Changes in opioid prescribing to children, teens, young adults

What The Study Did: Researchers compared health care access and quality scores for the United States with high-income countries with universal health insurance coverage and compared scores among U.S. states with varying insurance coverage. Authors: Marcia R. Weaver, Ph.D., of the University of Washington in Seattle, is the corresponding author. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2021.14730) Editor's Note: The article includes conflict of interest and funding/support disclosures. Please see the article for additional information, including other ...

What The Study Did: High school students in Austria were surveyed about their well-being, sleep quality, eating and symptoms of depression and anxiety during the COVID-19 pandemic. Authors: Christoph Pieh, M.D., of Danube University in Krems, Austria, is the corresponding author. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2021.14866) Editor's Note: The article includes conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support. INFORMATION: Media advisory: The full study ...

A gene variant that lowers white blood cell levels and is common in individuals with African ancestry contributes to unnecessary bone marrow biopsies, according to a study published June 28 in JAMA Internal Medicine. The findings from three institutions, led by investigators at Vanderbilt University Medical Center, provide an example of how using genetic data could reduce a health disparity. "We've essentially created this racial health disparity by not fully considering how genetic variation affects white blood cell levels," said Jonathan Mosley, MD, PhD, assistant professor of Medicine and Biomedical Informatics at VUMC. "Our study supports genotyping African Americans before ...

Most people associate the term "wearable" with a fitness tracker, smartwatch, or wireless earbuds. But what if you could wear cutting-edge biotechnology in your clothing, and it could warn you when you were exposed to something dangerous? A team of researchers from the Wyss Institute for Biologically Inspired Engineering at Harvard University and the Massachusetts Institute of Technology has found a way to embed synthetic biology reactions into fabrics, creating wearable biosensors that can be customized to detect pathogens and toxins and alert the wearer. The team has integrated this technology into standard face masks to detect the presence of the SARS-CoV-2 virus in a patient's breath. The button-activated mask ...

Researchers at Northwestern and George Washington (GW) universities have developed the first-ever transient pacemaker -- a wireless, battery-free, fully implantable pacing device that disappears after it's no longer needed. The thin, flexible, lightweight device could be used in patients who need temporary pacing after cardiac surgery or while waiting for a permanent pacemaker. All components of the pacemaker are biocompatible and naturally absorb into the body's biofluids over the course of five to seven weeks, without needing surgical extraction. The device wirelessly harvests energy from an external, remote antenna using near-field ...

A worldwide team led by UC Santa Barbara scientists at Las Cumbres Observatory has discovered the first convincing evidence for a new type of stellar explosion -- an electron-capture supernova. While they have been theorized for 40 years, real-world examples have been elusive. They are thought to arise from the explosions of massive super-asymptotic giant branch (SAGB) stars, for which there has also been scant evidence. The discovery, published in Nature Astronomy, also sheds new light on the thousand-year mystery of the supernova from A.D. 1054 that was visible all over the world in the daytime, before eventually becoming the Crab Nebula. Historically, supernovae have ...

A worldwide team led by scientists at Las Cumbres Observatory has discovered the first convincing evidence for a new type of stellar explosion -- an electron-capture supernova. While they have been theorized for 40 years, real-world examples have been elusive. They are thought to arise from the explosions of massive super-asymptotic giant branch (SAGB) stars, for which there has also been scant evidence. The discovery also sheds new light on the thousand-year mystery of the supernova from A.D. 1054 that was seen all over the world in the daytime, before eventually becoming the Crab Nebula. Historically, there have been two main supernova types. One is a thermonuclear supernova -- the explosion of a white dwarf star after it gains matter in a binary star system. These white ...

Engineers at MIT and Harvard University have designed a novel face mask that can diagnose the wearer with Covid-19 within about 90 minutes. The masks are embedded with tiny, disposable sensors that can be fitted into other face masks and could also be adapted to detect other viruses. The sensors are based on freeze-dried cellular machinery that the research team has previously developed for use in paper diagnostics for viruses such as Ebola and Zika. In a new study, the researchers showed that the sensors could be incorporated into not only face masks but also clothing such as lab coats, potentially offering a new way to ...

All life on Earth 500 million years ago lived in the oceans, but scientists know little about how these animals and algae developed. A newly discovered fossil deposit near Kunming, China, may hold the keys to understanding how these organisms laid the foundations for life on land and at sea today, according to an international team of researchers. The fossil deposit, called the Haiyan Lagerstätte, contains an exceptionally preserved trove of early vertebrates and other rare, soft-bodied organisms, more than 50% of which are in the larval and juvenile stages of development. Dating to the Cambrian geologic period approximately 518 million years ago and providing researchers with ...

The world of microbes living in the human gut can have far-reaching effects on human health. Multiple diseases, including inflammatory bowel disease (IBD), are tied to the balance of these microbes, suggesting that restoring the right balance could help treat disease. Many probiotics -- living yeasts or bacteria -- that are currently on the market have been optimized through evolution in the context of a healthy gut. However, in order to treat complex diseases such as IBD, a probiotic would need to serve many functions, including an ability to turn off inflammation, reverse damage and restore the gut microbiome. Given all of these needs, researchers from Brigham and Women's Hospital have developed a "designer" ...