(Press-News.org) Toronto, ON -A new study published in the journal Substance Use and Misuse has found that adverse childhood experiences, such as physical and sexual abuse and neglect, predict greater performance-enhancing substance use in young adults.
Analyzing a sample of over 14,000 U.S. young adults from the National Longitudinal Study of Adolescent to Adult Health, researchers found that adverse childhood experiences are strongly associated with both legal (e.g., creatine monohydrate) and illegal (e.g., anabolic-androgenic steroids) performance-enhancing substance use. This relationship was especially strong among individuals who experienced sexual abuse during childhood, where the likelihood of using anabolic-androgenic steroids increased nine times among men and six times among women.
"Performance-enhancing substance use is common among young adults, despite many adverse outcomes associated with their use, such as the development of eating disorders, muscle dysmorphia, and substance use disorders. To date, we've known relatively little about what may lead to the use of these substances," says lead author Kyle T. Ganson, PhD, MSW, assistant professor at the University of Toronto's Factor-Inwentash Faculty of Social Work. "While it's been documented that adverse childhood experiences are associated with mental health conditions and other substance use behaviors, this study expands our knowledge by now including performance-enhancing substance use."
Over 25% of both men and women in the study reported physical abuse, while roughly 4% reported sexual abuse in childhood. Over 15% of men reported legal performance-enhancing substance use, while 3% reported anabolic-androgenic steroid use. Among both men and women in the study, experiencing all four of the adverse childhood experiences studied had the strongest effect on use of performance-enhancing substance use.
"Our results continue to confirm that experiencing a greater, cumulative number of adverse childhood experiences is strongly associated with poor outcomes. This was particularly true in our study, as both men and women who reported four adverse childhood experiences were significantly more likely to report performance-enhancing substance use," says Ganson.
Being the first known study to investigate such associations between adverse childhood experiences and performance-enhancing substance use, this article's conclusions add to the growing understanding of risk factors of performance-enhancing substance use, as well as add to the literature on the effects of childhood trauma.
"Experiencing childhood abuse may lead to a desire to develop a large, muscular body to protect against future interpersonal trauma, and young people commonly use performance-enhancing substances to build muscle.," says senior author Jason M. Nagata, MD, MSc, assistant professor at the University of California, San Francisco's Department of Pediatrics. "In addition to other adverse health outcomes, legal performance-enhancing substance use has been linked to anabolic steroid use, which can lead to irritability, aggression, poor mental health, heart disease, and liver damage."
This study provides further insight into the importance of monitoring for potential performance-enhancing substance use among patients with reported adverse childhood experiences, in addition to providing psychoeducation regarding the consequences associated with performance-enhancing substance use.
"Medical and mental health professionals should be aware of the common use of performance-enhancing substances, particularly among boys and men. Screening for performance-enhancing substance use and adverse childhood experiences should be a regular occurrence," says Ganson. "We also need to ensure that current public policy is informed by research to protect the health and well-being of adolescents and young adults from the adverse outcomes associated with adverse childhood experiences and the dangers of performance-enhancing substance use."
INFORMATION:
(March 17, 2021) -- Eric Shattuck, assistant professor of research in the UTSA Institute for Health Disparities Research (IHDR) at The University of Texas at San Antonio, is studying the phenomenon of social distancing in response to infectious disease and its effects on pathogen transmission and the health of individuals and communities.
Many animals, including humans, exhibit behavioral changes during the early stages of an infection, including reduced social contacts, called sickness behavior. His findings suggest innate social distancing might help prevent the infection ...
Gun violence in popular prime-time broadcast television dramas has increased steadily over almost two decades, a trend that parallels the rise in U.S. homicide deaths attributable to firearms, according to research by the Annenberg Public Policy Center (APPC) of the University of Pennsylvania.
Overall gun violence on popular prime-time dramas doubled from 2000 through 2018, according to the study, which was published in PLOS ONE. More important, gun violence as a proportion of the violence depicted in the shows rose significantly as well.
"Our research found that gun use substantially increased from 2000 to 2018 on prime-time ...
