PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Where there’s smoke, there’s thiocyanate: McMaster researchers find tobacco users in Canada are exposed to higher levels of cyanide than other regions

Where there’s smoke, there’s thiocyanate: McMaster researchers find tobacco users in Canada are exposed to higher levels of cyanide than other regions
2023-03-24
(Press-News.org) HAMILTON, ON – Mar 24, 2024 – Tobacco users in Canada are exposed to higher levels of cyanide than smokers in lower-income nations, according to a large-scale population health study from McMaster University.

Scientists made the discovery while investigating the molecule thiocyanate – a detoxified metabolite excreted by the body after cyanide inhalation. It was measured as a urinary biomarker of tobacco use in a study of self-reported smokers and non-smokers from 14 countries of varying socioeconomic status.

“We expected the urinary thiocyanate levels would be similar across regions and reflect primarily smoking intensity. However, we noticed significant elevation of thiocyanate in smokers from high-income countries even after adjusting for differences in the number of cigarettes smoked per day,” says Philip Britz-McKibbin, co-author of the study and a professor of chemistry and chemical biology at McMaster.

Tobacco-related illness remains the leading cause of preventable illness and premature death in Canada, contributing to approximately 48,000 deaths annually. According to researchers, the findings could be caused by the type of cigarettes smoked in high-income countries like Canada.

“The cigarettes commonly consumed in Canada are highly engineered products with lower tar and nicotine content to imply they’re less harmful. Heavy smokers with nicotine dependence compensate by smoking more aggressively with more frequent and deeper inhalations that may elicit more harm, such as greater exposure to the respiratory and cardiotoxin, cyanide.”

Smoking rates in Canada have declined from 26 per cent in 2001 to 13 per cent in 2020. But participation in smoking cessation programs has declined during the COVID-19 pandemic, leading to concern about a potential uptick in smoking rates, including cannabis use and a plethora of vaping of products popular among young adults.

Researchers say urinary thiocyanate can serve as a robust biomarker of the harms of tobacco smoke that will aid future research on the global tobacco picture, since most smokers now reside in developing countries. As smoking rates have decreased here in Canada, at-risk groups like youth and pregnant women have been prone to underreport their tobacco use when surveyed, making a reliable biomarker more valuable.

“Historically assessing tobacco behaviors have relied on questionnaires that are prone to bias, especially when comparing different countries and local cultures. The idea is to find robust methods that can quantify recent tobacco smoke exposure more reliably and objectively, which may better predict disease risk and prioritize interventions for smoking cessation.” says Britz-Mckibbin.

The study was published in the latest issue of Nicotine and Tobacco Research and received funding from the Natural Sciences and Engineering Research Council of Canada, Genome Canada, the Canada Foundation for Innovation, Hamilton Health Sciences New Investigator Fund, and an internal grant from the Population Health Research Institute.

 

-30-

 

For more information please contact:

Matt Innes-Leroux

Media Relations

McMaster University

647-921-5461 (c)

leroum2@mcmaster.ca

 

Photos of Philip Britz-McKibbin can be found here

Credit: McMaster University

END


[Attachments] See images for this press release:
Where there’s smoke, there’s thiocyanate: McMaster researchers find tobacco users in Canada are exposed to higher levels of cyanide than other regions Where there’s smoke, there’s thiocyanate: McMaster researchers find tobacco users in Canada are exposed to higher levels of cyanide than other regions 2 Where there’s smoke, there’s thiocyanate: McMaster researchers find tobacco users in Canada are exposed to higher levels of cyanide than other regions 3

ELSE PRESS RELEASES FROM THIS DATE:

SIAM Conference on Applications of Dynamical Systems (DS23)

2023-03-24
The application of dynamical systems theory to areas outside of mathematics continues to be a vibrant, exciting, and fruitful endeavor. These application areas are diverse and multidisciplinary, covering areas that include biology, chemistry, physics, climate science, social science, industrial mathematics, data science, and more. This conference strives to amass a blend of application-oriented material and the mathematics that informs and supports the discipline. The goals of the conference are a cross-fertilization of ideas from different application areas and increased communication between ...

