PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Simulation helps refine pediatric care guidelines for COVID-19

Simulation helps refine pediatric care guidelines for COVID-19
2021-01-28
(Press-News.org) DALLAS - Jan. 28, 2021 - Simulation can be a viable way to quickly evaluate and refine new medical guidelines and educate hospital staff in new procedures, a recent study from UT Southwestern's Department of Pediatrics shows. The findings, published recently in the journal Pediatric Quality and Safety and originally shaped around new COVID-19-related pediatric resuscitation procedures at UTSW and Children's Health, could eventually be used to help implement other types of guidelines at medical centers nationwide.

For decades, U.S. hospitals have used the same standard procedures for CPR and intubation. But when the COVID-19 pandemic began early last year, some details of these procedures needed to change, explains Blake E. Nichols, M.D., assistant professor of pediatrics at UTSW and a critical care physician at Children's Health.

CPR and intubation are among procedures with the highest risk of spreading SARS-CoV-2, the virus that causes COVID-19, to health care workers. To help protect hospital staff, the American Heart Association (AHA) and the Society of Critical Care Medicine (SCCM) published recommendations in April 2020 for performing these procedures in the safest way possible on patients who are either positive for COVID-19 or suspected of having the virus.

Because children who are critically ill with COVID-19 make up just a fraction of the patient population, resuscitation is thankfully a rare event, says Nichols. But this rarity also makes it more difficult to create practical guidelines around these scenarios and educate hundreds of staff members who might be involved in these procedures at hospitals.

To evaluate best practices, Nichols and his colleagues performed a simulation using protocols that differ from the typical simulation events used for CPR or intubation training. The researchers started with new guidelines written by a UTSW/Children's Health committee based on AHA and SCCM recommendations. These guidelines had distinct differences from the usual resuscitation procedures, including involving a medical team with significantly fewer members, making sure each member is fully secured in personal protective equipment (PPE) before entering a patient's room, and ensuring the patient is enclosed in as much protective gear as possible to block the spray of infectious droplets.

Nichols pulled together a team of six individuals to participate in a resuscitation event. The team included pediatric intensive care physicians, nurses, respiratory therapists, and a writer from the guidelines committee.

The team tested the guidelines in two different scenarios: In one, a mock patient posed under a plastic equipment drape that had been repurposed as a protective shield, confirming its utility for protecting health care workers during intubation and CPR and determining how to secure the shield around the patient for best results. In another, the team performed simulated intubation and CPR on a mannequin in a negative pressure room, with some team members outside the room passing off equipment and medications and others actively treating the simulated patient.

During the four-hour event, the team used rapid cycle deliberate practice (RCDP), an established medical simulation technique that allows the exercise to be stopped at any time to refine guidelines or correct mistakes. But unlike typical RCDP - in which just one member acts as an expert and is in charge of stopping the simulation for corrections - in this case every member of the team was considered an expert, allowing each to give input, make quick changes, and hone the guidelines. The simulation was recorded to create an educational video for other hospital staff.

Nichols says the team identified several problems with the proposed guidelines written for UTSW/Children's Health. For example, the team found that two nurses were needed at the patient's bedside during resuscitation - rather than just one as proposed in the guidelines - to prevent task overload. Additionally, communication needed to be refined since the PPE prevented team members from clearly seeing facial expressions or hearing commands as they normally would.

The video was used to educate nearly 300 staff members at UTSW and Children's Health on the new guidelines within a few days, enabling a quick rollout, Nichols says. The entire procedure - from writing the guidelines to disseminating the video - took fewer than two weeks. He characterized that as an extremely fast turnaround necessitated by the pandemic.

"The COVID-19 pandemic required us to find new ways to provide the best care for our patients while protecting health care workers and educating these workers quickly on new procedures," Nichols says. "We've shown that simulation provides a great opportunity to accomplish this goal."

INFORMATION:

Other UTSW researchers who contributed to this study include Ali B.V. McMichael, A. Paige Davis Volk, Priya Bhaskar, and Cindy Darnell Bowens.


