(Press-News.org) A new study by Cedars-Sinai investigators describes how ChatGPT, an artificial intelligence (AI) chatbot, may help improve health outcomes for patients with cirrhosis and liver cancer by providing easy-to-understand information about basic knowledge, lifestyle and treatments for these conditions.
The findings, published in the peer-reviewed journal Clinical and Molecular Hepatology, highlights the AI system’s potential to play a role in clinical practice.
“Patients with cirrhosis and/or liver cancer and their caregivers often have unmet needs and insufficient knowledge about managing and preventing complications of their disease,” said Brennan Spiegel, MD, MSHS, director of Health Services Research at Cedars-Sinai and co-corresponding author of the study. “We found ChatGPT—while it has limitations—can help empower patients and improve health literacy for different populations.”
Patients diagnosed with liver cancer and cirrhosis, an end-stage liver disease that is also a major risk factor for the most common form of liver cancer, often require extensive treatment that can be complex and challenging to manage.
“The complexity of the care required for this patient population makes patient empowerment with knowledge about their disease crucial for optimal outcomes,” said Alexander Kuo, MD, medical director of Liver Transplantation Medicine at Cedars-Sinai and co-corresponding author of the study. “While there are currently online resources for patients and caregivers, the literature available is often lengthy and difficult for many to understand, highlighting the limited options for this group.”
Personalized education AI models could help increase patient knowledge and education, noted Kuo.
One of those is ChatGPT, which stands for generative pre-trained transformer. It has quickly become popular for its human-like text in chatbot conversations where users can input any prompt and it will generate a response based on the information stored in its database.
It has already shown some potential for medical professionals by writing basic medical reports and correctly answering medical student examination questions.
“ChatGPT has shown to be able to provide professional, yet highly comprehensible responses,” said Yee Hui Yeo, MD, first author of the study and a clinical fellow in the Karsh Division of Gastroenterology and Hepatology at Cedars-Sinai. “However, this is one of the first studies to examine the ability of ChatGPT to answer clinically oriented, disease-specific questions correctly and compare its performance to physicians and trainees.”
To verify the accuracy of the AI model in its knowledge about both cirrhosis and liver cancer, investigators presented ChatGPT with 164 frequently asked questions in five categories. The ChatGPT answers were then graded independently by two liver transplant specialists.
Each question was posed twice to ChatGPT and was categorized as either basic knowledge, diagnosis, treatment, lifestyle or preventive medicine.
Study results include:
ChatGPT answered about 77% of the questions correctly, providing high levels of accuracy in 91 questions from a variety of categories.
The specialists grading the responses said 75% of the responses for basic knowledge, treatment and lifestyle were comprehensive or correct, but inadequate.
The proportion of responses that were “mixed with correct and incorrect data” was 22% for basic knowledge, 33% for diagnosis, 25% for treatment, 18% for lifestyle and 50% for preventive medicine.
The AI model also provided practical and useful advice to patients and caregivers regarding the next steps adjusting to a new diagnosis.
Still, the study left no doubt that advice from a physician was superior.
“While the model was able to demonstrate strong capability in the basic knowledge, lifestyle and treatment domains, it suffered on the ability to provide tailored recommendations according to the region where the inquirer lived,” said Yeo. “This is most likely due to the varied recommendations in liver cancer surveillance interval and indications reported by different professional societies. But we are hopeful that it will be more accurate in addressing the questions according to the inquirers’ location.”
“More research is still needed to better examine the tool in patient education, but we believe ChatGPT to be a very useful adjunctive tool for physicians—not a replacement—but adjunctive tool that provides access to reliable and accurate health information that is easy for many to understand,” Spiegel said. “We hope that this can help physicians to empower patients and improve health literacy for patients facing challenging conditions such as cirrhosis and liver cancer.”
Other Cedars-Sinai authors are Jamil Samaan, Hirsh Trivedi, Aarshi Vipani, Walid Ayoub, Ju Dong Yang and Omer Liran.