SIAM Conference on Mathematical & Computational Issues in the Geosciences (GS23)

2023-03-24
The study of geophysical systems at all scales, whether from a scientific or technological perspective, calls for sophisticated mathematical modeling, efficient computational methods, and pervasive integration with data. This effort is fundamentally interdisciplinary. This conference aims to stimulate the exchange of ideas among geoscientific modelers, applied mathematicians, statisticians, and other scientists, fostering new research in the mathematical foundations with an impact on geoscience applications. END ...

New experiment translates quantum information between technologies in an important step for the quantum internet

New experiment translates quantum information between technologies in an important step for the quantum internet
2023-03-24
Researchers have discovered a way to “translate” quantum information between different kinds of quantum technologies, with significant implications for quantum computing, communication, and networking. The research, published in the journal Nature on Wednesday, was funded by the Army Research Office (ARO), the Air Force Office of Scientific Research (AFOSR), and the NSF Quantum Leap Challenge Institute for Hybrid Quantum Architectures and Networks (HQAN), which is led by the University of Illinois Urbana-Champaign. It represents a new way to convert quantum information from the format used by quantum computers to the format needed ...

NASA prepares for historic asteroid sample delivery on Sept. 24

NASA prepares for historic asteroid sample delivery on Sept. 24
2023-03-24
NASA's OSIRIS-REx spacecraft is cruising back to Earth with a sample it collected from the rocky surface of asteroid Bennu. When its sample capsule parachutes down into the Utah desert on Sept. 24, OSIRIS-REx will become the United States’ first-ever mission to return an asteroid sample to Earth.   After seven years in space, including a nail-biting touchdown on Bennu to gather dust and rocks, this intrepid mission is about to face one of its biggest challenges yet: deliver the asteroid sample to Earth while protecting it from heat, vibrations, and earthly contaminants.     “Once the sample capsule touches down, our team ...

11 ways to improve airlines for customers

11 ways to improve airlines for customers
2023-03-24
COLUMBIA, Mo— The name of the game is customer satisfaction, especially in the airline industry where companies are constantly jockeying for business by promising better service than their competitors. Now a professor at the University of Missouri has used artificial intelligence to sort through thousands of customer reviews and identify where airlines are falling short. Sharan Srinivas, an assistant professor with a joint appointment in the Department of Industrial and Systems Engineering and the Department of Marketing, used AI to analyze nearly 400,000 unique, ...

New mining technology uses CO2 as tool to access critical minerals

2023-03-24
A mining technology pioneered by researchers at the Bureau of Economic Geology at The University of Texas at Austin could reduce the amount of energy needed to access critical minerals vital for modern energy technologies and capture greenhouse gases along the way. Transitioning the world’s energy to technologies and sources with low-carbon emissions will take, in part, tremendous amounts of lithium, nickel, cobalt and other critical minerals that exist in low concentrations in the Earth’s crust. Mining those elements takes much energy and produces waste, which can negatively affect the environment and create significant amounts of greenhouse ...

Wastewater to energy: new treatment process can improve biorefinery sustainability

Wastewater to energy: new treatment process can improve biorefinery sustainability
2023-03-24
Wastewater from biorefineries that convert plants into fuel is full of organic materials that cannot be efficiently treated with conventional wastewater systems, making it costly and energy-intensive to manage. However, those rich organic materials are an untapped source of chemical energy that can be recovered as valuable products, including biogas, a clean-burning renewable fuel. A study by researchers at the Department of Energy’s Center for Advanced Bioenergy and Bioproducts Innovation (CABBI) found that recovering resources from wastewater can substantially improve the economic and environmental sustainability of second-generation ...

