PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

More seniors may have undiagnosed dementia than previously thought

2021-06-23
(Press-News.org) Only 1 in 10 older adults in a large national survey who were found to have cognitive impairment consistent with dementia reported a formal medical diagnosis of the condition.

Using data from the Health and Retirement Study to develop a nationally representative sample of roughly 6 million Americans age 65 or older, researchers at the University of Michigan, North Dakota State University and Ohio University found that 91% of people with cognitive impairment consistent with dementia told questioners they had a formal medical diagnosis of Alzheimer's disease or dementia.

"(The discrepancy) was higher than I was expecting," said Sheria Robinson-Lane, study co-author and assistant professor at the U-M School of Nursing.

When proxy reporters (generally, family members) responded, the prevalence dropped from 91% to around 75%, which is still very significant, she said. While many people may have been diagnosed and remain unaware or forgot about their diagnosis, what's concerning is that cognitive assessment, specifically dementia screening, isn't routine during annual well visits for older adults.

COVID-19 gives these numbers heightened significance because people with dementia have higher risk for hospitalization and death following an infection, Robinson-Lane said. COVID-19 also causes long-standing neurological effects in some people, perhaps increasing risk for future dementia-related diagnoses.

"Now more than ever, these routine screenings and assessments are really critical," she said. "I think it's particularly important to have some baseline information available to providers of patients over 65."

Co-author Ryan McGrath, an assistant professor at North Dakota State University, suggested that the migration to telemedicine during the COVID-19 pandemic further underscores the importance of cognitive assessments.

"We recommend that health care providers screen for low cognitive functioning during routine health assessments when possible," he said. "A telemedicine option may reduce clinic time and expand reach."

The prevalence of not having reported a dementia-related diagnosis, despite being identified as living with a cognitive impairment consistent with dementia, differed by gender, education and race.

People who identified as non-Hispanic Black had a higher estimated prevalence (93%) of no reported diagnosis, as did males (99.7%) compared to females (90.2%) The estimated prevalence of no reported diagnosis for non-high school graduates was about 93.5%, compared to 91% for those with at least a high school education.

"There is a large disparity in dementia-related treatment and diagnosis among Black older adults, who are often diagnosed much later in the disease trajectory compared to other racial and ethnic groups," Robinson-Lane said.

Education is often a proxy for socioeconomic status, so throughout life, wealthier individuals have more access to resources that affect both risk and disease progression, she said. And, evidence suggests that education may influence cognitive testing performance.

The Medicare visit is supposed to include a cognitive screening, but it can be difficult to ascertain a cognitive concern in a 20-minute annual visit, she said. Adding a specific cognitive assessment can also take up visit time.

Often, Robinson-Lane hears from concerned family members who don't know next steps, or the family member they're concerned about wants to maintain independence and privacy, and doctors can't share information without the patient's consent.

She encourages open communication and reminds families that they can still share information with the loved one's provider directly or through a nurse or medical assistant.

INFORMATION:

The study was published ahead of print and is scheduled to appear June 29 in the Journal of Alzheimer's Disease. Other authors of the study included: Bruno Giordiani of U-M, Brenda Vincent of North Dakota State, and Brian Clark and Julie Suhr of Ohio University.

Study abstract: Self-Reported Dementia-Related Diagnosis Underestimates the Prevalence of Older Americans Living with Possible Dementia



ELSE PRESS RELEASES FROM THIS DATE:

Flavored e-cigarettes may affect the brain differently than non-flavored

2021-06-23
Flavoring can change how the brain responds to e-cigarette aerosols that contain nicotine, according to Penn State College of Medicine researchers. Andrea Hobkirk and her team used functional magnetic resonance imaging (MRI) to understand how the brain's reward areas react to e-cigarette aerosol with and without flavor. "There are nearly 12 million e-cigarette users in the United States," Hobkirk, an assistant professor of psychiatry and behavioral health at Penn State College of Medicine, said. "The vast majority use e-cigarettes with menthol, mint, fruity and dessert-type flavors. Although regulations that limit the sale of flavored e-cigarettes may help curb use among youth, they might also stop adults from using e-cigarettes as a smoking ...

