic stroke, according to a sub study of the MR CLEAN trial presented at ESC Congress today by Dr Anouchska Autar, PhD candidate at the Erasmus Medical Centre in Rotterdam, the Netherlands.1
"Acute ischaemic strokes occur when a blood clot, also called a thrombus, embolises to the brain where it restricts the flow of blood," said Dr Autar. "MR CLEAN was the first trial to show the benefit of IAT to remove blood ...
2015-08-31
India's bread basket, the Indo-Gangetic Plains (IGP), have been classified as a "hot spot" for air pollution. A recent study from the University of Eastern highlights the current status of ozone research in the IGP region, which is agriculturally important and densely populated.
To study adverse effects of ozone, field experiments were conducted with local crop cultivars of mustard (Brassica campestris L.) and rice (Oryza sativa L.), and various growth, physiological (gas-exchange), biochemical and yield parameters were studied throughout the growing season. Ethylenediurea ...
LAST 30 PRESS RELEASES:
[Press-News.org] NCI awards SPORE grant to multiple myeloma research team from Mayo Clinic Cancer Center