PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

New research finds delaying surgical procedures increases infection risk and health care costs

Study in the Journal of the American College of Surgeons makes the case for performing more procedures on day of admission

2010-12-16
(Press-News.org) CHICAGO (December 15, 2010) – Delaying elective surgical procedures after a patient has been admitted to the hospital significantly increases the risk of infectious complications and raises hospital costs, according to the results of a new study in the December issue of the Journal of the American College of Surgeons.

The occurrence of infection following surgical procedures continues to be a major source of morbidity and expense despite extensive prevention efforts that have been implemented through educational programs, clinical guidelines, and hospital-based policies. The authors of the study queried a nationwide sample of 163,006 patients, 40 years of age and older, from 2003 to 2007. They evaluated patients who developed postoperative complications following one of three high-volume elective surgical procedures: 87,318 coronary artery bypass graft (CABG) procedures, 46,728 colon resections, and 28,960 lung resections.

The infectious complications evaluated included pneumonia, urinary tract infections, postoperative sepsis and surgical site infections. Researchers found that for each type of procedure, infection rates increased significantly from those performed on the day of admission to those performed one, two to five, and six to 10 days later. Total infection rates after CABG increased from 5.7 percent on the day of admission to 18.2 percent at six to 10 days. Similar increases were noted after colon resection (from 8.4 to 21.6 percent) and after lung resection (from 10.2 to 20.6 percent; p < 0.0001 for all trends). The delays significantly inflated total hospital costs. Mean cost significantly increased with delays for all procedures evaluated: CABG: $36,079 to $47,527; colon resections: $20,265 to $29,887; and lung resections: $26,323 to $30,571.

"Multiple factors can contribute to postsurgical complications, including age and coexisting health issues," said lead study author Todd R. Vogel, MD, MPH, FACS, assistant professor of surgery at the University of Medicine & Dentistry of New Jersey, Robert Wood Johnson Medical School, New Brunswick. "This analysis, however, confirms a direct correlation between delaying procedures and negative patient outcomes. As pay-for-performance models become increasingly prevalent, it will be imperative for hospitals to consider policies aimed at preventing delays and thereby reducing infection rates."

Factors associated with in-hospital procedure delays included advanced age (80 years and older), female gender, minority status, and existing health issues including congestive heart failure, chronic pulmonary disease, and renal failure. Postoperative complications most associated with delay in CABG and colon resection were urinary tract infections and pneumonia, while delayed lung resections increased rates of sepsis and pneumonia. Mortality was significantly greater when CABG procedures and lung resections were postponed more than five days.

The study analyzed data collected from the Healthcare Cost and Utilization Project (HCUP) Nationwide Inpatient Sample (NIS), the largest publicly available all-payer inpatient care database in the U.S. and was sponsored by the Agency for Healthcare Research and Quality (AHRQ). The database includes all inpatient stay records from approximately 20 percent of U.S. community short-stay hospitals.

INFORMATION: About the American College of Surgeons

The American College of Surgeons is a scientific and educational organization of surgeons that was founded in 1913 to raise the standards of surgical practice and to improve the care of the surgical patient. The College is dedicated to the ethical and competent practice of surgery. Its achievements have significantly influenced the course of scientific surgery in America and have established it as an important advocate for all surgical patients. The College has more than 77,000 members and is the largest organization of surgeons in the world. For more information, visit www.facs.org.



ELSE PRESS RELEASES FROM THIS DATE:

Opportunity leads to promiscuity among squirrels, study finds

Opportunity leads to promiscuity among squirrels, study finds
2010-12-16
University of Guelph researchers have finally figured out why female squirrels are so darn promiscuous. Turns out it has nothing to do with genes and everything to do with how many males are knocking at their door. "Their behaviour is overwhelmingly influenced by opportunity," said graduate student Eryn McFarlane, who, along with integrative biology professor Andrew McAdam and a team of researchers from across Canada, solved a mystery that has baffled biologists for years. Their findings appear in the Royal Society Journal Biology Letters. Female squirrels are less ...

'Green genes' in yeast may boost biofuel production by increasing stress tolerance

2010-12-16
An effort to increase biofuel production has led scientists to discover genes in yeast that improve their tolerance to ethanol, allowing them to produce more ethanol from the same amount of nutrients. This study, published in the December 2010 issue of Genetics (http://www.genetics.org), shows how genetically altered yeast cells survive higher ethanol concentrations, addressing a bottleneck in the production of ethanol from cellulosic material (nonfood plant sources) in quantities that could make it economically competitive with fossil fuels. "Our hope is that this ...

Ancient forest emerges mummified from the Arctic

Ancient forest emerges mummified from the Arctic
2010-12-16
SAN FRANCISCO -- The northernmost mummified forest ever found in Canada is revealing how plants struggled to endure a long-ago global cooling. Researchers believe the trees -- buried by a landslide and exquisitely preserved 2 to 8 million years ago -- will help them predict how today's Arctic will respond to global warming. They also suspect that many more mummified forests could emerge across North America as Arctic ice continues to melt. As the wood is exposed and begins to rot, it could release significant amounts of methane and carbon dioxide into the atmosphere ...

New colonoscopy skills assessment tool developed for trainees

2010-12-16
OAK BROOK, Ill. – Dec. 15, 2010 – Researchers at the Mayo Clinic in Rochester, Minn., have developed a new skills assessment tool for colonoscopy trainees. A report outlining the development and validation of the Mayo Colonoscopy Skills Assessment Tool (MCSAT), designed for the assessment of cognitive and motor skills during colonoscopy training, appears in the December issue of GIE: Gastrointestinal Endoscopy, the monthly peer-reviewed scientific journal of the American Society for Gastrointestinal Endoscopy (ASGE). Ensuring that gastroenterology fellows and surgery ...

