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Small labeling pair for single-molecule super-resolution imaging

2015-09-10

(Press-News.org) This news release is available in German.

Protein labeling with synthetic fluorescent probes is a key technology in chemical biology and biomedical research. The target proximity achieved by small-molecule probes is essential to exploit the full potential of super-resolution fluorescence microscopy. Single-molecule localization techniques provide high spatial resolution by reporting on the position of the fluorophore and thus only indirectly on the target molecule itself. Large labels, such as antibodies, can misleadingly position a fluorophore tens of nanometers away from the target. Since single-molecule localization microscopy can achieve almost the ultimate spatial precision ( END

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New species of human relative discovered

2015-09-10

An international research team, which includes NYU anthropologists Scott Williams and Myra Laird, has discovered a new species of a human relative. Homo naledi, uncovered in a cave outside of Johannesburg, South Africa, sheds light on the diversity of our genus and possibly its origin. "This discovery is unprecedented in the sheer number of hominins collected from such a small area in the virtual absence of other animal remains," says Williams, an assistant professor in NYU's Department of Anthropology. "That makes this site unique. Moreover, the announcement describes ...

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How genetic testing can improve care for children with epilepsy

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The steps involved in evaluating and diagnosing patients with epilepsy are complicated. In a new and extensive literature review of available information, experts provide insights on the valuable role of genetic testing in the diagnosis and care of pediatric epilepsy. Epilepsy is a common neurological disorder that affects up to 1.5% of the world's population and is more commonly diagnosed in children than adults. Most cases of epilepsy have been considered "idiopathic" or of unknown cause, but recent advances in genetic testing are providing insights on the potential ...

First new cache-coherence mechanism in 30 years

2015-09-10

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Fossil trove adds a new limb to human family tree

2015-09-10

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AGA recommends all patients with colorectal cancer get tested for Lynch syndrome

2015-09-10

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Cancer preventative surgery could become a thing of the past, new research suggests

2015-09-10

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New species of human relative discovered in S.A. cave

2015-09-10

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Small labeling pair for single-molecule super-resolution imaging

Less is more

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