Advanced materials in a snap

Australian research has identified a new mechanism in which prostate cancer cells can 'switch' character and become resistant to therapy. These findings, just published in Cell Reports, are an important development in unravelling how an aggressive subtype of prostate cancer, neuroendocrine prostate cancer (NEPC), develops after hormonal therapies. It is well established that some tumours show increased cellular 'plasticity' in response to new or stressful conditions, such as cancer therapy, says lead researcher Associate Professor Luke Selth, from the Flinders ...

What The Study Did: Data from public health surveillance of reported COVID-19 cases and seroprevalence surveys were used in this observational study that reports an estimated 46.9 million SARS-CoV-2 infections, 28.1 million symptomatic infections, 956,174 hospitalizations and 304,915 deaths occurred in the U.S. through November 15, 2020. Authors: Frederick J. Angulo, D.V.M., Ph.D., of  Medical Development and Scientific/Clinical Affairs of Pfizer Vaccines, is the corresponding author. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2020.33706) Editor's ...

A new study led by researchers at the Universities of Bristol, Exeter, and Bath helps to shed light on the winter weather we may soon have in store following a dramatic meteorological event currently unfolding high above the North Pole. Weather forecasting models are predicting with increasing confidence that a sudden stratospheric warming (SSW) event will take place today, 5 January 2021. The stratosphere is the layer of the atmosphere from around 10-50km above the earth's surface. SSW events are some of the most extreme of atmospheric phenomena and can see polar stratospheric temperature increase by up to 50°C over the course of a few days. Such events ...

By André Julião  |  Agência FAPESP - The black lion tamarin (Leontopithecus chrysopygus) once inhabited most forest areas in the state of São Paulo, Southeast Brazil, but currently occupies only some Atlantic Rainforest remnants there. In recent years, after various studies of the endangered species, environmental NGO Instituto de Pesquisas Ecológicas (IPÊ) moved groups of these animals to areas from which the species had disappeared.  Similar initiatives have now been reinforced by a group of researchers at IPÊ, São Paulo State University (UNESP) and the Federal University of Mato Grosso (UFMT), who cross-tabulated climate data and data on landscape (forest cover) to determine the sites best suited for future ...

The asteroid impact 66 million years ago that ushered in a mass extinction and ended the dinosaurs also killed off many of the plants that they relied on for food. Fossil leaf assemblages from Patagonia, Argentina, suggest that vegetation in South America suffered great losses but rebounded quickly, according to an international team of researchers. "Every mass extinction event is like a reset button, and what happens after that reset depends on which organisms survive and how they shape the biosphere," said Elena Stiles, a doctoral student at the University of Washington who completed the research as part of her master's thesis at Penn State. "All the biodiversity ...

PROVIDENCE, R.I. [Brown University] -- Last month, Japan's Hayabusa2 mission brought home a cache of rocks collected from a near-Earth asteroid called Ryugu. While analysis of those returned samples is just getting underway, researchers are using data from the spacecraft's other instruments to reveal new details about the asteroid's past. In a study published in Nature Astronomy, researchers offer an explanation for why Ryugu isn't quite as rich in water-bearing minerals as some other asteroids. The study suggests that the ancient parent body from which Ryugu was formed had likely dried out in some kind of heating event before Ryugu came into being, which left Ryugu itself drier than expected. "One of the ...

Repeated intravenous (IV) ketamine infusions significantly reduce symptom severity in individuals with chronic post-traumatic stress disorder (PTSD) and the improvement is rapid and maintained for several weeks afterwards, according to a study conducted by researchers from the Icahn School of Medicine at Mount Sinai. The study, published September XX in the American Journal of Psychiatry, is the first randomized, controlled trial of repeated ketamine administration for chronic PTSD and suggests this may be a promising treatment for PTSD patients. "Our findings provide insight into the treatment efficacy of repeated ketamine ...

As the world grows increasingly globalized, one of the ways that countries have come to rely on one another is through a more intricate and interconnected food supply chain. Food produced in one country is often consumed in another country -- with technological advances allowing food to be shipped between countries that are increasingly distant from one another. This interconnectedness has its benefits. For instance, if the United States imports food from multiple countries and one of those countries abruptly stops exporting food to the United States, there are still other countries that can be relied on ...

SAN ANTONIO and CHICAGO - An article published Jan. 5 in Alzheimer's & Dementia: The Journal of the Alzheimer's Association cites decades of published scientific evidence to make a compelling case for SARS-CoV-2's expected long-term effects on the brain and nervous system. Dementia researchers from The University of Texas Health Science Center at San Antonio (UT Health San Antonio) are the first and senior authors of the report and are joined by coauthors from the Alzheimer's Association and Nottingham and Leicester universities in England. "Since the flu pandemic of 1917 and 1918, many of the flulike diseases have been associated with brain disorders," said lead author ...

DURHAM, N.C. -- Self-control, the ability to contain one's own thoughts, feelings and behaviors, and to work toward goals with a plan, is one of the personality traits that makes a child ready for school. And, it turns out, ready for life as well. In a large study that has tracked a thousand people from birth through age 45 in New Zealand, researchers have determined that people who had higher levels of self-control as children were aging more slowly than their peers at age 45. Their bodies and brains were healthier and biologically younger. In interviews, the higher self-control group also showed they may be better equipped to handle the health, financial and social challenges of later life as well. The researchers used structured interviews and credit checks ...