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Medicine 2021-04-10 1 min read

New CAR T approach minimizes resistance, helps avoid relapse in non-Hodgkin's B-cell lymphoma

UCLA clinical trial shows bispecific CAR T cells targeting CD19/CD20 are safe and effective in patients with relapsed or refractory B-cell lymphoma
Published 2021-04-10 · Original archive entry · Explore research explainers
LOS ANGELES -- Early results from a new, pioneering chimeric antigen receptor (CAR) T cell immunotherapy trial led by researchers at the UCLA Jonsson Comprehensive Cancer Center found using a bilateral attack instead of the conventional single-target approach helps minimizes treatment resistance, resulting in long-lasting remission for people with non-Hodgkin's B-cell lymphoma that has come back or has not responded to treatment.

The new approach, which will be presented at the American Association for Cancer Research Annual Meeting during one of the clinical oral plenary sessions ( END
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