(Press-News.org) The Wellcome Trust, one of the world's top funders of health research, stands to gain financially from the covid-19 pandemic, raising questions about transparency and accountability, reports The BMJ today.
Independent journalist Tim Schwab shows how the charity plays a leading role in a WHO programme to support new covid-19 therapeutics, while holding investments in companies producing these same treatments.
It follows news reports that another charity, the Gates Foundation, is also positioned to potentially benefit financially from its leading role in the pandemic response.
Financial disclosures from late 2020 show that Wellcome has a £275m stake in Novartis, which manufactures dexamethasone, and a £252m stake in Roche, which is helping to manufacture monoclonal antibodies with Regeneron.
Wellcome's financial interests have been published on the trust's website and through financial regulatory filings, explains Schwab, but do not seem to have been disclosed as financial conflicts of interest in the context of Wellcome's work on covid-19.
The Wellcome Trust disputes that its investments compromise - or conflict with - its independence, and say they "would never make decisions or advise others about the pandemic response for a reason other than public health."
Wellcome's supporters describe the deep well of biomedical expertise the charity brings to the pandemic, while Unitaid, which co-leads the WHO project, says that it has a "clear mutual understanding" with Wellcome "that relevant institutional interests will be transparently disclosed."
Marc Rodwin, professor of law at Suffolk University in Boston, Massachusetts, says that institutions with financial conflicts of interest can still make valuable contributions to the pandemic response but should not be in a position of influence or decision making.
But Mohga Kamal-Yanni, a policy adviser to UNAIDS and other organisations says it's important to know that decisions are being made based on evidence and science. And Unitaid told The BMJ last December, "We have not received any declaration of conflict of interest."
Schwab notes that, in addition to its work through WHO, Wellcome also influences the pandemic response through its director, Jeremy Farrar's position on the Scientific Advisory Group for Emergencies advising the UK government on covid-19, as well as his board seat on the Coalition for Epidemic Preparedness Innovations, a leading public-private partnership in the pandemic that has pledged more than $1bn to covid-19 vaccine development.
He also features frequently as an expert in the news media, including The BMJ, where he has cited the potential of specific drugs against covid-19.
Wellcome would not comment on the desirability of Farrar's dual roles - helping manage the trust's money and its charitable mission - and refused to disclose the full details of its investment portfolio to The BMJ. But Schwab points out that Wellcome reports gains of £3.3bn from all investments in 2020, three times more money than the trust gave away in charity.
"Despite the outsize role that private charities play in the pandemic response, their financial interests have been little scrutinised, likely because foundations are not subject to the same oversight mechanisms as public institutions," says Schwab.
But Linsey McGoey, a professor of sociology at the University of Essex, who has written extensively on accountability in philanthropy, views Wellcome's and Gates's pharma investments in the context of their support for the prevailing market mechanisms driving modern medicine - which has translated into wealthy nations getting priority access to covid-19 drugs.
"These foundations sort of perpetuate the false ideological impression that they are ... solving the problem even when they're not. And they might be compounding it by perpetuating this ideological impression of private sector saviourism," she notes.
INFORMATION:
Externally peer reviewed? No
Evidence type: Investigation
Subject: The Wellcome Trust
More than three quarters (78%) of hospitals surveyed between June and August 2020 reported that their paediatric cancer care had been affected by the pandemic.
Almost half (43%) made fewer new cancer diagnoses than expected, while around one third (34%) noted a rise in the number of patients abandoning treatment.
Nearly one in ten (7%) closed their paediatric cancer units completely at some stage during the pandemic.
Hospitals in low- and middle-income countries (LMICs) were disproportionately affected, with unavailability of chemotherapy, treatment abandonment, and disrupted radiotherapy among issues more frequently reported.
The COVID-19 pandemic has had major impacts on childhood cancer care worldwide, ...
Daily infusions of albumin provide no significant health benefit to patients hospitalised with advanced liver disease, over and above 'standard care', finds a large-scale multicentre trial led by UCL researchers.
Albumin is a protein made in the liver that prevents fluid leaking from the bloodstream to other body tissues and carries various substances throughout the body, such as hormones or enzymes. In people with liver disease, low albumin levels are associated with an increased risk of death among hospitalised patients who have cirrhosis, and laboratory studies have shown albumin to have an anti-inflammatory effect. Therefore, albumin infusions are considered the best fluid for patients with cirrhosis and are an integral part of clinical care.
Explaining the ATTIRE* trial, Principal ...
