Outcomes for COVID-19 patients 1 year after loss of smell

What The Study Did: The incidence of Bell palsy among patients with COVID-19 was compared with individuals vaccinated against the disease. Authors: Akina Tamaki, M.D., of the University Hospitals Cleveland Medical Center, is the corresponding author.  To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamaoto.2021.1266) Editor's Note: The article includes conflicts of interest disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support. INFORMATION: Media advisory: ...

An updated analysis of American COVID-19 deaths throughout 2020 reveals an even bigger drop in average life expectancy as well as still-substantial disparities by race and ethnicity. Lead author Theresa Andrasfay, a postdoctoral scholar at the USC Leonard Davis School of Gerontology, and coauthor Noreen Goldman of Princeton University first examined the pandemic's effect on American life expectancy in October 2020. Their initial study, published in Proceedings of the National Academy of Sciences in January 2021, showed the largest single-year decline in life expectancy in at least 40 years and the lowest life expectancy estimated since 2003. The updated analysis, which included the more than 380,000 US COVID-19 deaths in 2020 and used 2018 life expectancies as a comparison, ...

When cancers metastasize, cells from the primary tumor break away, travel through the blood or lymph system, and form new tumors in other body parts. Although metastasis are responsible for more than 90% of all cancer deaths, limited progress has been made in treating cancers that have spread. Besides DNA, RNA is the other molecule of life. For several years now, RNA has become just as important as DNA in understanding the book of life. Especially, messenger RNA (mRNA), the basis of the Covid-19 vaccines, has been put in the spotlight. Just as with DNA, in addition to the 4 well known letters (A, U, G, C), there are further letters defining the RNA alphabet or ...

Discovering and engineering nanobodies with properties suitable for treating human diseases ranging from cancer to COVID-19 is a time-consuming, laborious process. To that end, University of Michigan researchers found a simple method for identifying nanobodies with drug-like properties suitable for preventing SARS-CoV-2 infections. They demonstrated the approach by generating nanobodies that neutralized the SARS-CoV-2 virus more potently than an antibody isolated from an infected patient and a nanobody isolated from an immunized animal. Nanobodies are small antibody fragments ...

Many people don't realize that the trillions of bacteria, viruses, and fungi residing within the gastrointestinal tract--collectively called the gut microbiome-- are connected to overall health, and specifically to cancer. Manipulating the gut microbiome to produce "beneficial" commensal microbes, which protect the host from pathogens and can boost immune responses, among other things, could potentially help patients respond better to cancer drugs called immune checkpoint inhibitors, a type of immunotherapy. To that end, researchers at the University of Michigan have developed ...

Migrating storms and local weather systems known as cyclones and anticyclones were thought to contribute to behaviors and properties of our global weather system. However, the means to probe cyclones and anticyclones were limited. For the first time, researchers demonstrated a new three-dimensional analytical methodology that can quantify the way individual cyclones and anticyclones impact broader weather systems. This study aids longer-term circulation and climate studies, including how storm characteristics may change in the future. To many people, the term cyclone probably conjures up images of ferocious storm ...

A study published on 21 May in Child Development shows that the early production of beat gestures with the hands (i.e., gestures normally associated with emphasis that do not represent the semantic content of speech) by infants between 14 and 58 months of age in natural interactions with their carers predicts that in their later development, nearing the age of five, these children obtain better results insofar as their oral narrative skills. The authors analysed the predictive value of beat gestures, compared with flip gestures of the hands and iconic gestures However, the study did ...

Scientists of Tomsk Polytechnic University jointly with colleagues from Spanish universities have offered a simple method how to enhance the responsivity of terahertz radiation detectors by 3.5 folds using a small Teflon cube. The 1 mm cube must be put on the surface of the detector without changing the inner design of the detector. Such detectors are applied, for instance, in a full-body scanner, spectrometer, in medical devices for diagnosing skin cancer, burn injuries, pathological changes in blood. The research findings are published in the Optics Letters academic journal (IF: 3,714; Q1). Terahertz range lies between ...

Coastal bays are momentous transition zones connecting terrestrial and marine ecosystems. Xiangshan Bay is a typically eutrophic and semi-enclosed bay in the East China Sea. A recent study took Xiangshan Bay as an example, revealing the sources and transformation of dissolved organic matter (DOM) in this eutrophic bay. Dissolved organic matter (DOM), consisting of a vast of complex compounds, has received much attention due to its significant contribution to the largest reduced organic carbon pool in the ocean, which is sizable to the atmosphere CO2 reservoir. Coastal bays are known as semi-enclosed signature and long water retention ...

Monocultures dominate arable land today, with vast areas given over to single elite varieties that promise a high yield. But planting arable land with just one type of crop has its disadvantages: these areas are easy game for fungal and insect pests, posing a threat to crops. To keep pests at bay, farmers are having to use resistant varieties and various pesticides. Mixed cultures present a potential alternative to monocultures. Rather than having large expanses of land planted with just one species or variety, several species or varieties are sown alongside each other. However, as little research has been done ...