The properties of non-racemic dihydrofurans have been studied at Samara Polytech
This will make it possible to create bioactive compounds
2021-05-28
(Press-News.org) The research team of the Department of Organic Chemistry of Samara Polytech under the leadership of Doctor of Chemical Sciences, Head of the Department Yuri Klimochkin and Doctor of Chemical Sciences, Professor Alexander Reznikov in cooperation with the crystallographic research group of Lomonosov Moscow State University (supervisor - candidate of chemical sciences, senior researcher Victor Rybakov) completed a study to obtain non-racemic 4,5-dihydrofurans based on Michael addition and study their chemical properties. The announcement of a scientific article with the results of the latest research is posted on the cover of the authoritative journal Tetrahedron.
"Studying the method of obtaining non-racemic 4,5-dihydrofurans will make it possible to create biologically active compounds, and it is also possible that some of them are potential drugs against cancer, neurodegenerative diseases," Dmitry Nikerov, assistant of the Department of Organic Chemistry says.
An important advantage of the scientific developments of the team is the widespread use of cheap complexes of base metals such as nickel.
INFORMATION:
Scientists are investigating ways to obtain non-racemic heterocycles based on the methods of asymmetric metal complex catalysis with the financial support of the Russian Science Foundation (grant 18-13-00447).
For references:
Samara Polytech as a flagship university offers a wide range of education and research programs and aims at development and transfer of high-quality and practically-oriented knowledge. The university has an established reputation in technical developments and focuses on quality education, scientific and pragmatic research, combining theory and practice in the leading regional businesses and enterprises. Education is conducted in 30 integrated groups of specialties and areas of training (about 200 degree programs including bachelor, master programs and 55 PhD programs) such as oil and gas, chemistry and petrochemistry, mechanics and energy, transportation, food production, defense, IT, mechanical and automotive engineering, engineering systems administration and automation, material science and metallurgy, biotechnology, industrial ecology, architecture, civil engineering and design, etc.
The international research journal Tetrahedron is known all over the world for its rich history, as well as for the works of great chemists, whose contribution to the development of science is of great value. The journal is published by Elsevier in the Netherlands and is indexed in the Scopus and Web of Science databases. Tetrahedron publishes research of great importance in organic chemistry and related disciplines such as organic materials and bioorganic chemistry.
ELSE PRESS RELEASES FROM THIS DATE:
2021-05-28
CHAPEL HILL, NC - A new study published in Nature Communications demonstrates that a consortium of bacteria designed to complement missing or underrepresented functions in the imbalanced microbiome of inflammatory bowel disease (IBD) patients, prevented and treated chronic immune-mediated colitis in humanized mouse models. The study's senior author, Balfour Sartor, MD, Midget Distinguished Professor of Medicine, Microbiology and Immunology, Co-Director of the UNC Multidisciplinary IBD Center, said the results are encouraging for future use treating Crohn's disease and ulcerative colitis patients.
"The idea with this treatment is to restore the normal ...
2021-05-28
Dark Matter Particle Explorer (DAMPE) Collaboration directly observed a spectral softening of helium nuclei at about 34TeV for the first time. This work was based on measurements data of the helium spectrum with kinetic energies from 70 GeV to 80 TeV (17.5 GeV/n to 20 TeV/n for per nucleon) recorded by the DAMPE.
The relevant results were published in Physical Review Letters.
Galactic cosmic rays (GCRs) offers important ways to deeply understand the astrophysical particle origin and accelerators and the interstellar medium of the Galaxy. Helium nuclei, the second most abundant nuclear element of cosmic rays, is a distinguishing feature of space.
As for GCRs, the energy spectrum is supposed to follow a negative power law distribution when energies are below the "knee" (at ...
2021-05-28
By putting a piece of soft, strain-sensing sheet on the skin may be able to detect skin disorders non-invasively and in real-time very soon. A research team co-led by a scientist from City University of Hong Kong (CityU) has designed a simple electromechanical device that can be used for deep tissue pathology diagnosis, such as psoriasis, in an automated and non-invasive fashion. The findings will lay a foundation for future applications in the clinical evaluation of skin cancers and or dermatology diseases.