Study: ChatGPT has potential to help cirrhosis, liver cancer patients
The artificial intelligence system can serve as additional information tool for patients and physicians to help advance health outcomes
ELSE PRESS RELEASES FROM THIS DATE:
A healthy microbiome may prevent deadly infections in critically ill people
Twenty to 50 per cent of all critically ill patients contract potentially deadly infections during their stay in the intensive care unit or in hospital after being in the ICU – markedly increasing the risk of death. “Despite the use of antibiotics, hospital-acquired infections are a major clinical problem that persists to be a huge issue for which we don’t have good solutions,” says Dr. Braedon McDonald, MD, PhD, an intensive care physician at the Foothills Medical Centre (FMC) and assistant professor at the ...
Academic institutions receive lower financial returns from biotechnology licenses than commercial firms
BENTLEY UNIVERSITY The financial terms of biotechnology licenses from academic institutions are significantly less favorable than those of comparable licenses between commercial firms according to a new study from Bentley University’s Center for Integration of Science and Industry. The study, published in the journal PLOS ONE, shows that the royalties and payments to academic institutions are significantly lower than those to commercial firms for similar licenses and products at the same stages of development. The article, titled “Comparing the economic terms of biotechnology licenses from academic institutions with those ...
Harnessing nature to promote planetary sustainability
As Earth’s population grows, the demands of modern lifestyles place mounting strain on the global environment. Proposed solutions to preserve and promote planetary sustainability can sometimes prove more harmful than helpful. However, technologies that harness natural processes could be more successful. Such technologies are the focus of the latest issue of the open access journal PLOS Biology, which features a special collection publishing March 31st of papers highlighting biology-based solutions that could be applied to reduce carbon dioxide emissions, eliminate non-degradable plastics, produce food or energy ...
Study examines how social rank affects response to stress
Can an individual’s social status have an impact on their level of stress? Researchers at Tulane University put that question to the test and believe that social rank, particularly in females, does indeed affect the stress response. In a study published in Current Biology, Tulane psychology professor Jonathan Fadok, PhD, and postdoctoral researcher Lydia Smith-Osborne looked at two forms of psychosocial stress — social isolation and social instability — and how they manifest themselves based on social rank. They conducted their research on adult female mice, putting them in pairs and allowing them to form a stable ...
The stars in the brain may be information regulators
Long thought of as “brain glue,” the star-shaped cells called astrocytes—members of a family of cells found in the central nervous system called glial that help regulate blood flow, synaptic activity, keep neurons healthy, and play an important role in breathing. Despite this growing appreciation for astrocytes, much remains unknown about the role these cells play in helping neurons and the brain process information. “We believe astrocytes can add a new dimension to our understanding of how external and internal information is merged in the ...
The Institut Pasteur and the University of São Paulo sign articles of association to establish the Institut Pasteur in São Paulo
On Friday March 31st, 2023 at a ceremony in Paris, the Institut Pasteur President, Professor Stewart Cole, and the University of São Paulo (USP) Rector, Carlos Gilberto Carlotti Junior, signed articles of association for the Institut Pasteur in São Paulo, a private non-profit organization under Brazilian law. The mission of the institute, an associate member of the Pasteur Network, is to conduct research in the field of biology that contributes to the development of human health, and to promote outreach, education, innovation and knowledge transfer activities and public health measures. The Institut Pasteur ...