BOSTON - As the speed and scale of vaccinations against the SARS-CoV-2 virus ramps up globally, researchers at Massachusetts General Hospital (MGH) are calling for greater awareness and communication around a delayed injection-site reaction that can occur in some patients who have received the Moderna mRNA-1273 vaccine.
In a letter to the editor published online in The New England Journal of Medicine (NEJM), the authors note Phase 3 clinical data from the Moderna vaccine trial did show delayed skin hypersensitivity in a small number of the more than 30,000 trial participants. However, the authors say the large, red, sometimes raised, itchy or painful skin reactions were never fully characterized ...
Scientists say outdated assumptions around gender continue to hinder effective and fair policymaking and action for climate mitigation and adaptation.
Lead author of a new study, Dr Jacqueline Lau from the ARC Centre of Excellence for Coral Reef Studies at James Cook University (Coral CoE at JCU) and WorldFish, said gender--alongside other identities like race, class and age--has a powerful influence on people's experience of, and resilience to, climate change.
She said the four most common and interlinked assumptions found are: women are innately caring and connected to the environment; women are a homogenous and vulnerable group; gender equality is a women's issue and; gender equality ...
ITHACA, N.Y. - How might people's political ideology affect their perception of race?
Previous research by Amy Krosch, assistant professor of psychology in the College of Arts and Sciences, has shown that white people who identify themselves as political conservatives tend to have a lower threshold for seeing mixed-race Black and white faces as Black.
More often than liberals, Krosch found, white political conservatives show a form of social discrimination termed "hypodescent" - categorizing multiracial individuals as members of the "socially subordinate" racial group.
In new research published Feb. 22 in Philosophical Transactions of Royal Society B, Krosch used neuroimaging to show that this effect seems to be driven by white ...
As COVID-19 lockdowns and quarantines are lifted, businesses are now faced with the challenge of how to keep their employees who are returning to work motivated and engaged.
A study led by a University of Illinois Chicago researcher shows that both employees and managers have an important part to play in promoting employee engagement during the pandemic.
The research, published in the Journal of Applied Psychology, suggests employee engagement and performance are the highest when employees are mentally prepared for their return to work and their managers are strongly committed to employees' health and safety at work.
"Given the turmoil and distress during lockdowns ...
To investigate humans' impact on freshwater resources, scientists have now conducted the first global accounting of fluctuating water levels in Earth's lakes and reservoirs - including ones previously too small to measure from space.
The research, published March 3 in the journal Nature, relied on NASA's Ice, Cloud and land Elevation Satellite 2 (ICESat-2), launched in September 2018.
ICESat-2 sends 10,000 laser light pulses every second down to Earth. When reflected back to the satellite, those pulses deliver high-precision surface height measurements every 28 inches (70 centimeters) along the satellite's orbit. With these trillions of data points, scientists can distinguish more features of Earth's surface, like small lakes and ponds, and track them over ...
Climate change is generally portrayed as an environmental and societal threat with entirely negative consequences. However, some sectors of the global economy may actually end up benefiting.
New economic and philosophical research argues that policymakers must consider both the beneficial effects of climate change to "climate winners" as well as its costs in order to appropriately incentivize actions that are best for society and for the environment.
The study by researchers from Princeton University, University College Cork, and HEC Montréal appears to be the first to develop a systematic, ethical framework for addressing climate winners -- as well as those harmed -- using financial transfers.
Their approach, called "Polluter Pays, Then Receives," requires ...
A recent survey of the approximately 274,000 City University of New York (CUNY) students published in the Journal of Urban Health found that the Covid-19 pandemic has taken a toll on their mental health and financial security.
The population-representative survey, conducted by a team of CUNY SPH faculty in collaboration with researchers at Healthy CUNY, found that more than half of CUNY students (54%) reported experiencing depression and/or anxiety in April 2020, at the height of the first wave of the Covid-19 pandemic. Further, they found disturbingly high levels of financial instability and noted that food insecurity and housing worries were strong ...
Injecting hydrogels containing stem cell or exosome therapeutics directly into the pericardial cavity could be a less invasive, less costly, and more effective means of treating cardiac injury, according to new research from North Carolina State University and the University of North Carolina at Chapel Hill.
Stem cell therapy holds promise as a way to treat cardiac injury, but delivering the therapy directly to the site of the injury and keeping it in place long enough to be effective are ongoing challenges. Even cardiac patches, which can be positioned directly over the site of the injury, have drawbacks in that they require invasive surgical ...