National report highlights benefit of collaborative care models for people with dementia
Research and implementation by Regenstrief research scientists cited in report
2021-04-19
(Press-News.org) INDIANAPOLIS -- A new report from the National Academies of Sciences, Engineering, and Medicine (National Academies) details the state of dementia care and research in America and provides guidance on future research to make sure both patients and their families are having their needs met by the care they receive. Sections of the report highlight the effectiveness of the collaborative care model as well as successful implementation, citing research from Regenstrief Institute, Eskenazi Health and the Indiana University School of Medicine.
There are between 3.7 million and 5.8 million people living with dementia in the United States, and that number is likely to grow as the population ages.
The report, Meeting the Challenge of Caring for Persons Living with Dementia and Their Care Partners and Caregivers: A Way Forward, sponsored by the National Institutes of Health's National Institute on Aging, looked at the various needs of people with dementia, including help with medication use, paying bills and managing day-to-day activities. It notes several limitations of current care interventions. However, based on an independent systematic review by the Agency for Healthcare Research and Quality, found two types of interventions that are supported by low-strength evidence of benefit: collaborative care models, which integrate medical and psychosocial care; and Resources for Enhancing Alzheimer's Caregiver Health (REACH) II, an intervention aimed at supporting family caregivers.
Regenstrief Research Scientist and IU School of Medicine Professor of Medicine Christopher Callahan, M.D., was a member of the committee that compiled the report. He has worked extensively with colleagues at Regenstrief, IU and Eskenazi Health on developing and implementing collaborative care models for Alzheimer's disease. Improving care for persons living with dementia and their care partners is an important research focus for a large team of scientists in the Center for Aging Research at the Regenstrief Institute.
"This report incorporated feedback from people with dementia and their families, and they indicated that outcomes measured by past research have been too narrow and there are other areas of wellbeing that are important to them that have not been taken into consideration," said Dr. Callahan. "Collaborative care works to provide holistic care to the patients and their families, and the model can be adapted to address needs that are not currently being met."
Collaborative care models integrate medical and psychosocial care, delivered by a team of providers including physicians, nurses, psychologists, care coordinators and social workers. This model has proven to significantly improve patient and caregiver outcomes and reduce costs and has been successfully implemented at the Sandra Eskenazi Center for Brain Care Innovation.
The National Academies report highlighted the urgent need to put into practice evidence-based interventions, referencing the work of Regenstrief Research Scientist and IU School of Medicine Professor Malaz Boustani, M.D., MPH. Dr. Boustani is creating strategies for more trials that take place in real-world situations, while still being rigorous in testing important outcomes.
"Patients and families indicated that they understand that interventions will not be perfect, but they want them implemented now, in the real world, while research and refinement continues," said Dr. Callahan.
The report proposes a blueprint for future research, which includes methodological improvements and approaches that can complement randomized control trials. A major focus should be assessing real-world effectiveness and prioritizing inclusive research.
INFORMATION:
Read the report here: https://www.nap.edu/catalog/26026/meeting-the-challenge-of-caring-for-persons-living-with-dementia-and-their-care-partners-and-caregivers.
More information the Sandra Eskenazi Center for Brain Care Innovation: https://www.eskenazihealth.edu/health-services/brain-center
More information on Alzheimer's and resources:https://www.alz.org/
Get involved in research: https://medicine.iu.edu/research-centers/alzheimers
About Regenstrief Institute
Founded in 1969 in Indianapolis, the Regenstrief Institute is a local, national and global leader dedicated to a world where better information empowers people to end disease and realize true health. A key research partner to Indiana University, Regenstrief and its research scientists are responsible for a growing number of major healthcare innovations and studies. Examples range from the development of global health information technology standards that enable the use and interoperability of electronic health records to improving patient-physician communications, to creating models of care that inform practice and improve the lives of patients around the globe.
Sam Regenstrief, a nationally successful entrepreneur from Connersville, Indiana, founded the institute with the goal of making healthcare more efficient and accessible for everyone. His vision continues to guide the institute's research mission.
About IU School of Medicine
IU School of Medicine is the largest medical school in the U.S. and is annually ranked among the top medical schools in the nation by U.S. News & World Report. The school offers high-quality medical education, access to leading medical research and rich campus life in nine Indiana cities, including rural and urban locations consistently recognized for livability.
About Christopher Callahan, M.D.
In addition to his role as a research scientist at Regenstrief Institute, Christopher M. Callahan, M.D., is chief research and development officer at Eskenazi Health and a professor of medicine at Indiana University School of Medicine.
[Attachments] See images for this press release:
ELSE PRESS RELEASES FROM THIS DATE:
2021-04-19
Scientists have sequenced ancient DNA from soil for the first time and the advance will transform what is known about everything from evolution to climate change.
The findings have been described as the 'moon landings' of genomics because researchers will no longer have to rely on finding and testing fossils to determine genetic ancestry, links and discoveries - and it is thanks to Stone Age black bears who defecated in a remote cave in Mexico 16,000 years ago.
A team of scientists from The Lundbeck Foundation GeoGenetics Centre, University of Copenhagen, led by Professor Eske Willerslev, director of the foundation and a Fellow of St John's College, University of Cambridge, recreated ...