Missing molecules hold promise of therapy for pancreatic cancer

2010-12-16
By determining what goes missing in human cells when the gene that is most commonly mutated in pancreatic cancer gets turned on, Johns Hopkins scientists have discovered a potential strategy for therapy. The production of a particular cluster of genetic snippets known as microRNAs is dramatically reduced in human pancreatic tumor cells compared to healthy tissue, the researchers report in a study published Dec. 15 in Genes and Development. When the team restored this tiny regulator, called miR-143/145, back to normal levels in human pancreatic cancer cells, those cells ...

Nanoscale gene 'ignition switch' may help spot and treat cancer

2010-12-16
In a proof of principal study in mice, scientists at Johns Hopkins and the Virginia Commonwealth University (VCU) have shown that a set of genetic instructions encased in a nanoparticle can be used as an "ignition switch" to rev up gene activity that aids cancer detection and treatment. The switch, called a promoter, is a set of chemical letters that interacts with DNA to turn on gene activity. In this case, the scientists used a promoter called PEG-Prom, cloned by VCU researcher Paul Fisher, Ph.D. PEG-Prom is activated only when inside cancer cells, not in normal ones. "With ...

UGA researchers develop rapid diagnostic test for common type of pneumonia

2010-12-16
Athens, Ga. – University of Georgia researchers have developed a technique that can diagnose a common type of pneumonia within minutes, potentially replacing existing tests that can take several days for results. The researchers, whose findings are detailed online in the journal PLoS ONE, detected Mycoplasma pneumoniae, which causes atypical or "walking pneumonia," in true clinical samples with over 97 percent accuracy using a recently-developed nanotechnology-based platform. "If you can make a positive identification from a 10-minute test, then appropriate antibiotics ...

A positive mood allows your brain to think more creatively

2010-12-16
People who watch funny videos on the internet at work aren't necessarily wasting time. They may be taking advantage of the latest psychological science—putting themselves in a good mood so they can think more creatively. "Generally, positive mood has been found to enhance creative problem solving and flexible yet careful thinking," says Ruby Nadler, a graduate student at the University of Western Ontario. She and colleagues Rahel Rabi and John Paul Minda carried out a new study published in Psychological Science, a journal of the Association for Psychological Science. ...

Protein disables p53, drives breast cells toward cancer transition

Protein disables p53, drives breast cells toward cancer transition
2010-12-16
HOUSTON - The recently identified TRIM24 protein plays an active role in pushing normal breast cells into rapid cell proliferation and, potentially, into breast cancer. Reporting in the journal Nature, a team led by researchers at The University of Texas MD Anderson Cancer Center found that TRIM24 (tripartite motif-containing 24) pushes estrogen-responsive genes toward active expression. This expression, in turn, sets the stage for malignant transformation of breast cells. TRIM24 functions by reading a specific code, or signature, present at estrogen-regulated genes and ...

Elevated zinc concentrations in Colorado waterway likely a result of climate change

Elevated zinc concentrations in Colorado waterway likely a result of climate change
2010-12-16
Rising concentrations of zinc in a waterway on Colorado's Western Slope may be the result of climate change that is affecting the timing of annual snowmelt, says a new study led by the University of Colorado at Boulder. The study focused on the Snake River watershed just west of the Continental Divide near Keystone, Colo., where CU-Boulder researchers have observed a four-fold increase in dissolved zinc over the last 30 years during the lowest water flow months, said Caitlin Crouch. Crouch, a master's degree student who led the study, said the high levels of zinc affect ...

LAST 30 PRESS RELEASES:

Using AI to improve standard-of-care cardiac imaging 

Stanford researchers develop novel "scaffold-free" approach for treating damaged muscles

Qubits created using unexpected materials

Superconductor advance could unlock ultra-energy-efficient electronics

Closing your eyes might not help you hear better after all

New computational biology tool automates and standardizes genome sequencing analysis

Climate change is fueling disease outbreaks

Three anesthesia drugs all have the same effect in the brain, MIT researchers find

Violence against women who inject drugs

Math can tell you how to manage your eczema

Adherence to healthy lifestyle and risk of cardiometabolic diseases in individuals with hypertension

Past intensive whaling threatens the future of bowhead whales

Thoughts don’t kill people, but study suggests options for keeping guns from doing so

Historian Lyndal Roper named 2026 Holberg Prize Laureate

Reconnecting kidney plumbing, the zebrafish way

Biologically inspired event camera for accurate passive vibration measurement

Single-cell transcriptomic analysis of the terminal ileum identifies BCMA as a therapeutic target in IgA nephropathy

Muscle-healing 'Ally' turns 'Enemy': A novel immune cell subset that controls muscle regeneration and ossification in FOP

Waterpipe smoking can cause carbon monoxide poisoning even after brief use, during outdoor smoking, or through indoor secondhand exposure

Impact of Japan's indoor smoke-free laws on the prevalence of smoke-free establishments

New study fills research gap in food safety to better protect pregnant people from Listeria

PFAS exposure may weaken teens’ bones

Researchers develop promising new therapy for most common form of bone cancer in children and young adults

FAU-FWC Study: Endangered smalltooth sawfish make a comeback in a historical Florida nursery

Towards highly efficient selective hydrogenation: the role of single-atom catalysts

A theory of Alzheimer's disease linking amyloid beta and tau

Ultra-processed foods linked with serious heart problems

Routine blood pressure readings offer early insights on dementia risk

Shingles vaccine drastically cuts risk of serious cardiac events

A new bird species in Japan

[Press-News.org] New research finds delaying surgical procedures increases infection risk and health care costs
Study in the Journal of the American College of Surgeons makes the case for performing more procedures on day of admission