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New findings published in AJIC highlight clinician perspectives on barriers to reliable hand hygiene

First study to report differences across specific clinician subgroups offers insights to improve practices through human factors engineering

( Arlington, Va., March 16, 2023 – Findings from a new study published in the American Journal of Infection Control (AJIC), highlight perceptions of and barriers to reliable hand hygiene among specific clinician subgroups. The results, from the first study of its kind, provide insights that can be used to design and implement future, targeted interventions to optimize hand hygiene reliability among medical professionals.

“While prior studies focused on challenges to hand hygiene reliability by healthcare role, we believe our study is the first to highlight key differences in perceived barriers and facilitators by service line and career tenure,” said Ana M. Vaughan-Malloy, MD, MPH, Associate Hospital Epidemiologist, Boston Children’s Hospital, and the lead author on the published study. “Our data demonstrate that nuances across clinician subgroups can impact an organization’s efforts to optimize hand hygiene reliability through the healthcare continuum and can inform human factors engineering tools and methods to help organizations more effectively promote hand hygiene.”

While hand hygiene is critical to prevent healthcare-associated infections (HAIs), reliability remains low in hospitals today and there is a lack of published data evaluating clinicians’ perceived barriers to achieving and maintaining high hand hygiene reliability.

Dr. Vaughan and colleagues evaluated the potential of human factors engineering (HFE) to identify interventions that could be implemented across physician groups to improve hand hygiene reliability. HFE applies information about human factors to design interactive systems that involve people, tools, technology, and work environments, to ensure safety, effectiveness, and ease of use. Awareness of barriers, facilitators, and perceptions is required for HFE tools and methods to be utilized effectively.

Using one of the most commonly applied HFE models (the Systems Engineering Initiative for Patient Safety 2.0 model, or SEIPS 2.0), as well as two World Health Organization hand hygiene surveys, the researchers developed an electronic survey exploring six HFE domains: technology and tools, person, organization, tasks, environment, and care processes. They shared the survey with 200 physicians, nurse practitioners, and physician assistants practicing within a 406-bed pediatric hospital.

Results suggest that a majority of clinicians view hand hygiene as essential to patient safety, but aspects of organizational culture, environment, tasks, and tools are barriers to high reliability. Additionally, the researchers identified interesting differences in perceived facilitators and barriers to high reliability in hand hygiene between clinicians in surgery/anesthesia vs. medical specialties.

Specifically, among 61 respondents (75% physicians, 18% nurse practitioners, and 7% physician assistants), key findings include:

97% believed personal hand hygiene is effective in preventing HAIs and, overall, respondents assigned a relatively low level of effort required to perform good HH when caring for patients (median 2 on a Likert scale of 0-10). However, 28% of respondents reported using gloves as a substitute for hand hygiene, and 12% felt hand hygiene education for healthcare workers is not an effective means of improving reliability. 87% reported alcohol-based hand rub (ABHR) availability as very effective in improving reliability, however 77% reported dispensers were “sometimes” or “often” empty. 27% reported that ABHR is irritating to the skin. Clinicians in surgery/anesthesia were more likely than those in other medical specialties to note skin irritation from ABHR (OR 4.94) and less likely to believe feedback was effective in improving hand hygiene (OR 0.26). 25% of respondents indicated the layout of patient care areas was not conducive to performing hand hygiene. 15% reported that staffing shortages and 11% said the pace and demands of work precluded hand hygiene. Compared with their later career counterparts, early career clinicians were more likely to report feedback from both colleagues (OR 4.20) and patients (OR 4.20) as effective in improving hand hygiene reliability. “Improving and maintaining hand hygiene compliance has been a long-standing and seemingly intractable challenge in healthcare,” said Patricia Jackson, RN, MA, CIC, FAPIC, 2023 APIC president. “This study highlights opportunities to improve hand hygiene reliability through effective application of human factors engineering tools and methods.”


About APIC

Founded in 1972, the Association for Professionals in Infection Control and Epidemiology (APIC) is the leading association for infection preventionists and epidemiologists. With more than 15,000 members, APIC advances the science and practice of infection prevention and control. APIC carries out its mission through research, advocacy, and patient safety; education, credentialing, and certification; and fostering development of the infection prevention and control workforce of the future. Together with our members and partners, we are working toward a safer world through the prevention of infection. Join us and learn more at

About AJIC

As the official peer-reviewed journal of APIC, The American Journal of Infection Control (AJIC) is the foremost resource on infection control, epidemiology, infectious diseases, quality management, occupational health, and disease prevention. Published by Elsevier, AJIC also publishes infection control guidelines from APIC and the CDC. AJIC is included in Index Medicus and CINAHL. Visit AJIC at


“Using a Human Factors Framework to Assess Clinician Perceptions of and Barriers to High Reliability in Hand Hygiene,” by Ana M. Vaughan-Malloy, MD, MPH; Jenny Chan Yuen, MSPH; and Thomas J. Sandora, MD, MPH, was published online in AJIC on March 16, 2023. The article may be found at:



Ana M. Vaughan-Malloy, MD, MPH (corresponding author:, Boston Children’s Hospital, Boston, Mass., USA

Jenny Chan Yuen, MSPH, Boston Children’s Hospital, Boston, Mass., USA

Thomas J. Sandora, MD, MPH, Boston Children’s Hospital, Boston, Mass., USA


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[] New findings published in AJIC highlight clinician perspectives on barriers to reliable hand hygiene
First study to report differences across specific clinician subgroups offers insights to improve practices through human factors engineering