Using contrast MRI after a heart attack could increase survival
2021-05-11
(Press-News.org) According to the British Heart Foundation, heart and circulatory diseases cause more than a quarter (27 per cent) of all deaths in the UK, which equates to more than 160,000 deaths each year - or one death every three minutes.
The research, published in the top science journal Advanced Science, found that injection of the trace mineral manganese could enhanced MRI scans so that they provided more accurate details of heart function than traditional MRI methods.
These findings, if confirmed in human subjects, could have major implications for the treatment of heart attack patients. The findings could also be of great use in the preclinical evaluation of treatments for patients who suffer from cardiac ischemia - a reduction in blood supply to the heart muscle that could lead to cardiac arrest.
The study also suggests that if manganese-enhanced MRI is performed within the first few hours of a heart attack it could be used to determine the optimal treatment regime for individual patients - helping to regulate changes in the cardiac muscle and thereby further improving survival chances. Findings were evaluated by examining the infarct size and blood supply at three key intervals: one hour, one day and 14 days after a myocardial infarction was induced.
Dr Patrizia Camelliti, Principal Investigator and Senior Lecturer in Cardiovascular Science at the University of Surrey, said:
"Magnetic resonance imaging (MRI) is increasingly used to diagnose and give information on heart conditions. This research using mice allows us to measure the health status of the heart muscle rapidly after a heart attack and could provide important information for optimising treatments in patients".
INFORMATION:
Note to editors
The study was performed using animal subjects.
ELSE PRESS RELEASES FROM THIS DATE:
2021-05-11
By combining two medications, researchers at Michigan Medicine optimized a therapy for people with gout, a condition that causes severe damage and disability if left untreated.
The study revealed how a second drug taken orally more than doubled the effectiveness of Pegloticase, an intravenous gout treatment used to dissolve crystalized uric acid in the joints when oral medications fail.
"Gout is a challenging disease to treat because there are only a handful of oral therapies to lower uric acid," says Puja Khanna, M.D., M.P.H., a rheumatologist at Michigan Medicine. "Now, we have a medication that works and gives us a ...
2021-05-11
New guidelines for coral reef restoration aiming to reduce the risk of flooding in tropical coastal communities have been set out in a new study that simulated the behavior of ocean waves travelling over and beyond a range of coral reef structures. Published in Frontiers in Marine Science, these guidelines hope to optimize restoration efforts not only for the benefit of the ecosystem, but also to protect the coast and people living on it.
"Our research reveals that shallow, energetic areas such as the upper fore reef and middle reef flat, typically characterized by physically-robust coral species, should be targeted for restoration to reduce coastal flooding," says Floortje Roelvink, lead author on the paper and researcher at Deltares, a Dutch research ...
2021-05-11
Obsessive-compulsive disorder (OCD) in children and adolescents is associated with impaired education and worse general health later in life. Access to specialist treatment is often limited. According to a study from Centre for Psychiatry Research at Karolinska Institutet in Sweden and Region Stockholm, internet-delivered cognitive behavioural therapy (CBT) can be as effective as conventional CBT. The study, published in the prestigious journal JAMA, can help make treatment for OCD more widely accessible.
Obsessive-compulsive disorder (OCD) is a potentially serious mental disorder that normally debuts in childhood.
Symptoms include intrusive thoughts that trigger anxiety ...
2021-05-11
Toxicity and Challenges in Transferability of Surface-functionalized Metallic Nanoparticles
https://doi.org/10.15212/bioi-2020-0047
Announcing a new article publication for BIO Integration journal. In this review the authors Muhammad Arif Asghar, Rabia Ismail Yousuf, Muhammad Harris Shoaib, Muhammad Arif Asghar and Nazish Mumtaz from Jinnah Sindh Medical University, Karachi, Pakistan, University of Karachi, Karachi, Pakistan, Food and Marine Resources Research Centre, Pakistan and Benazir Bhutto Shaheed University, Karachi, Pakistan discuss toxicity and challenges in transferability of surface-functionalized metallic nanoparticles from animal models to humans.
The unique size and surface morphology of nanoparticles ...
2021-05-11
A new drug combination that is better at treating miscarriage is also more cost effective than current standard NHS treatment, finds a new study led by the University of Birmingham and Tommy's National Centre for Miscarriage Research.
A previous study by the same team and published in The Lancet * in August last year, found that a combined drug treatment is more effective than the standard medication for women having miscarriages without symptoms - also known as missed, delayed or silent miscarriage.
Missed miscarriage occurs when a baby has died in the womb but the mother hasn't ...
2021-05-11
A study by the University of Southampton has shown its LifeLab programme, aimed at improving adolescent health through hands-on learning, significantly increases young people's understanding of what it means to lead a healthy lifestyle.
Led by a team from both the Faculty of Medicine and Education School at the University of Southampton, the LifeLab programme aims to encourage engagement with the science behind public health messages, to support development of health literacy alongside decision-making skills and promotion of adolescents' sense of control over their lives and futures. Based at University Hospital Southampton (UHS) NHS Foundation Trust, LifeLab is a state-of-the-art teaching laboratory ...
2021-05-11
The COVID-19 pandemic has now claimed over 2 million deaths worldwide, and this number is only increasing. In response, health agencies have rolled out tests to diagnose and understand the disease. Besides the now widely known PCR test, there is interest in serological (blood) tests that detect "antibodies" against SARS-CoV-2, the virus that causes COVID-19. These blood tests have considerable applications, from identifying blood donors with high levels of anti-SARS-CoV-2 antibodies, whose blood can be used for convalescent plasma therapy, to measuring vaccine effectiveness.
So, what are antibodies? These are proteins produced by the ...
2021-05-11
This rare fossil find comes from the Kimmeridge Clay Formation in England, a series of sedimentary rocks that was formed in a shallow, tropical-subtropical sea during the Upper Jurassic, about 150 million years ago. The fossil shark skeleton was found more than 20 years ago on the southern coast of England and is now held in the Etches Collection. Additional fossil shark specimens from it will be investigated in the years to come.
Due to their life-long tooth replacement shark teeth are among the most common vertebrate finds encountered in the fossil record. The low preservation potential of their poorly mineralized cartilaginous skeletons, on the ...
2021-05-11
A scientist from HSE University has developed an image recognition algorithm that works 40% faster than analogues. It can speed up real-time processing of video-based image recognition systems. The results of the study have been published in the journal Information Sciences.
Convolutional neural networks (CNNs), which include a sequence of convolutional layers, are widely used in computer vision. Each layer in a network has an input and an output. The digital description of the image goes to the input of the first layer and is converted into a different set of numbers at the output. The result goes to the input of ...
2021-05-11
Wastewater testing is an effective way to identify new cases of COVID-19 in nursing homes and other congregate living settings, and it may be particularly useful for preventing outbreaks in college dormitories, a new University of Virginia study finds.
The research, a collaboration of UVA's School of Medicine and School of Engineering, was led by UVA Health's Amy Mathers, MD. It offers some of the first clear guidance on the most effective methods to perform testing to detect COVID-19 in wastewater.
The researchers evaluated and compared sampling and analysis techniques by testing them within buildings with known numbers of positive cases. They were then able to determine wastewater testing's strengths and limitations as a tool for monitoring COVID-19 in a building population. ...
LAST 30 PRESS RELEASES:
[Press-News.org] Using contrast MRI after a heart attack could increase survival