The research is co-led by Dr Yu Xinge, Assistant Professor from CityU's Department of Biomedical Engineering, and scientists from and Northwestern University in the US. Their findings have been published in the science journal Nature Biomedical Engineering, titled "Miniaturized ...
2021-05-28
New Haven, Conn. -- The ancient burrowers of the seafloor have been getting a bum rap for years.
These prehistoric dirt churners -- a wide assortment of worms, trilobites, and other animals that lived in Earth's oceans hundreds of millions of years ago -- are thought to have played a key role in creating the conditions needed for marine life to flourish. Their activities altered the chemical makeup of the sea itself and the amount of oxygen in the oceans, in a process called bioturbation.
But did that bioturbation help or hinder the expansion of complex animal life? A new Yale study, published in the journal Earth and Planetary Science Letters, found that ...
2021-05-28
New Haven, Conn. -- When San Francisco voters overwhelmingly approved a ballot measure banning the sale of flavored tobacco products in 2018, public health advocates celebrated. After all, tobacco use poses a significant threat to public health and health equity, and flavors are particularly attractive to youth.
But according to a new study from the Yale School of Public Health (YSPH), that law may have had the opposite effect. Analyses found that, after the ban's implementation, high school students' odds of smoking conventional cigarettes doubled in San Francisco's school district relative to trends in districts without the ban, even when adjusting for individual demographics and other ...
2021-05-28
This new 3D effect can be the foundation for topological quantum phenomena, which are believed to be particularly robust and therefore promising candidates for extremely powerful quantum technologies. These results have just been published in the scientific journal Nature Communications.
Dr. Tobias Meng and Dr. Johannes Gooth are early career researchers in the Würzburg-Dresdner Cluster of Excellence ct.qmat that researches topological quantum materials since 2019. They could hardly believe the findings of a recent publication in "Nature" claiming that electrons in the topological metal zirconium pentatelluride (ZrTe5) move only in two-dimensional ...
2021-05-28
WHAT:
An environment in which family members support one another and express their feelings can reduce the effects of social deprivation on cognitive ability and development among adopted children, suggests a small study by researchers at the National Institutes of Health. In contrast, rule-driven households where family members are in conflict may increase an adopted child's chances for cognitive, behavioral and emotional difficulties.
The study was conducted by Margaret F. Keil, Ph.D., and colleagues in the Section on Endocrinology and Genetics at NIH's Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). It appears in Pediatric Research.
Researchers enrolled children who had spent at least eight ...
2021-05-28
An analysis led by North Carolina State University researchers found counties with more socially vulnerable populations had a higher density of natural gas pipelines overall.
The findings suggest counties that are more socially vulnerable are also at greater risk of facing water and air pollution, public health and safety issues, and other negative impacts associated with the pipelines.
"We know that the network, as it stands today, is already distributed in such a way that any negative impacts fall disproportionately on vulnerable communities," ...
2021-05-28
Hormonal contraceptives, e.g. the pill, the patch, and the vaginal ring, contain synthetic hormones that prevent pregnancy by either stopping ovulation, changing the cervical mucus to stop sperm from passing through the cervix and finding an egg, or changing the womb's lining to prevent a fertilized egg from being implanted in it.
Despite their widespread use, hormonal contraceptives are known to increase the risk of breast cancer, which is the most common cause of cancer-related death among women worldwide, and also topped the list of most commonly diagnosed cancers in 2020.
The main component of hormonal contraceptives are progestins, ...
2021-05-28
Anesthesia may be an exact science, but it's not yet fully personalized. Anesthesiologists use a variety of methods to calculate the right dose for a given patient: clinical studies, medical databases and laboratory measurements, for example. However, every individual responds to anesthetics in a different way, and there's no way of knowing what that response will be until the anesthetic is administered.
Personalizing dosage
Today patients often receive supplemental doses of an anesthetic during their operation based on their reaction. The role of anesthesiologists is to make sure that a patient doesn't wake up too soon and has no memory of the procedure, but they must use ...
LAST 30 PRESS RELEASES:
[Press-News.org] The properties of non-racemic dihydrofurans have been studied at Samara Polytech
This will make it possible to create bioactive compounds