Study explores how readers at partisan news sites respond to challenging news events

2021-06-23
Researchers from Bentley University have been exploring how readers at partisan news sites respond to news events that challenge their worldview. In a forthcoming paper in the journal ACM Transactions on Social Computing, they report results of a study that examines reader comments on stories surrounding the 2017 Roy Moore Alabama senate race at two partisan news sites: a left-leaning news site (Daily Kos) and a right-leaning news site (Breitbart). They consider the alleged sexual misconduct of Mr. Moore as a challenging news event for the right-leaning readers; and the subsequent nomination of Mr. Moore as the Republican candidate as a challenging news event for the left-leaning readers. Their analysis identifies the obstacles that readers face as they try to make sense ...

Scientists obtain real-time look at how cancers evolve

2021-06-23
NEW YORK CITY, June 23, 2021 -- From amoebas to zebras, all living things evolve. They change over time as pressures from the environment cause individuals with certain traits to become more common in a population while those with other traits become less common. Cancer is no different. Within a growing tumor, cancer cells with the best ability to compete for resources and withstand environmental stressors will come to dominate in frequency. It's "survival of the fittest" on a microscopic scale. But fitness -- how well suited any particular individual is to its environment -- isn't set in stone; it can change when the environment changes. The cancer cells that might do best in an environment saturated ...

Flipping a molecular switch for heart fibrosis

Flipping a molecular switch for heart fibrosis
2021-06-23
SAN FRANCISCO, CA--June 23, 2021--A healthy heart is a pliable, ever-moving organ. But under stress--from injury, cardiovascular disease, or aging--the heart thickens and stiffens in a process known as fibrosis, which involves diffuse scar-like tissue. Slowing or stopping fibrosis to treat and prevent heart failure has long been a goal of cardiologists. Now, researchers at Gladstone Institutes have discovered a master switch for fibrosis in the heart. When the heart is under stress, they found, the gene MEOX1 is turned on in cells called fibroblasts, spurring fibrosis. Their new study, published in the journal Nature, suggests that blocking ...

Drug doubles down on bone cancer, metastasis

Drug doubles down on bone cancer, metastasis
2021-06-23
HOUSTON - (June 23, 2021) - Bone cancer is hard to treat and prone to metastasis. Research teams at Rice University and Baylor College of Medicine have a new strategy to attack it. Chemist Han Xiao at Rice and biologist Xiang Zhang at Baylor and their labs have developed an antibody conjugate called BonTarg that delivers drugs to bone tumors and inhibits metastasis. Their open-access study, which appears in Science Advances, shows how Xiao's pClick technology can be used to link bone-targeting antibodies and therapeutic molecules. In experiments, they used pClick to couple a molecule used to treat osteoporosis, alendronate, with the HER2-targeting antibody trastuzumab used to treat breast cancer and found it significantly enhanced the concentration ...

Cancer survivors' tongues less sensitive to tastes than those of healthy peers

Cancer survivors tongues less sensitive to tastes than those of healthy peers
2021-06-23
Most survivors of squamous cell head and neck cancers report that their sense of taste is dulled, changed or lost during radiation treatment, causing them to lose interest in eating and diminishing their quality of life. In a study of taste and smell dysfunction with 40 cancer survivors, scientists at the University of Illinois Urbana-Champaign found that the tips of these individuals' tongues were significantly less sensitive to bitter, salty or sweet tastes than peers in the control group who had never been diagnosed with cancer. In a paper published in the journal Chemical Senses, the U. of I. team said this diminished taste sensitivity suggested that the taste ...

Cold weather cost New England electric customers nearly $1.8 billion in one month; A new study suggests ways to mitigate fuel shortages

2021-06-23
In New England, constraints in the supply of natural gas have led to nearly a quarter of all unscheduled power plant outages. In a new study, researchers used data from power plant failures in the 2010s to develop a supply curve of the costs required for generators to mitigate fuel shortages in the region. The study found that storing both oil and gas on-site could reduce dependence by power plants on gas grids in geographic areas with few pipelines. The study was conducted by researchers at Carnegie Mellon University (CMU), The Pennsylvania State University, and the North American Electric Reliability Corporation. It is published in The Electricity Journal. "Gas ...