A study led by researchers at the University of California San Diego Jacobs School of Engineering provides new insights for developing therapies for muscle disease, injury and atrophy. By studying how different pluripotent stem cell lines build muscle, researchers have for the first time discovered how epigenetic mechanisms can be triggered to accelerate muscle cell growth at different stages of stem cell differentiation.
The findings were published Mar. 17 in Science Advances.
"Stem cell-based approaches that have the potential to aid muscle regeneration and growth would improve the quality of life for many people, from children ...
ROCHESTER, Minn. -- Pharmacogenomics is a valuable tool for health care providers to help prescribe the right drug for the right patient to enhance efficacy and avoid side effects.
A new research paper funded in part by the National Heart, Lung and Blood Institute (NHLBI) shows a clear advantage of genetic testing in helping health care providers choose the appropriate anti-platelet drug. Testing helps determine if a patient carries genetic variants in CYP2C19 that cause loss of its function. These variants interfere with the body's ability to metabolize and activate clopidogrel, an anti-platelet medication.
Anti-platelet drugs are given to prevent complications from blood clotting after a procedure to open clogged arteries. These patients can use one of ...
While scientists have known that creatures may adjust the timing of their daily routines based on starvation and predation, these shifts have only previously been measured based on data from a population at a single point in time. Now, using data collected as 71 elephant seals undertook their foraging migrations across the North Pacific Ocean, researchers report a view of how these animals divide their time between light and darkness to optimize tradeoffs between risks and rewards based on 7 months of data per seal, collected between 2004 and 2012. Their findings refute a hypothesis about how seals prioritize feeding. To better understand how seals divide their time between light ...
The giraffe is a truly puzzling animal. With its exceptional anatomy and suite of evolutionary adaptations, the giraffe is an outstanding case of animal evolution and physiology. Now, an international team of researchers from the University of Copenhagen and Northwestern Polytechnical University in China have produced a high-quality genome from the giraffe and investigated which genes are likely to be responsible for its unique biological features.
The extraordinary stature of the giraffe has led to a long list of physiological co-adaptations. The blood pressure of the giraffe, for instance, is twice as high as in humans and ...
Washington, DC-- Algae colonizing dead coral are upending scientists' ability to accurately assess the health of a coral reef community, according to new work from a team of marine science experts led by Carnegie's Manoela Romanó de Orte and Ken Caldeira. Their findings are published in Limnology and Oceanography.
Corals are marine invertebrates that build tiny exoskeletons, which accumulate to form giant coral reefs. Widely appreciated for their beauty, these reefs are havens for biodiversity and crucial for the economies of many coastal communities. But they are endangered by ocean warming, seawater ...
Information on individuals' mobility--where they go as measured by their smartphones--has been used widely in devising and evaluating ways to respond to COVID-19, including how to target public health resources. Yet little attention has been paid to how reliable these data are and what sorts of demographic bias they possess. A new study tested the reliability and bias of widely used mobility data, finding that older and non-White voters are less likely to be captured by these data. Allocating public health resources based on such information could cause disproportionate harms to high-risk elderly and minority groups.
The study, by researchers at Carnegie Mellon University (CMU) and Stanford University, appears in the Proceedings of the ...
Oncotarget published "Genomic and neoantigen evolution from primary tumor to first metastases in head and neck squamous cell carcinoma" which reported that prior work has characterized changes in the mutation burden between primary and recurrent tumors; however, little work has characterized the changes in neoantigen evolution.
These authors characterized genomic and neoantigen changes between 23 paired primary and recurrent head and neck squamous cell carcinoma (HNSCC) tumors.
Within these tumors, they identified 6 genes which have predicted neoantigens in 4 or more patients.
Within HNSCC tumors examined in this Oncotarget ...
A sustainable, powerful micro-supercapacitor may be on the horizon, thanks to an international collaboration of researchers from Penn State and the University of Electronic Science and Technology of China. Until now, the high-capacity, fast-charging energy storage devices have been limited by the composition of their electrodes -- the connections responsible for managing the flow of electrons during charging and dispensing energy. Now, researchers have developed a better material to improve connectivity while maintaining recyclability and low cost. ...