U.S. Department of Energy and Stellantis announce the Battery Workforce Challenge

U.S. Department of Energy and Stellantis announce the Battery Workforce Challenge
2023-03-24
The U.S. Department of Energy (DOE) and Stellantis today announced the launch of the Battery Workforce Challenge, which includes a three-year collegiate engineering competition; vocational training; youth education in science, technology, engineering and math (STEM); and career and technical education.   DOE has set a bold target to address the climate crisis and puts our nation on a path to achieve net-zero emissions, economy-wide, by 2050 for the benefit of all Americans. Key to this target goal are the design and development of advanced batteries to electrify ...

Study finds higher risk of sleep problems in gay, lesbian, and bisexual youth

2023-03-24
Toronto, ON - A new national study, published in LGBT Health, finds that lesbian, gay, and bisexual (LGB) youth are twice as likely to report trouble falling or staying asleep than their straight peers. Greater depression, stress, and family conflict contribute to the sleep problems of LGB youth. “Young people who identify as lesbian, gay, or bisexual may face discrimination and negative attitudes because of their sexual orientation. These experiences can make it harder for them to get a good night’s sleep,” says lead author, Jason Nagata, MD, assistant professor of pediatrics at the University of California, San Francisco. “Difficulties getting ...

UW researchers identify cell type that could be key to preventing marrow transplant complication

2023-03-24
A bone marrow transplant can be a lifesaving treatment for people with relapsed blood cancers, but a potentially lethal complication known as graft-versus-host disease put limitations on this procedure. New research from the University of Wisconsin–Madison is helping to change that by identifying the cell population that causes GVHD, a target that may make bone marrow transplants safer and more effective. An allogenic (from a donor) bone marrow transplant is a common treatment for blood cancers and other diseases of the immune system. During the transplant, the patient’s immune cells are replaced with the donor’s ...

LAST 30 PRESS RELEASES:

Korea University study identifies age 70 as cutoff for chemotherapy benefit in colorectal cancer

Study explores brain cell communication called ‘crosstalk’

4 beer and wine discoveries

Massage Therapy Foundation awards $299,465 research grant to Children’s Hospital of Philadelphia

Chung-Ang University develops chloride-resistant Ru nanocatalysts for sustainable hydrogen production from seawater

Afghanistan’s August 2025 earthquake reveals the cost of international isolation, UN scientists warn

Shortlist announced for Panmure House Prize

Small nuclear RNA base editing a safer alternative to CRISPR, UC San Diego researchers find

Can Hayabusa2 touchdown? New study reveals space mission’s target asteroid is tinier and faster than thought

Millisecond windows of time may be key to how we hear, study finds

Graz University of Technology opens up new avenues in lung cancer research with digital cell twin

Exoplanets are not water worlds

Study shows increasing ‘healthy competition’ between menu options nudges patients towards greener, lower-fat hospital food choices

New insights into melanoma plasticity uncover a critical role of iron metabolism

A graphene sandwich — deposited or transferred?

New light-powered motor fits inside a strand of hair

Oil rig study reveals vital role of tiny hoverflies

Children’s Hospital of Philadelphia researchers boost widespread use of dental varnish across pediatric network

iRECODE: A new computational method that brings clarity to single-cell analysis

New NUS-MOH study: Singapore’s healthcare sector carbon emissions 18% lower than expected, a milestone in the city-state’s net zero journey

QUT scientists create material to turn waste heat into clean power

Major new report sets out how to tackle the ‘profound and lasting impact’ of COVID-19 on cardiovascular health

Cosmic crime scene: White dwarf found devouring Pluto-like icy world

Major report tackles Covid’s cardiovascular crisis head-on

A third of licensed GPs in England not working in NHS general practice

ChatGPT “thought on the fly” when put through Ancient Greek maths puzzle

Engineers uncover why tiny particles form clusters in turbulent air

GLP-1RA drugs dramatically reduce death and cardiovascular risk in psoriasis patients

Psoriasis linked to increased risk of vision-threatening eye disease, study finds

Reprogramming obesity: New drug from Italian biotech aims to treat the underlying causes of obesity

[Press-News.org] Where there’s smoke, there’s thiocyanate: McMaster researchers find tobacco users in Canada are exposed to higher levels of cyanide than other regions