PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Stair climbing offers significant cardiovascular and muscular benefits for heart patients

2021-05-17
(Press-News.org) A team of McMaster University researchers who studied heart patients found that stair-climbing routines, whether vigorous or moderate, provide significant cardiovascular and muscular benefits.

The findings, published in closely related studies in the journals Medicine & Science in Sports & Exercise and Frontiers, address the most frequently cited barriers to exercise: time, equipment and access to gym facilities.

"Brief, vigorous stair-climbing and traditional moderate intensity exercise both changed fitness, which is a key predictor of mortality after a cardiac event," says Maureen MacDonald, one of the lead researchers on both studies and a professor in McMaster's Department of Kinesiology.

"We've shown stair-climbing is a safe, efficient and feasible option for cardiac rehabilitation, which is particularly relevant during the pandemic when many people don't have the option to exercise in a gym," she says.

While it is widely known that exercise and lifestyle changes reduce the risk of secondary cardiovascular disease, statistics suggest less than a quarter of all cardiac patients adhere to fitness programs.

Researchers worked closely with the Cardiac Health and Rehabilitation Centre at the Hamilton General Hospital to develop an exercise protocol that did not require specialized equipment or monitoring and could be easily performed outside a laboratory.

Participants with coronary artery disease who had undergone a cardiac procedure were randomly assigned either to traditional moderate-intensity exercise or vigorous stair climbing: three rounds of six flights of 12 stairs, separated by recovery periods of walking, with participants selecting their own stepping pace.

Researchers compared the results and found that individuals who had done traditional exercise and those who had done stair-climbing both increased their cardiorespiratory fitness after four weeks of supervised training and maintained those levels for an additional eight weeks of unsupervised training.

They also reported substantial muscular improvement.

"These patients who had undergone a coronary bypass or stent procedure had muscle that was compromised, compared to age-matched healthy controls," explained Stuart Phillips, a co-author of the studies and a professor in the Department of Kinesiology at McMaster who oversaw the analysis of muscle tissue taken during the study.

Previously, there had been very few studies of the impact of exercise on cardiac patients' muscle specifically. This analysis shows heart patients can still repair and build lost muscle.

"Even in just a short period, whether it was moderate intensity, continuous training or high-intensity stair climbing, there were beneficial adaptations in muscles after a cardiac procedure," Phillips says. "The improvements were clear."

INFORMATION:

Attention editors: A copy of the research papers can be found at the following links:

https://journals.lww.com/acsm-msse/Abstract/2021/06000/Both_Traditional_and_Stair_Climbing_based_HIIT.2.aspx

https://www.frontiersin.org/articles/10.3389/fspor.2021.630912/full



ELSE PRESS RELEASES FROM THIS DATE:

Oncotarget: CABYR-a/b and CABYR-c hold promise as targets for specific immunotherapy

Oncotarget: CABYR-a/b and CABYR-c hold promise as targets for specific immunotherapy
2021-05-17
Oncotarget published "The cancer testis antigens CABYR-a/b and CABYR-c are expressed in a subset of colorectal cancers and hold promise as targets for specific immunotherapy" which reported that Calcium-binding tyrosine phosphorylation-regulated protein is expressed in the human germ line but not in adult human tissues, thus, it is considered a cancer testis protein. The aim of this study is to evaluate the CABYR isoforms: a/b and c mRNA expression in colorectal cancer and to determine if these proteins hold promise as vaccine targets. CABYR mRNA expression in a set of normal human tissues, including the testis, were determined ...

COVID-19 vaccination: Thrombosis can be prevented by prompt treatment

2021-05-17
A rare syndrome has been observed in people following vaccination against Covid-19. This involves thrombosis at unusual sites in the body, associated with a low thrombocyte (blood platelet) count and a clotting disorder. In medical jargon, this syndrome is referred to as VITT (vaccine-induced thrombotic thrombocytopenia). Doctors at the Department of Medicine I of MedUni Vienna and Vienna General Hospital (Division of Hematology and Hemastaseology) have now successfully treated an acute instance of this syndrome. VITT is most probably caused by a defective immune response, whereby thrombocyte-activating antibodies are produced resulting ...