[Attachments] See images for this press release:
Simulation helps refine pediatric care guidelines for COVID-19

ELSE PRESS RELEASES FROM THIS DATE:

A glimpse into the wardrobe of King David and King Solomon, 3000 years ago

A glimpse into the wardrobe of King David and King Solomon, 3000 years ago
2021-01-28
"King Solomon made for himself the carriage; he made it of wood from Lebanon. Its posts he made of silver, its base of gold. Its seat was upholstered with purple, its interior inlaid with love." (Song of Songs 3:9-10) For the first time, rare evidence has been found of fabric dyed with royal purple dating from the time of King David and King Solomon. While examining the colored textiles from Timna Valley - an ancient copper production district in southern Israel - in a study that has lasted several years, the researchers were surprised to find remnants of woven fabric, a tassel and fibers of wool dyed with royal purple. Direct radiocarbon ...

Sotorasib provides durable clinical benefit for patients with NSCLC and KRAS mutations

2021-01-28
(For Immediate Release--Singapore--January 28, 2021)-- In the phase II CodeBreak 100 trial, sotorasib provided durable clinical benefit with a favorable safety profile in patients with pretreated non-small cell lung cancer (NSCLC) and who harbor KRAS p.G12C mutations, validating CodeBreak 100's phase I results, according to research presented today at the International Association for the Study of Lung Cancer World Conference on Lung Cancer. Outcome in patients with advanced NSCLC on second- or third-line therapies is poor, with a response rate of less than 20% and median progression-free survival of fewer than four months. Approximately 13% of patients with lung adenocarcinomas harbor KRAS p.G12C mutations. Sotorasib is a first-in-class small molecule that specifically ...

Researchers reveal in-situ manipulation of active Au-TiO2 interface

Researchers reveal in-situ manipulation of active Au-TiO<sub>2</sub> interface
2021-01-28
An international joint research team from the Shanghai Advanced Research Institute of the Chinese Academy of Sciences, along with Zhejiang University and the Technical University of Denmark, reported an in-situ strategy to manipulate interfacial structure with atomic precision during catalytic reactions. Results were published in the latest issue of Science. The interface between nanoparticles and substrates plays a critical role in heterogeneous catalysis because most active sites are located at the perimeter of the interface. It is generally believed that this interface is immobile and unchangeable, thus can hardly be adjusted in reactive environments. As a result, it has been challenging to promote catalytic activity through precise control of the interfacial ...

Viral sequencing can reveal how SARS-CoV-2 spreads and evolves

2021-01-28
The emergence of SARS-CoV-2 virus variants that are adding twists in the battle against COVID-19 highlight the need for better genomic monitoring of the virus, says Katia Koelle, associate professor of biology at Emory University. "Improved genomic surveillance of SARS-CoV-2 across states would really help us to better understand how the virus causing the pandemic is evolving and spreading in the United States," Koelle says. "More federal funding is needed, along with centralized standards for sample collection and genetic sequencing. Researchers need access to such metadata to better track how the virus is spreading geographically, and to identify any new variants ...

Screening asymptomatic health care personnel for COVID-19 not recommended by experts

2021-01-28
BOSTON -- Routine screening of asymptomatic health care personnel (HCP) in the absence of confirmed exposures to COVID-19 is not a recommended strategy for preventing transmission of the coronavirus causing the current global pandemic, according to a new review co-authored by an infectious disease specialist at Massachusetts General Hospital (MGH). The review, published in Infection Control & Hospital Epidemiology, found that such testing is unlikely to affect the transmission of SARS-CoV-2 in health care settings and could even have unintended negative consequences. Many universities, sports leagues and other institutions require individuals in their organization to undergo routine testing for COVID-19, whether or not they are experiencing symptoms. Current public ...

Marine heatwaves becoming more intense, more frequent

Marine heatwaves becoming more intense, more frequent
2021-01-28
When thick, the surface layer of the ocean acts as a buffer to extreme marine heating--but a new study from the University of Colorado Boulder shows this "mixed layer" is becoming shallower each year. The thinner it becomes, the easier it is to warm. The new work could explain recent extreme marine heatwaves, and point at a future of more frequent and destructive ocean warming events as global temperatures continue to climb. "Marine heatwaves will be more intense and happen more often in the future," said Dillon Amaya, a CIRES Visiting Fellow and lead author on the study out ...

