Examining association between cycling, risk of death among people with diabetes

What The Study Did: The experiences, perspectives and needs of transgender young people in accessing health care are described in this review of 91 studies. Authors: Lauren S. H. Chong, M.D., of the Children's Hospital at Westmead in Sydney, Australia, is the corresponding author. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamapediatrics.2021.2061) Editor's Note: The article includes conflict of interest disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support. #  ...

What The Study Did: These results suggest that substantial proportions of Latinx immigrants have immigration concerns about engaging in COVID-19-related testing, treatment and contact tracing. Authors: Carol L. Galletly, J.D., Ph.D., Medical College of Wisconsin in Milwaukee, is the corresponding author. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2021.17049) Editor's Note: The article includes conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support. #  #  ...

What The Study Did: The association between daily coffee consumption and the risk of cardiac arrhythmias was evaluated in this study. Authors: Gregory M. Marcus, M.D., M.A.S., of the University of California, San Francisco, is the corresponding author. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamainternmed.2021.3616) Editor's Note: The article includes conflicts of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support. #  #  # Media advisory: The full study and commentary are ...

What The Study Did: This study included a meta-analysis that combined the results of 74 studies with 2.7 million participants to estimate how common globally dementia is in people younger than age 65. Authors: Sebastian Köhler, Ph.D., of Maastricht University in Maastricht, the Netherlands, is the corresponding author. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamaneurol.2021.2161) Editor's Note: The article includes conflicts of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and ...

What The Study Did: Researchers examined racial/ethnic disparities in outpatient visit rates to 29 physician specialties in the United States. Authors: Christopher Cai, M.D., of the Internal Medicine Residency Program at Brigham and Women's Hospital/Harvard Medical School in Boston, is the corresponding author. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamainternmed.2021.3771) Editor's Note: The article includes conflicts of interest disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support. INFORMATION: Media advisory: The full study is linked to this news release. Embed ...

An international team anchored by the Event Horizon Telescope (EHT) Collaboration, which is known for capturing the first image of a black hole in the galaxy Messier 87, has now imaged the heart of the nearby radio galaxy Centaurus A in unprecedented detail. The astronomers pinpoint the location of the central supermassive black hole and reveal how a gigantic jet is being born. Most remarkably, only the outer edges of the jet seem to emit radiation, which challenges our theoretical models of jets. This work, led by Michael Janssen from the Max Planck Institute for Radio Astronomy ...

LA JOLLA--Fighting a tumor is a marathon, not a sprint. For cancer-fighting T cells, the race is sometimes just too long, and the T cells quit fighting. Researchers even have a name for this phenomenon: T cell exhaustion. In a new Nature Immunology study, researchers at La Jolla Institute for Immunology (LJI) report that T cells can be engineered to clear tumors without succumbing to T cell exhaustion. "The idea is to give the cells a little bit of armor against the exhaustion program," says LJI Professor Patrick Hogan, Ph.D. "The cells can go into the tumor to do their job, ...

BOSTON - Lymph nodes are critical to the body's immune response against tumors but paradoxically, cancer cells that spread, or metastasize, to lymph nodes can often avoid being eliminated by immune cells. Recent experiments by investigators at Massachusetts General Hospital (MGH) and Boston University School of Medicine provide insights on the details behind this immune evasion, which could help scientists develop strategies to overcome it. The findings are published in Nature Biomedical Engineering. "We know that lymph nodes are often the first place cancer ...

A new USC study of a common, yet poorly understood type of white blood cell reveals the immune cell's response to pathogens differs greatly by sex and by age. In this mouse study, males proved much more susceptible to a condition called sepsis than females. However, the scientists also found that the female disease-defense system is hardly perfect; their system changes with age to become nearly as harmful as the males'. Those are the key findings in a study that appears today in Nature Aging. The study has important implications for studying disease and cures, especially for sepsis, a condition in which the body's defense ...

WHAT: A new study published in JAMA Neurology suggests that certain features that appear on CT scans help predict outcomes following mild traumatic brain injury (TBI). Patterns detected on the scans may help guide follow up treatment as well as improve recruitment and research study design for head injury clinical trials. Researchers led by Geoffrey Manley, M.D., Ph.D., professor of neurological surgery at the University of California San Francisco, conducted CT scans in 1,935 subjects with mild TBI and followed their outcomes up to 12 months after injury. This research was part of the Transforming Research and Clinical Knowledge in Traumatic Brain Injury (TRACK-TBI) study, a large research effort funded by the National Institutes of ...