Poor and minority communities suffer more from extreme heat in US cities

As a minimally invasive method for cancer therapy at precise locations, NIR-induced photothermal therapy (PTT) has drawn extensively attention. The therapeutic mechanism is the use of photothermal agents (PTAs) in the treatment of tumors,and its therapeutic effect happens only at the tumor site where both light-absorbent and localized laser radiation coexist. The development of PTAs with NIR-II absorbance, ranging from 1000nm to 1700 nm, can efficiently improve their penetrating ability and therapeutic effects because of their high penetration depth in the body. Howerever, several disadvantages are associated with these NIR-II responsive PTAs for their ...

Over the past years, graphene oxide membranes have been mainly studied for water desalination and dye separation. However, membranes have a wide range of applications such as the food industry. A research group led by Aaron Morelos-Gomez of Shinshu University's Global Aqua Innovation Center investigated the application of graphene oxide membranes for milk which typically creates dense foulant layers on polymeric membranes. Graphene oxide membranes have the advantage to create a porous foulant layer, therefore, their filtration performance can be maintained better than commercial polymeric membranes. The unique chemical and ...

Clinician well-being is imperative to providing high-quality patient care, yet clinician burnout continues to increase, especially over the last year due to the COVID-19 pandemic. Four leading cardiovascular organizations - the American College of Cardiology, the American Heart Association, the European Society of Cardiology and the World Heart Federation - are calling for global action to improve clinician well-being in a joint opinion paper published today. "Over the last several decades, there have been significant changes in health care with the expansion of technology, regulatory burden and clerical task loads. These developments have come at a cost to the ...

A new population-based study looking at nearly 30 years of billing data demonstrates that sex-based differences in Ontario Health Insurance Plan (OHIP) payments exists for Canadian ophthalmologists. A team led by researchers and clinicians from the Donald K. Johnson Eye Institute, part of the Krembil Research Institute at University Health Network (UHN), studied 22,389 Ontario physicians across three decades and found a significant payment gap between female and male ophthalmologists even after accounting for age, and some practice differences. This disparity was more pronounced among ophthalmologists when compared to other surgical, medical procedural and medical non-procedural specialty groups. "This is real and robust ...

DALLAS, July 13, 2021 -- Sharing the results of genetic testing for cardiomyopathy in adolescents ages 13-18 does not appear to cause emotional harm to families or adversely impact family function or dynamics, according to new research published today in Circulation: Genomic and Precision Medicine, an American Heart Association journal. Genetic testing for cardiomyopathy in symptomatic children has the potential to confirm a diagnosis, clarify prognosis, determine eligibility for disease-specific cardiomyopathy therapies and even inform risk for other family members. Genetic testing for asymptomatic adults and children also occurs after one of their family members receives positive cardiomyopathy genetic ...

Philadelphia, July 13, 2021--Adding to the growing body of literature demonstrating the feasibility of correcting lethal genetic diseases before birth, researchers at Children's Hospital of Philadelphia (CHOP) have used DNA base editing in a prenatal mouse model to correct a lysosomal storage disease known as Hurler syndrome. Using an adenine base editor delivered in an adeno-associated viral vector, the researchers corrected the single base mutation responsible for the condition, which begins before birth and affects multiple organs, with the potential to cause death in childhood if untreated. The findings were published ...

Hair dye, perfume, jewellery. Beautifying to most, but for some they are equivalent to rashes, irritation and reduced quality of life. Together with hay fever and food allergies, allergic contact dermatitis due to exposure to e.g. nickel and perfume ingredients represents the majority of allergic reactions seen among Danes. Traditionally, researchers have distinguished between immediate and delayed allergic reactions, depending on which parts of the immune system that is responsible for the reaction. E.g., hay fever and food allergies are 'immediate' forms that cause immediate symptoms, whereas it can take days before the skin reacts to things like nickel and perfume. But now a new study ...

A new paper in The Economic Journal, published by by Oxford University Press, indicates that the presence of adult entertainment establishments may decrease sex crimes, significantly. The role of entertainment establishments (strip clubs, escort services, adult bookstores, and adult movie theaters) in communities is controversial. Citizens often view them as centers of vice. While some have suggested that these clubs and services may improve behavior if people use them instead of committing sex crimes, such establishments may reinforce the view of women as objects, leading to more violence against them. This paper exploits a unique data set of high frequency precinct level crime information from New York City, due to its controversial stop-and-frisk policing policy. The researchers ...

BINGHAMTON, N.Y. -- New research from Binghamton University, State University of New York suggests that the demographic collapse at the core of the Easter Island myth didn't really happen. You probably know this story, or a version of it: On Easter Island, the people cut down every tree, perhaps to make fields for agriculture or to erect giant statues to honor their clans. This foolish decision led to a catastrophic collapse, with only a few thousand remaining to witness the first European boats landing on their remote shores in 1722. But did the demographic collapse at the core of the Easter Island myth really happen? The answer, according to new research by Binghamton ...

Combining chemotherapy and BRAF oncogene inhibitors is a very effective strategy for fighting metastatic melanoma, the leading cause of death from skin cancer in the world. This has been demonstrated in a study by researchers from the Hospital del Mar Medical Research Institute (IMIM), Hospital del Mar, and CIBER Cancer (CIBERONC), in collaboration with the Bellvitge Medical Research Institute (ICO-IDIBELL), which has just been published in the journal Oncogene. The study, which involved the IMIM's Stem Cells and Cancer Research Group and doctors from the Dermatology and Pathology Departments at Hospital del Mar, analysed what effect ...