PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

SLAS Technology April issue dives into reactive oxygen species

2021-04-01
(Press-News.org) Oak Brook, IL - The April edition of SLAS Technology features the cover article "Therapeutic Potential of Reactive Oxygen Species: State of the Art and Recent Advances" by Valeria Graceffa, Ph.D. (Institute of Technology Sligo, Sligo, Ireland).

The cover article explores the therapeutic potential of reactive oxygen species (ROS) including applications ranging from wound healing and hair growth enhancement, to cancer treatment, stem cell differentiation and tissue engineering. At low concentrations, ROS can be utilized as inexpensive and convenient inducers of tissue regeneration, triggering stem cell differentiation and enhancing collagen synthesis. Recent cancer studies have represented ROS as the 'Achilles Heels' of cancers given their high basal levels, leaving tumoral cells unable to sufficiently handle the additional source of oxidative stress. Because of this, higher doses of ROS are used for targeted killing of tumor cells. Lack of understanding of the technicalities between anabolic and cytotoxic effects means limited ROS clinical translation opportunities. While there is ample potential for the use of ROS, new strategies to control temporal pattern of ROS release have yet to be developed.

The April issue of SLAS Technology includes six articles of original research including:

Highly Versatile Cloud-Based Automation Solution for the Remote Design and Execution of Experiment Protocols during the COVID-19 Pandemic Metabolomic Signatures in Pediatric Crohn's Disease Patients with Mild or Quiescent Disease Treated with Partial Enteral Nutrition: A Feasibility Study Acoustic Ejection/Full-Scan Mass Spectrometry Analysis for High-Throughput Compound Plate Quality Control An Emerging Fluorescence-Based Technique for Quantification and Protein Profiling of Extracellular Vesicles Development of an Enhanced Throughput Radial Cell Migration Device A Variable Scheduling Maintenance Culture Platform for Mammalian Cells

Other articles include:

Application of Artificial Intelligence to Address Issues Related to the COVID-19 Virus Therapeutic Potential of Reactive Oxygen Species: State of the Art and Recent Advances Recent Developments in Bacterial Chemotaxis Analysis Based on the Microfluidic System Development of a Gold Nanoparticle-Based Colorimetric Sensor for Water for Injection At-Line Impurity Testing Integrating Mobile Robots into Automated Laboratory Processes: A Suitable Workflow Management System

INFORMATION:

Access to April's SLAS Technology issue is available at https://journals.sagepub.com/toc/jlad/26/2. For more information about SLAS and its journals, visit http://www.slas.org/journals.

SLAS (Society for Laboratory Automation and Screening) is an international professional society of academic, industry and government life sciences researchers and the developers and providers of laboratory automation technology. The SLAS mission is to bring together researchers in academia, industry and government to advance life sciences discovery and technology via education, knowledge exchange and global community building.

SLAS Discovery: Advancing the Science of Drug Discovery, 2019 Impact Factor 2.195. Editor-in-Chief Robert M. Campbell, Ph.D., Twentyeight-Seven Therapeutics, Boston, MA (USA).

SLAS Technology: Translating Life Sciences Innovation, 2019 Impact Factor 2.174. Editor-in-Chief Edward Kai-Hua Chow, Ph.D., National University of Singapore (Singapore).



ELSE PRESS RELEASES FROM THIS DATE:

UTSA criminology professor studies impact of COVID-19on gender-based violence

2021-04-01
(APRIL 1, 2021) -The pandemic has exacerbated risk factors for gender-based violence, such as unemployment and financial strain, substance use, isolation, depression anxiety, and general stress, according to the American Psychological Association. That's inspired The University of Texas at San Antonio criminology and criminal justice professor Kellie Lynch, along with professor TK Logan from the University of Kentucky, to work with the National Coalition Against Domestic Violence on a national survey to investigate the impact of the COVID-19 pandemic on the dynamics of gender-based violence and the experiences of those serving victims of gender-based violence. "The consequences of the COVID-19 pandemic are far-reaching and we still have much to learn about ...

