(Press-News.org) Like amyloid plaque, the genetic variant APOE4 has long been associated with Alzheimer's disease, but still little is known about the role the gene plays in the disease process.
Now, a new study published in END
USC study reveals potential new treatment target for Alzheimer's disease
Researchers at Keck School of Medicine of USC identify a novel target related to the blood-brain barrier and a potential therapy that offers hope for slowing progression of Alzheimer's disease in people with the APOE4 gene
2021-06-14
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Neurons, nerve cells in the brain, are central players in brain function. However, a key role for glia, long considered support cells, is emerging. A research group at the University of Basel has now discovered two new types of glial cells in the brain, by unleashing adult stem cells from their quiescent state. These new types of glia may play an important role in brain plasticity and repair.
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What happens in brain cells affected by Alzheimer's disease?
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Moreover, they identified a correlation between the progression of the disease and certain corpuscles in the cell nuclei. They published their report in the journal Acta Neuropathological Communications on 13 April 2021.
Aggregates seem to have a function
Affecting over 50 million people, Alzheimer's disease is the most common form of dementia and primarily occurs in people over the age of 65. The pathology of the disease in the brain is mainly characterised by two factors: beta-amyloid plaques outside the nerve cells and tau proteins. The tau protein stabilises tube-like structures (microtubules) inside cells, which are relevant ...
Bionic reconstruction: New foot for 'Mia' the bearded vulture
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With Oskar Aszmann and his team at the Department of Plastic, Reconstructive and Aesthetic Surgery, MedUni Vienna has long been regarded as a world leader in bionic limb reconstruction. It was only last year that the world's first fully integrated bionic arm prosthesis was developed at MedUni Vienna. This is ready-to-use and is described as "Plug and Play". Although all bionic aids have so far been used in humans, the technique known as osseointegration (direct skeletal attachment) has now been used for the very first time in a bearded vulture - the creature was given a new foot. A paper on this ground-breaking procedure has been published today (Friday) in the prestigious Journal Scientific Reports.
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Novel magnet design with magic mirror-like properties
2021-06-14
Researchers at Tohoku University have demonstrated the designability of novel magnets with magic mirror-like characteristics in organic-inorganic hybrid perovskite (OIHP)-type compounds.
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Although the superior optical properties of OIHPs have been mainly studied for their photoelectric characteristics, several OIHP-type compounds are known to function as magnets that transmit light. Combining the excellent optical ...
The sun's clock
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Not only the very concise 11-year cycle, but also all other periodic solar activity fluctuations can be clocked by planetary attractive forces. This is the conclusion drawn by Dr. Frank Stefani and his colleagues from the Institute of Fluid Dynamics at the Helmholtz-Zentrum Dresden-Rossendorf (HZDR) and from the Institute of Continuous Media Mechanics in Perm, Russia. With new model calculations, they are proposing a comprehensive explanation of all important known sun cycles for the first time. They also reveal the longest fluctuations in activity over thousands of years as a chaotic process. ...
Earliest memories can start from the age of two-and-a-half, new study shows
2021-06-14
On average the earliest memories that people can recall point back to when they were just two-and-a-half years old, a new study suggests.
The findings, published in peer-reviewed journal Memory, pushes back the previous conclusions of the average age of earliest memories by a whole year.
They are presented in a new 21-year study, which followed on from a review of already-existing data.
"When one's earliest memory occurs, it is a moving target rather than being a single static memory," explains childhood amnesia expert and lead author Dr Carole Peterson, from Memorial University of Newfoundland.
"Thus, what many people provide when asked for their earliest memory is not a boundary or watershed beginning, before which there are no memories. Rather, ...
A quarter of global harvests at risk if agriculture does not adapt to climate change
2021-06-14
Shifts in weather patterns induced by climate change will increase extreme heat and reduce rainfall across major crop growing regions, with impacts on agricultural production. Will this trigger a decline in the supply of calories needed to sustain the world's growing population?
According to a study published in the Journal of Environmental Economics and Management, global calorie supplies are subject to continuing or even increasing vulnerability to climate change. Climate change could reduce global crop yields by 10% by mid-century and 25% by century's end, under a vigorous warming scenario, if farmers cannot adapt better than they did historically. ...
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[Press-News.org] USC study reveals potential new treatment target for Alzheimer's diseaseResearchers at Keck School of Medicine of USC identify a novel target related to the blood-brain barrier and a potential therapy that offers hope for slowing progression of Alzheimer's disease in people with the APOE4 gene