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USC study reveals potential new treatment target for Alzheimer's disease

Researchers at Keck School of Medicine of USC identify a novel target related to the blood-brain barrier and a potential therapy that offers hope for slowing progression of Alzheimer's disease in people with the APOE4 gene

USC study reveals potential new treatment target for Alzheimer's disease
2021-06-14
(Press-News.org) Like amyloid plaque, the genetic variant APOE4 has long been associated with Alzheimer's disease, but still little is known about the role the gene plays in the disease process.

Now, a new study published in END

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USC study reveals potential new treatment target for Alzheimer's disease

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Moreover, they identified a correlation between the progression of the disease and certain corpuscles in the cell nuclei. They published their report in the journal Acta Neuropathological Communications on 13 April 2021. Aggregates seem to have a function Affecting over 50 million people, Alzheimer's disease is the most common form of dementia and primarily occurs in people over the age of 65. The pathology of the disease in the brain is mainly characterised by two factors: beta-amyloid plaques outside the nerve cells and tau proteins. The tau protein stabilises tube-like structures (microtubules) inside cells, which are relevant ...

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[Press-News.org] USC study reveals potential new treatment target for Alzheimer's disease
Researchers at Keck School of Medicine of USC identify a novel target related to the blood-brain barrier and a potential therapy that offers hope for slowing progression of Alzheimer's disease in people with the APOE4 gene