2021-04-19
April 19, 2021 - An estimated 50 million people undergo surgery each year in the United States, and a significant proportion of them have undiagnosed or untreated sleep disorders (SD) or sleep-disordered breathing (SDB). Issues at the intersection of anesthesiology and sleep medicine are the focus of the Society of Anesthesia and Sleep Medicine (SASM) whose 10th anniversary is commemorated in the special theme May issue of Anesthesia & Analgesia.
The special issue looks back at a remarkable first decade of achievements in research and clinical practice by this young subspecialty society, while looking forward to further progress. A key ...
2021-04-19
More blood thinners aren't automatically better, another study confirms.
A new publication in JAMA Internal Medicine focuses on the minimal pros and the concerning cons of combining a daily aspirin with a drug from the newer class of anticoagulants that include apixaban, dabigatran, edoxaban and rivaroxaban.
Patients were taking one of these direct oral anticoagulants known as DOACs to prevent strokes from non-valvular atrial fibrillation or for the treatment of venous thromboembolic disease (deep vein thrombosis or pulmonary embolism). The included patients did not have another reason to take aspirin ...
2021-04-19
PHILADELPHIA - A new gene therapy for one of the most common forms of congenital blindness was safe and improved patients' vision, according to initial data from a clinical trial led by researchers at the Scheie Eye Institute in the Perelman School of Medicine at the University of Pennsylvania.
The therapy delivers working copies of GUCY2D to the eyes of patients who have severe vision impairments caused by mutations in the gene. Each of the first three treated patients experienced improvement in some aspects of vision, without serious side effects, according to the new study, published in the journal iScience.
"We found sustained improvements in both day and night vision, even with a relatively low dose of the gene therapy," said study lead author Samuel G. Jacobson, MD, ...
2021-04-19
A new study outlines the need for materials advances in the hardware that goes into making quantum computers if these futuristic devices are to surpass the abilities of the computers we use today.
The study, published in the journal Science by an international team, surveyed the state of research on quantum computing hardware with the goal of illustrating the challenges and opportunities facing scientists and engineers.
While conventional computers encode "bits" of information as ones and zeroes, quantum computers breeze past this binary arrangement by creating "qubits," which can be complex, continuous quantities. Storing and manipulating information ...
2021-04-19
JACKSONVILLE, Fla. -- In a new paper published in Nature Communications, Mayo Clinic researchers and collaborators report the protein-coding gene SERPINA5 may worsen tau protein tangles, which are characteristic of Alzheimer's disease, and advance disease. By combining clinical expertise, brain tissue samples, pathology expertise and artificial intelligence, the team clarified and validated the relevance of the gene to Alzheimer's disease.
The researchers used tissue samples from 385 brains donated to the Mayo Clinic Brain Bank, which houses more than 9,000 brain tissue specimens for the study of neurodegenerative disorders. The samples were from people who were diagnosed with Alzheimer's disease and lacked co-existing diseases found in ...
2021-04-19
Hydrogen will be needed in large quantities as an energy carrier and raw material in the energy system of the future. To achieve this, however, hydrogen must be produced in a climate-neutral way, for example through so-called photoelectrolysis, by using sunlight to split water into hydrogen and oxygen. As photoelectrodes, semiconducting materials are needed that convert sunlight into electricity and remain stable in water. Metal oxides are among the best candidates for stable and inexpensive photoelectrodes. Some of these metal oxides also have catalytically active surfaces that accelerate the formation of hydrogen at the cathode or oxygen at the anode.
Why is rust not much better?
Research has long focused on haematite (α-Fe2O3), ...
2021-04-19
MINNEAPOLIS - April 19, 2021 - Despite access to some of the best possible medical care in the world, Senators John McCain and Edward Kennedy both died within 18 months of their diagnosis of glioblastoma, an aggressive form of brain cancer. While this deadly outcome typifies the nature of this disease, some glioblastoma patients see exceptional benefits from chemotherapy and survive beyond expectations. Why this happens has been revealed by researchers at the University of Minnesota in a new study published in the Proceedings of the National Academy of Sciences.
"Deciphering the molecular underpinning of these exceptional ...
2021-04-19
In March 2020, when the pandemic hit, everything slowed, including non-essential medical procedures such as elective surgeries, to reduce the spread of the coronavirus.
Six weeks later, Mary Byrnes, Ph.D., an assistant research scientist in the Department of Surgery at Michigan Medicine, began calling University of Michigan Frankel Cardiovascular Center patients whose surgeries had been canceled or delayed. She wanted to hear about their experiences -- what undergoing surgery meant to them, how postponing their operations had affected them, whether the existence of the coronavirus complicated how they felt about their bodies and ...
2021-04-19
Psoriasis is a common inflammatory skin condition. The underlying genetic factors have not yet been sufficiently researched. The skin inflammation is usually triggered by external factors such as infections or stress. A research team at the Institute of Cancer Research of the Medical University of Vienna has now managed to identify a new factor in signal transmission of the immune system that plays a major role in the development of a psoriatic episode. The scientists have shown that symptoms can be alleviated by inhibiting the "c-Jun" protein in signal transmission.
The common clinical manifestation of psoriasis is a pinkish-grey thickening of the epidermis in distinct foci of infection, ...
LAST 30 PRESS RELEASES:
[Press-News.org] National report highlights benefit of collaborative care models for people with dementia
Research and implementation by Regenstrief research scientists cited in report
