Study shows tanning bed ban would reduce skin cancer rates in minors and cut healthcare costs

Workplace communication often took a back seat this past year, as employees and employers rushed to work remotely, struggled with technology barriers and adjusted to physical distancing. But the pandemic has resulted in valuable lessons for communicating on the job, according to a Baylor University study. During the onset of COVID-19 -- along with accompanying layoffs and a recession -- "there likely has never been a moment with such demand for ethical listening to employees," said lead author Marlene S. Neill, Ph.D., associate professor of journalism, public relations and new media at Baylor. "Ethical listening" was defined by one communication ...

April12, 2021 - Gray wolves are among the largest predators to have survived the extinction at the end of the last ice age around11,700 years ago. Today, they can be found roaming Yukon's boreal forest and tundra, with caribou and moose as their main sources of food. A new study led by the Canadian Museum of Nature shows that wolves may have survived by adapting their diet over thousands of years---from a primary reliance on horses during the Pleistocene, to caribou and moose today. The results are published in the journal Palaeogeography, Palaeoclimatology, Palaeoecology. The research team, led by museum palaeontologist Dr. Danielle Fraser and student Zoe Landry, analysed evidence preserved in ...

HOUSTON -- Early phase clinical trials conducted by researchers from The University of Texas MD Anderson Cancer Center show promising results for patients with RET fusion-positive cancers, high-grade (HGG) and low-grade glioma (LGG) and ovarian cancer. The results, presented today at the virtual American Association for Cancer Research (AACR) Annual Meeting 2021, showcase the researchers' ongoing efforts to advance clinical studies and expand potential indications of approved drugs to develop a platform for more effective treatments and to improve patient outcomes. FDA-approved selpercatinib shows clinical benefits for RET fusion-positive ...

PHILADELPHIA--Giving early-stage pancreatic cancer patients a CD40 immune-stimulating drug helped jumpstart a T cell attack to the notoriously stubborn tumor microenvironment before surgery and other treatments, according to a new study from researchers in the Abramson Cancer Center (ACC) at the University of Pennsylvania. Changing the microenvironment from so-called T cell "poor" to T cell "rich" with a CD40 agonist earlier could help slow eventual progression of the disease and prevent cancer from spreading in more patients. The data--which included 16 ...

LOS ANGELES -- Early results from a new, pioneering chimeric antigen receptor (CAR) T cell immunotherapy trial led by researchers at the UCLA Jonsson Comprehensive Cancer Center found using a bilateral attack instead of the conventional single-target approach helps minimizes treatment resistance, resulting in long-lasting remission for people with non-Hodgkin's B-cell lymphoma that has come back or has not responded to treatment. The new approach, which will be presented at the American Association for Cancer Research Annual Meeting during one of the clinical oral plenary sessions ( END ...

New York, NY (April 10, 2021) - A personalized cancer vaccine developed with the help of a Mount Sinai computational platform raised no safety concerns and showed potential benefit in patients with different cancers, including lung and bladder, that have a high risk of recurrence, according to results from an investigator-initiated phase I clinical trial presented during the virtual American Association for Cancer Research (AACR) Annual Meeting 2021, held April 10-15. "While immunotherapy has revolutionized the treatment of cancer, the vast majority of patients do not experience a significant clinical response with such treatments," said study author Thomas Marron, MD, PhD, Assistant Director for Early Phase and Immunotherapy Trials ...

HOUSTON - Researchers at The University of Texas MD Anderson Cancer Center have discovered that mutant KRAS and p53, the most frequently mutated genes in pancreatic cancer, interact through the CREB1 protein to promote metastasis and tumor growth. Blocking CREB1 in preclinical models reversed these effects and reduced metastases, suggesting an important new therapeutic target for the deadly cancer. The findings were published today in Cancer Discovery and presented at the virtual American Association for Cancer Research (AACR) Annual Meeting 2021 by Michael Kim, M.D., ...

Research from Queen Mary University of London has revealed novel insights into the effects of chemotherapy on the tumour microenvironment (TME). The study, published today in Cancer Immunology Research, a journal of the American Association for Cancer Research, found that chemotherapy enhances the anti-tumour actions of immune cells within the TME and their ability to support immune responses against cancer. Cancers are not just a mass of cancerous cells, but are rogue organs made up of many different cell types, including cells that form connective tissue and blood vessels, and immune cells. These non-cancerous cells have been recruited and corrupted by the cancer to help it grow and spread, and constitute what ...

Patients with non-small cell lung cancer (NSCLC) whose cancer cells have low levels of aneuploidy - an abnormal number of chromosomes - tend to respond better to immune checkpoint inhibitor drugs than patients with higher levels, Dana-Farber Cancer Institute researchers will report at the virtual AACR Annual Meeting 2021. In analyzing data from hundreds of patients with NSCLC who were treated with these drugs, the researchers found that those whose cancer receded tended to have less aneuploidy in their tumor cells than those whose disease remained stable or worsened. These findings suggest that aneuploidy testing can have an important role in determining which ...

Tokyo, Japan - Researchers from Tokyo Metropolitan University have shown that a quantity known as "thermoelectric conductivity" is an effective measure for the dimensionality of newly developed thermoelectric nanomaterials. Studying films of semiconducting single-walled carbon nanotubes and atomically thin sheets of molybdenum sulfide and graphene, they found clear distinctions in how this number varies with conductivity, in agreement with theoretical predictions in 1D and 2D materials. Such a metric promises better design strategies for thermoelectric materials. Thermoelectric devices take differences in temperature between different materials and generate electrical energy. The simplest example is two strips of ...