Medical studies without adequate pre-publication review could damage public trust in science

2021-04-01
The public could lose trust in science if scientific and medical researchers choose to bypass the traditional high standards of peer-reviewed medical journals in the rush to get research data released, particularly during crises such as the COVID-19 pandemic. That's the warning from three leading medical communications organizations, that have published a joint statement in the peer-reviewed journal Current Medical Research and Opinion - asserting that the integrity of published scientific and medical research must be protected. Out today, the joint statement from the American Medical ...

The Lancet GH: COVID-19 pandemic worsened pregnancy outcomes for women and babies worldwide

2021-04-01
Review of 40 published studies from 17 countries offers first global assessment of the collateral impact of the COVID-19 pandemic on pregnancy outcomes. Findings reveal overall increase in the chances of stillbirth and maternal death during the pandemic, but chances of pre-term birth decreased in high-income countries. Women requiring surgery for ectopic pregnancies increased almost six-fold during the pandemic across all studies, after accounting for the size of included studies (surgery rate for ectopic pregnancies during pandemic 27/37 vs pre-pandemic 73/272), and symptoms of maternal depression were also increased. Study reveals disproportionate impact ...

Will US public support donating COVID-19 vaccines to low- and middle-income countries?

2021-04-01
The pandemic is affecting every country, but not every country has equal access to the lifesaving COVID-19 vaccines. Recent estimates show that high-income countries -- which have just one-fifth of the global adult population -- have purchased more than half of the world's total vaccine doses, resulting in disparities for low- and middle-income countries. A new study by researchers at Virginia Commonwealth University investigates a key question: Will the U.S. population support donating part of its COVID-19 vaccine stockpile to less prosperous countries? "COVID-19 is a true global pandemic that has touched every nation ...

Houston Methodist among largest providers of monoclonal antibody treatment for COVID-19

2021-04-01
Houston Methodist has been a leader in successfully treating high-risk patients with monoclonal antibodies (mAB) for mild to moderate Covid-19 infection. Among the nation's largest providers of mAB therapy, Houston Methodist has infused nearly 4,000 patients since the FDA's Emergency Use Authorization (EUA) was issued. The hospital system was able to quickly ramp up its program once the EUA was granted by leveraging a number of resources through interdisciplinary collaboration. As more hospitals begin to ramp up for treating Covid-19 with mAB therapy, Houston Methodist's example serves as a valuable model for other medical systems to establish or expand mAB treatment programs and improve patient access to this critical therapy. A commentary outlining the challenges, ...

CU Cancer Center researcher reveals new effects of oxygen deprivation in cancer cells

CU Cancer Center researcher reveals new effects of oxygen deprivation in cancer cells
2021-03-31
A team of University of Colorado School of Medicine researchers recently published a paper offering new insight into the role that oxygen deprivation, or hypoxia, plays in cancer development. CU Cancer Center member Joaquin Espinosa, PhD, is the senior researcher on the paper, which he hopes will help lead to more targeted treatments for cancer.  For their paper published this month in the journal Nature Communications, Espinosa and the rest of the team -- Zdenek Andrysik, PhD; Heather Bender, PhD; and Matthew Galbraith, PhD -- used state-of-the-art genomics technologies to map the response of cancer cells to hypoxia with unprecedented detail, ...

Novel pharmacological strategies to treat alcoholism. Focus on epigenetics

Novel pharmacological strategies to treat alcoholism. Focus on epigenetics
2021-03-31
Abusive alcohol drinking considerably impacts human health. Alcoholism, better defined as Alcohol Use Disorders (AUD), includes a group of pathological entities related to alcohol-induced damage. Individuals with AUD exhibit compulsive alcohol drinking and negative emotional states when alcohol drinking ceases. In the most severe AUD forms, the individuals lose control over consumption despite a decided will to stop. Some controversial issues have arisen as to whether the definition of AUD can help to delimit and characterize clinical entities related to abusive alcohol ingestion. The World Health Organization (WHO) reports that approximately 3,3 million people (5,9% of global ...