New epigenetic regulatory mechanisms involved in multiple myeloma growth

New epigenetic regulatory mechanisms involved in multiple myeloma growth
2021-05-17
An international team of researchers from Japan, the US and the UK has analyzed the function of the histone demethylase KDM5A in multiple myeloma, one of the three major hematological cancers, and clarified the mechanism by which it promotes myeloma cell proliferation. They also developed a novel KDM5 inhibitor and showed that it inhibits cancer cell growth in a myeloma mouse model. The researchers expect that new therapies targeting KDM5A will be developed in the future. The prognosis for multiple myeloma is improving every year with the introduction of new ...

Gut hormone triggers craving for more proteins

Gut hormone triggers craving for more proteins
2021-05-17
A new study led by KAIST researchers using fruit flies reveals how protein deficiency in the diet triggers cross talk between the gut and brain to induce a desire to eat foods rich in proteins or essential amino acids. This finding reported in the May 5 issue of Nature can lead to a better understanding of malnutrition in humans. "All organisms require a balanced intake of carbohydrates, proteins, and fats for their well being," explained KAIST neuroscientist and professor Greg Seong-Bae Suh. "Taking in sufficient calories alone won't do the job, as it can still lead to severe forms of malnutrition including kwashiorkor, if the diet does not include enough proteins," he added. Scientists already knew that inadequate ...

Two biodiversity refugia identified in the Eastern Bering Sea

Two biodiversity refugia identified in the Eastern Bering Sea
2021-05-17
Scientists from Hokkaido University have used species survey and climate data to identify two marine biodiversity refugia in the Eastern Bering Sea - regions where species richness, community stability and climate stability are high. Marine biodiversity, the diversity of life in the seas and oceans, supports ecosystem services of immense societal benefits. However, climate change and human activities have been adversely affecting marine biodiversity for many decades, resulting in population decline, community shifts, and species loss and extinction. Developing effective means to mitigate ...

Cysteinylated albumin: A new early diagnostic marker for diabetic kidney disease

Cysteinylated albumin: A new early diagnostic marker for diabetic kidney disease
2021-05-17
A research group from Kumamoto University, Japan has discovered that cysteinylated albumin (oxidized albumin) in serum can be used as an early diagnostic marker for diabetic kidney disease. Compared with urinary albumin, serum oxidized albumin not only reflects renal pathology at an earlier stage, but can also predict the progression of renal pathology by its degree of elevation. The researchers believe that it can be used as a new diagnostic marker for early diagnosis of diabetic kidney disease. Diabetic kidney disease is one of three major complications of diabetes. Its prognosis is difficult to improve as it progresses so diagnosing it as early as possible and providing appropriate therapeutic intervention ...

High-intensity intermittent training improves spatial memory in rats

2021-05-17
Tsukuba, Japan--Researchers at the University of Tsukuba found that, despite only covering about one-third of the distance in HIIT compared with that covered in endurance training, similar improvements in exercise capacity and brain function were observed for both forms of exercise. "We investigated how rats' muscles and brains--specifically, the region of the brain involved in spatial learning called the hippocampus--adapted to these types of exercise, and how the rats consequently learned and remembered navigating mazes," explains Professor Hideaki Soya, the principal investigator. In the experiment, rats were assigned to 1 of 3 groups--resting, endurance running, or alternating intervals ...

Cypriot grapes perform well in heat and on taste

Cypriot grapes perform well in heat and on taste
2021-05-17
Researchers at the University of Adelaide have found several grape varieties native to Cyprus, which tolerate drought conditions better than some international varieties popular in Australia, contain chemical compounds responsible for flavours preferred by Australian consumers. The study published in OENO One follows earlier research with Cypriot grape varieties Maratheftiko and Xynisteri in particular, which showed they are well adapted to a hot climate and continue to perform well as the climate becomes hotter. Lead author and PhD student Alexander Copper, from the University of ...

