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Semaglutide paired with intensive behavioral therapy showed triple weight loss vs placebo

In study at Penn Medicine and other locations, participants lost an average of 16% of starting weight, more than one-third lost 20% or more of baseline weight

2021-02-24
(Press-News.org) PHILADELPHIA -- A second study of the injectable anti-obesity medication, semaglutide, has confirmed the large weight losses reported in a study earlier this month, establishing the reliability and robustness of this new drug. With obesity affecting more than 40 percent of American adults, the findings could have a major impact on weight management in primary care and other settings. The END


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Scientists begin building highly accurate digital twin of our planet

2021-02-24
To become climate neutral by 2050, the European Union launched two ambitious programmes: "Green Deal" and "DigitalStrategy". As a key component of their successful implementation, climate scientists and computer scientists launched the "Destination Earth" initiative, which will start in mid-?2021 and is expected to run for up to ten years. During this period, a highly accurate digital model of the Earth is to be created, a digital twin of the Earth, to map climate development and extreme events as accurately as possible in space and time. Observational data will be continuously incorporated into the digital ...

SwRI scientist captures evidence of dynamic seasonal activity on a Martian sand dune

SwRI scientist captures evidence of dynamic seasonal activity on a Martian sand dune
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SAN ANTONIO -- Feb. 24, 2021 -- A Southwest Research Institute® (SwRI®) scientist examined 11 Mars years of image data to understand the seasonal processes that create linear gullies on the slopes of the megadune in the Russell crater on Mars. In early spring images, captured by two different cameras on the Mars Reconnaissance Orbiter, SwRI's Dr. Cynthia Dinwiddie noticed airborne plumes of dusty material associated with the linear dune gullies on the sand dune's downwind slope. These clues point to active processes involving chunks of frozen CO2, or dry ice, sliding down the sand dune, kicking up sand and dust along the way. Russell crater, on Mars, ...

Cellular seafood

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Meat alternatives are officially mainstream. To wit, Burger King added the plant-based Impossible Burger to its menu nationwide in 2019, and McDonald's plans to unveil its own McPlant in 2021. Alongside these vegetarian options, many companies are also working to culture meat outside of animals grown from cell lines. Proponents highlight a range of potential environmental and health benefits offered by this emerging industry, and several companies believe that these benefits could also play out with seafood. A multidisciplinary team of researchers has taken a good, hard look at what it would take for cell-based seafood to deliver conservation benefits. They have ...

Discovery offers potential for stripping tumors of T cell protection

Discovery offers potential for stripping tumors of T cell protection
2021-02-24
Immunologists at St. Jude Children's Research Hospital have discovered that tumors use a unique mechanism to switch on regulatory T cells to protect themselves from attack by the immune system. Surprisingly, the mechanism does not affect regulatory T cell function outside the tumor and may therefore limit the immune-associated toxicities of targeting regulatory T cells. The finding offers the promise of drug treatment to selectively shut down regulatory T cells in a tumor, rendering the tumor vulnerable to cancer immunotherapies that activate the immune ...

The GovLab at NYU Tandon releases report on the impact of online communities

2021-02-24
BROOKLYN, New York, Wednesday, February 24, 2021 -The Governance Lab (The GovLab) at the NYU Tandon School of Engineering released a report, "The Power of Virtual Communities," which examines the role online groups play in creating opportunities for people to build new kinds of meaningful communities they often could not form in real space. This first-of-its-kind research was built on interviews with 50 Facebook community leaders in 17 countries, 26 global experts from academia and industry, unique access to Facebook's underlying research and an original global survey conducted by YouGov of 15,000 people in 15 countries who are currently members of online and ...

Reducing salt in Parmigiano Reggiano cheese might not negatively affect its flavor

2021-02-24
Aged cheeses pack a punch of nutty, sharp flavor. Before they're fully mature, aged cheeses are either waxed or placed in brine for weeks to create a natural rind. However, the high salt content in brined cheeses deters some consumers. Now, researchers reporting in ACS Food Science & Technology present a shortened brining time for Parmigiano Reggiano that results in a less salty product, while still potentially maintaining the cheese's distinctive texture and flavor compounds. Parmigiano Reggiano is a lactose-free, crumbly and hard cheese. Manufactured ...

Research shows how single celled algae rotate as they swim towards the light

2021-02-24
Scientists have made a pivotal breakthrough in the quest to understand how single-cell green algae are able to keep track of the light as they swim. A team of researchers from the University of Exeter's flagship Living Systems Institute has discovered how the model alga Chlamydomonas is seemingly able to scan the environment by constantly spinning around its own body axis in a corkscrewing movement. This helps it respond to light, which it needs for photosynthesis. The tiny alga, which is found abundantly in fresh-water ponds across the world, swims by beating its two flagella, hair-like structures that adopt a whip-like movement to move the cell. These flagella beat in much the same way as the cilia in the human respiratory ...

Most women receive inappropriate treatment for urinary tract infections

2021-02-24
NEW YORK (February 24, 2021) -- Nearly half of women with uncomplicated urinary tract infections received the wrong antibiotics and almost three-quarters received prescriptions for longer than necessary, with inappropriately long treatment durations more common in rural areas, according to a study of private insurance claims data published today in Infection Control & Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America. "Inappropriate antibiotic prescriptions for uncomplicated urinary tract infections are prevalent and come with serious patient- and society-level consequences," said Anne Mobley Butler, PhD, lead author of the study and assistant professor ...

From melody to language

2021-02-24
In the first few months of their lives, babies cry, babble, gurgle and make a variety of other peculiar sounds. It can be difficult to imagine that they are actually laying the foundations for later speech with these utterances. However, there is a determining element that proves that even their cries can be assigned to a particular language: the speech melody - or, more accurately: prosody. "Every language is characterised by specific musical elements, which we call prosody," says Kathleen Wermke. Prosody, in simple terms, is the combination of intonation (melody) and rhythm. Earlier studies have shown that even newborns are able to distinguish different languages, like German ...

Research addresses the complex problems of malaria

Research addresses the complex problems of malaria
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Everyone knows 2 + 2 = 4, but what about mosquitoes plus malaria? Lauren Childs, an assistant professor in the Department of Mathematics at Virginia Tech, says there's an equation for that too. Childs recently co-authored a report with a team from Harvard University on the role of natural mosquito behavior on transmission of a disease that threatens half the world's population. The study, "Multiple blood feeding in mosquitoes shortens the Plasmodium falciparum incubation period and increases malaria transmission potential," was published in the December 2020 issue of PLOS Pathogens. "Worldwide there are about 400,000 deaths and 200 million cases each year from malaria," said Childs, a faculty member with the Virginia Tech College ...

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[Press-News.org] Semaglutide paired with intensive behavioral therapy showed triple weight loss vs placebo
In study at Penn Medicine and other locations, participants lost an average of 16% of starting weight, more than one-third lost 20% or more of baseline weight