You can have too much of a good thing, says study financial analysts' work-life balance

You can have too much of a good thing, says study financial analysts work-life balance
2021-06-23
Toronto - Last winter, Goldman Sachs reported it was working to make things better after a group of junior analysts revolted against 100-hour work weeks. That's a smart thing to do, suggests a new study from the University of Toronto's Rotman School of Management. Drawing from more than 6,000 employee reviews of their workplaces and data on their firms' forecasting accuracy, the research shows that making improvements to hardworking analysts' work-life balance produces dividends for the company and for the analysts' careers. "There is a lot of anecdotal evidence, but here we provide large-scale evidence that supports the recent push to grant these employees at least some reprieve from the extremes of their jobs," said Ole-Kristian Hope, who is the Deloitte Professor of Accounting ...

GSA's journal's add seven articles on COVID-19 and aging

2021-06-23
The Gerontological Society of America's highly cited, peer-reviewed journals are continuing to publish scientific articles on COVID-19. The following were published between May 4 and June 14; all are free to access: Cardiometabolic therapy and mortality in very old patients with diabetes hospitalized due to COVID-19: Research article in The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences by Jose Manuel Ramos-Rincón, MD, PhD, Luis M. Pérez-Belmonte, MD, PhD, Francisco Javier Carrasco-Sánchez, MD, PhD, Sergio Jansen-Chaparro, MD, PhD, Mercedes De-Sousa-Baena, MD, José Bueno-Fonseca, MD, ...

Cat-borne parasite Toxoplasma induces fatally bold behavior in hyena cubs

Cat-borne parasite Toxoplasma induces fatally bold behavior in hyena cubs
2021-06-23
Best known for its presence in house cats and a tendency to infect and alter the behaviors of rodents and humans, the parasite Toxoplasma gondii (T. gondii) is also associated with bold behavior among wild hyena cubs and risk of death during interactions with lions, finds new research from the University of Colorado Boulder. The findings, published this week in Nature Communications, reinforce previous research which has found the parasite can prompt profound behavioral changes in its hosts, and potentially in the 2 billion people worldwide estimated to be infected by it. While T. gondii has been well studied in laboratory settings with humans and wild-caught ...

LAST 30 PRESS RELEASES:

Perfecting the view on a crystal’s imperfection

Fossil frogs share their skincare secrets

Existing drugs studied in patients with rare immune diseases

Loma Linda University study reveals alarming rates of pediatric injuries from mechanical bull riding

Excessive pregnancy weight gain and substantial postpartum weight retention common in military health care beneficiaries

Odor-causing bacteria in armpits targeted using bacteriophage-derived lysin

Women’s heart disease is underdiagnosed, but new machine learning models can help solve this problem

Extracting high-purity gold from electrical and electronic waste

Tropical fish are invading Australian ocean water

No bull: How creating less-gassy cows could help fight climate change

ECU researchers call for enhanced research into common post-stroke condition

SharpeRatio@k: novel metric for evaluation of risk-return tradeoff in off-policy evaluation

$1.8M NIH grant will help researchers follow a virus on its path to the nucleus

Follow-up 50 years on finds landmark steroid study remains safe

Active military service may heighten women’s risk of having low birthweight babies

Significant global variation in national COVID-19 treatment guidelines

Cost increasingly important motive for quitting smoking for 1 in 4 adults in England

Is there an association between HPV vaccination and anti-NMDA receptor encephalitis?

Blood-based multi-omics guided detection of a precancerous pancreatic tumor

Eye-opener: Pupils enlarge when people focus on tasks

Current Nanomaterials and Current Analytical Chemistry have been indexed in Ei Compendex

International balance of power determined by Chinese control over emerging technologies, study shows

New writing therapy helps late-stage cancer patients face biggest fears

National Jewish Health researchers identify connection between air pollutants and allergic diseases

In the United States, the election of progressive prosecutors led to higher relative rates of property and overall crime, but not to higher relative rates of violent crime

European Court of Human Rights is “backsliding” on legal protections for asylum seekers, study says

Being treated by a female physician associated with lower risk for death

Treatment from female doctors leads to lower mortality and hospital readmission rates

Historically redlined areas see more modern-day gun violence

Bonobos aren’t as peace-loving as we thought

[Press-News.org] More seniors may have undiagnosed dementia than previously thought