Mathematical model provides bolt of understanding for lightning-produced X-rays
UNIVERSITY PARK, Pa. — In the early 2000s, scientists observed lightning discharge producing X-rays comprising high energy photons — the same type used for medical imaging. Researchers could recreate this phenomenon in the lab, but they could not fully explain how and why lightning produced X-rays. Now, two decades later, a Penn State-led team has discovered a new physical mechanism explaining naturally occurring X-rays associated with lightning activity in the Earth’s atmosphere. They published their ...
nTIDE March 2023 Deeper Dive: Intersection of race and disability perpetuate inequalities in employment impacting Black/African American people with disabilities
East Hanover, NJ – March 31, 2023 – Since the pandemic, gains in the labor market have been slower to materialize for black/African American people with disabilities compared to their white counterparts, according to experts speaking last Friday during the nTIDE Deeper Dive Lunch & Learn Webinar. They discussed potential factors underlying why the disability employment gap is wider among members of the black/African American population when compared to the white population and how to integrate measures to effect change. Using data from the U.S. Bureau of Labor Statistics (BLS) for persons ages 16-64, the monthly employment-to-population ratio averaged ...
Researchers uncover the first steps driving antibiotic resistance
Antibiotic resistance is a global health threat. In 2019 alone, an estimated 1.3 million deaths were attributed to antibiotic resistant bacterial infections worldwide. Looking to contribute a solution to this growing problem, researchers at Baylor College of Medicine have been studying the process that drives antibiotic resistance at the molecular level. They report in the journal Molecular Cell crucial and surprising first steps that promote resistance to ciprofloxacin, or cipro for short, one of the most commonly prescribed antibiotics. The findings point at potential ...
Study reveals new insights into body salt handling
HUNTINGTON, W.Va. – A new study led by Marshall University researchers focuses on a novel mechanism of the body’s regulation of salt balance. The kidney plays a central role in the body’s ability to maintain an appropriate sodium balance, which is critical for the determination of blood pressure. Disorders of sodium balance contribute to the development and progression of many common diseases, including hypertension, heart disease and stroke. Na/K-ATPase (NKA) is the enzymatic machinery that drives absorption of sodium along the renal proximal tubule. As ...
LAST 30 PRESS RELEASES:
Drug limits dangerous reactions to allergy-triggering foods, Stanford Medicine-led study of kids finds
Measuring the properties of light: Scientists realise new method for determining quantum states
For faster access to gene and cell therapies in Europe
Scientists deliver portable total chemical analysis without pumps and tubes
A very long, winding road: Developing novel therapeutics for metastatic tumors
Unlocking health: How In Our DNA SC is pioneering genetic screening for South Carolinians
Down Under Demo: ONR touts additive manufacturing tech at Australian event
Study shows benralizumab is effective as a treatment for eosinophilic granulomatosis with polyangiitis, a rare form of vasculitis
Researchers identify new choice of therapy for rare autoimmune disease EGPA
NJIT marketing experts measure brain waves and skin current to predict emotions
Babies use immune system differently, but efficiently
Cloud clustering causes more extreme rain
Mindfulness at work protects against stress and burnout
Scientists closer to solving mysteries of universe after measuring gravity in quantum world
Revolutionary brain stimulation technique shows promise for treating brain disorders
Global warming increases the diversity of active soil bacteria
Patient mindset training helps care teams
Dual-energy harvesting device could power future wireless medical implants
Study: ‘Hexaplex’ vaccine aims to boost flu protection
New structural insights could lead to mechanical enhancement in alloys
New research challenges conventional picture of Parkinson's disease
Dairy cows fed botanicals-supplemented diets use energy more efficiently
Aston University receives nearly half a million pounds to create safer and greener batteries
New study shows glycan sugar coating of IgG immunoglobulin can predict cardiovascular health
Sir Peter Rigby appointed as honorary chair of Aston University’s new Digital Futures Institute
Yale School of Medicine receives a $575,000 grant from PolyBio Research Foundation to fund long COVID research
Common plant could help reduce food insecurity, researchers find
Innovative chemotherapy approach shows promise against lung cancer
Encoding computers of the future[Press-News.org] Study: ChatGPT has potential to help cirrhosis, liver cancer patients
The artificial intelligence system can serve as additional information tool for patients and physicians to help advance health outcomes