Counties with more cannabis dispensaries show reduced opioid deaths

2021-01-28
Counties with a greater number of cannabis dispensary storefronts experience reduced numbers of opioid-related deaths relative to other locales, a recent University of California, Davis, study has found. This is the first study to examine the association between active cannabis dispensary operations -- both medical and recreational -- and opioid-related mortality rates at the county level, suggesting that providing alternative pain management could improve public health outcomes, researchers said. "While the associations documented cannot be assumed to be causal, they suggest a potential relationship between increased prevalence of medical and recreational cannabis dispensaries and reduced opioid-related ...

Mechanism for how pancreatic cancer evades immunotherapy elucidated

2021-01-28
WASHINGTON --- Pancreatic cancer, one of the most lethal of all cancers, is capable of evading attacks by immune cells by changing its microenvironment so that the immune cells suppress, rather than support, an attack on the tumor. The scientists also found that that some of the mediators of this suppressive response, including a protein called STAT1, represent potential therapeutic targets that could be used to reverse this evasion and point to possible treatment opportunities. The finding appears January 28, 2021, in Cancer Immunology Research. "This ...

New study unravels Darwin's 'abominable mystery' surrounding origin of flowering plants

2021-01-28
The origin of flowering plants famously puzzled Charles Darwin, who described their sudden appearance in the fossil record from relatively recent geological times as an "abominable mystery". This mystery has further deepened with an inexplicable discrepancy between the relatively recent fossil record and a much older time of origin of flowering plants estimated using genome data. Now a team of scientists from Switzerland, Sweden, the UK, and China may have solved the puzzle. Their results show flowering plants indeed originated in the Jurassic or earlier, that is millions of years earlier than their oldest undisputed fossil evidence, according to a new study published in the scientific journal Nature Ecology & Evolution. The lack of older ...

Loggerhead sea turtles lay eggs in multiple locations to improve reproductive success

2021-01-28
Although loggerhead sea turtles return to the same beach where they hatched to lay their eggs, a new study by a USF professor finds individual females lay numerous clutches of eggs in locations miles apart from each other to increase the chance that some of their offspring will survive. A study published in the journal "Scientific Reports" found that some females lay as many as six clutches as far as six miles apart during the same breeding season. "Nesting females don't lay all their eggs in one basket. Their reproductive strategy is like investing in a mutual fund. Females divide their resources among many stocks rather than investing everything in a single stock," said Deby Cassill, biology professor ...

LAST 30 PRESS RELEASES:

Genetic discovery links new gene to autism spectrum disorder

Chemistry: Algorithm can sniff out whisky’s strongest notes and origin

Researchers develop personalized stem cell model ALS for fast, individualized drug testing

Evolutionary study reveals the toxic reach of disease-causing bacteria across the Plant Kingdom

Cold-related deaths in the US

Brief outpatient rehabilitation program for post–COVID-19 condition

Racial and ethnic differences in outcomes of neonates born at less than 30 weeks’ gestation

Physical activity during pregnancy and preterm birth among women with gestational diabetes

Developmental disorder discovery could lead to better treatments for Rett syndrome

Laser-based artificial neuron mimics nerve cell functions at lightning speed

Empowering young scientists to build a sustainable future

New review explores advances in alcohol-associated liver disease

Reducing dose of popular blood thinners may limit risk of future bleeding

How to deal with narcissists at home and at work

First-of-its-kind study uses remote sensing to monitor plastic debris in rivers and lakes

This prototype sunscreen protects your skin and cools you off, too

Access to vaccines and clinical trials for pregnant women vital in pandemics

Effect of somatosensory electrical stimulation on hand choice

The surprising role of gut infection in Alzheimer’s disease

Allen Institute announces 2024 Next Generation Leaders

Graz University of Technology develops modular timber high-rise building for resource-efficient construction

Research alert: New software unlocks secrets of cell signaling

A user manual for yeast’s genetic switches

More people living without running water in US cities since the global financial crisis

Study finds slowing of age-related declines in older adults

Tinkering with the “clockwork” mechanisms of life

Machine psychology – a bridge to general AI

Walking speed as a simple predictor of metabolic health in obese individuals

Houston Methodist scientists make surprising discovery pinpointing when good cholesterol becomes harmful

Shiitake-derived functional food shows suppression of liver fibrosis progression

[Press-News.org] Simulation helps refine pediatric care guidelines for COVID-19