New combination immunotherapy plus ART expand innate cells critical to controlling HIV

2021-05-17
ATLANTA - Yerkes National Primate Research Center researchers in collaboration with Institut Pasteur have determined a combination immunotherapy of Interleukin-21 (IL-21) and interferon alpha (IFN?) when added to antiviral therapy (ART) is effective in generating highly functional natural killer (NK) cells that can help control and reduce simian immunodeficiency virus (SIV) in animal models. This finding, published online today in Nature Communications, is key for developing additional treatment options to control HIV/AIDS, which impacts 38 million people worldwide. ART is the current leading treatment for HIV/AIDS. It is capable of reducing the virus to undetectable levels, but is ...

Climate policies, transition risk, and financial stability

Climate policies, transition risk, and financial stability
2021-05-17
The way in which banks react to climate risks and uncertainty could impact financial stability as well as the world's transition to a low-carbon economy. A new study by researchers from IIASA and the Vienna University of Economics and Business explored the role that banks' expectations about climate-related risks will play in fostering or hindering an orderly low-carbon transition. According to the study published in a special issue on climate risks and financial stability of the Journal of Financial Stability, banks and their expectations about climate-related risks - and especially ...

LAST 30 PRESS RELEASES:

Young minds, big ideas: Florida’s first Invention Convention ignites innovation at USF

New study reveals how to make prescribed forest fires burn safer and cleaner

Inactive components in agricultural runoff may be hidden contributors to drinking water hazards

Colombia’s peatlands could be a crucial tool to fight climate change. But first we have to find them

Researchers refine a hybrid music therapy intervention for patients with cardiac and pulmonary conditions

Research Spotlight: Combining dexmedetomidine with spinal anesthesia prolongs pain relief and decreases shivering during surgery

Pennington Biomedical’s 2025 Bray Obesity Symposium to offer on-demand continuing education for physicians

Unlocking faster orthodontic treatments: the role of atf6 in bone remodeling

SwRI-led Lucy mission survey of main belt asteroid Donaldjohanson imminent

New bat cell lines and reagents help to study bat antiviral immune responses against hantaviruses and coronaviruses

Preterm birth might be predicted with high accuracy with new cheap, non-invasive test, based on cell-free DNA collected in standard early pregnancy testing

CVD researcher/clinician named editor-in-chief of Circulation: Genomic and Precision Medicine.

Holy shift: More Americans finding faith outside church

New analysis underscores health risks of e-cigarettes

USTC develops high-performance biomimetic proton gating system

Uncovering the molecular drivers of liver cancer

A bowling revolution: Modeling the perfect conditions for a strike

Simulate sound in 3D at a finer scale than humans can perceive

Screening history, stage at diagnosis, and mortality in screen-detected breast cancer

Pitt researchers release Phage images with unprecedented detail

Sound wave research for breast cancer receives $5.5 million

Gene variant linked to benign prostate hyperplasia risk in Lebanese men

Teoxane announces new study reinforcing the biocompatibility, safety and efficacy of RHA®4 in dynamic facial support

Study identifies U.S. hotspots for drinking water quality violations and lack of access to safe, clean water

Busted! Researchers revolutionize fraud detection with machine learning

Earthworm-inspired multimodal pneumatic continuous soft robot enhanced by winding transmission

Coastal heritage threatened by climate change

A tale of two hummingbird bills


Corn leads to improved performance in lithium-sulfur batteries

SynGAP Research Fund (SRF), dba Cure SYNGAP1, announces Board of Trustees Update 2025

[Press-News.org] Stair climbing offers significant cardiovascular and muscular benefits for heart patients