COVID-19 antibody tests, even rapid finger pricks, are effective, new study finds

2021-03-31
New findings from a Michigan Medicine study reveal that antibody testing is predictive of prior COVID-19 infection, and rapid screening methods - even from finger pricks - are effective testing tools. Researchers analyzed antibody tests conducted on more than 500 subjects in patient care settings. They found that people who had COVID, including those with mild symptoms, produced antibodies. "For a long time, people were very worried that people with mild COVID did not make immune responses," says Charles Schuler, M.D., a clinical assistant professor of allergy and immunology at Michigan Medicine. "This should give people confidence that the tests that are available to them aren't just random number generators. They're actually giving them ...

Soft "sweat stickers" may streamline diagnosis of cystic fibrosis in children

2021-03-31
New "sweat stickers" may streamline the early diagnosis of cystic fibrosis by enabling scientists to easily gather and analyze sweat from the skin of infants and children. The stickers matched the performance of previous, more cumbersome devices when tested with 51 subjects, suggesting the stickers could address design obstacles that have held back the diagnosis and treatment of cystic fibrosis in pediatric patients. Diagnosing cystic fibrosis in infancy or childhood is critical to achieve good outcomes, as current treatments must be given early to extend lifespans and alter the course of the disease. Many current diagnostics work by detecting levels of chloride in sweat, which are elevated in cystic fibrosis patients. However, these tests must often be repeated and use unwieldy wrist-wrapped ...

Mothers bear the cost of the pandemic shift to remote work

2021-03-31
For many parents, the COVID-19 pandemic has made life's everyday juggling act--managing work, school, extracurricular, and household responsibilities--much, much harder. And according to a new study led by Penn sociologists, those extra burdens have fallen disproportionately on mothers. The research, shared in the April issue of the journal Gender and Society, investigated how shifts in work and school that arose due to the pandemic triggered changes in the division of labor in families. Using data on two-parent households from a nationwide survey conducted in April 2020, the researchers found that ...

LAST 30 PRESS RELEASES:

Science reveals why you can’t resist a snack – even when you’re full

Kidney cancer study finds belzutifan plus pembrolizumab post-surgery helps patients at high risk for relapse stay cancer-free longer

Alkali cation effects in electrochemical carbon dioxide reduction

Test platforms for charging wireless cars now fit on a bench

$3 million NIH grant funds national study of Medicare Advantage’s benefit expansion into social supports

Amplified Sciences achieves CAP accreditation for cutting-edge diagnostic lab

Fred Hutch announces 12 recipients of the annual Harold M. Weintraub Graduate Student Award

Native forest litter helps rebuild soil life in post-mining landscapes

Mountain soils in arid regions may emit more greenhouse gas as climate shifts, new study finds

Pairing biochar with other soil amendments could unlock stronger gains in soil health

Why do we get a skip in our step when we’re happy? Thank dopamine

UC Irvine scientists uncover cellular mechanism behind muscle repair

Platform to map living brain noninvasively takes next big step

Stress-testing the Cascadia Subduction Zone reveals variability that could impact how earthquakes spread

We may be underestimating the true carbon cost of northern wildfires

Blood test predicts which bladder cancer patients may safely skip surgery

Kennesaw State's Vijay Anand honored as National Academy of Inventors Senior Member

Recovery from whaling reveals the role of age in Humpback reproduction 

Can the canny tick help prevent disease like MS and cancer?

Newcomer children show lower rates of emergency department use for non‑urgent conditions, study finds

Cognitive and neuropsychiatric function in former American football players

From trash to climate tech: rubber gloves find new life as carbon capturers materials

A step towards needed treatments for hantaviruses in new molecular map

Boys are more motivated, while girls are more compassionate?

Study identifies opposing roles for IL6 and IL6R in long-term mortality

AI accurately spots medical disorder from privacy-conscious hand images

Transient Pauli blocking for broadband ultrafast optical switching

Political polarization can spur CO2 emissions, stymie climate action

Researchers develop new strategy for improving inverted perovskite solar cells

Yes! The role of YAP and CTGF as potential therapeutic targets for preventing severe liver disease

[Press-News.org] SLAS Technology April issue dives into reactive oxygen species