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BMI alone may not be a sufficient indicator of metabolic health

2023-06-15
(Press-News.org) CHICAGO—Body mass index (BMI) is not a complete measure of metabolic health, and a high proportion of U.S. adults with normal BMI still have obesity, according to research being presented Friday at ENDO 2023, the Endocrine Society’s annual meeting in Chicago, Ill.

The latest research highlights the importance of including what percentage of the body is fat, muscle, bone, and water, and how much fat is in the abdomen vs. the thighs to fully understand drivers for cardio-metabolic disease.

“We show that there are racial/ethnic differences in body fat, BMI, and body fat distribution which may provide evidence for future studies to further determine if these differences are possible drivers of the racial disparities seen in cardio-metabolic diseases,” said Aayush Visaria, M.D., M.P.H., an internal medicine resident at the Rutgers Robert Wood Johnson Medical School in New Brunswick, N.J.

Visaria and colleagues identified non-pregnant U.S. adults aged 20-59 years from the 2011-2018 National Health and Nutrition Examination Survey (NHANES) with whole body DEXA scan data. Their BMI was categorized by ethnicity (non-Asian: underweight<18.5, normal=18.5-24.9, overweight=25-29.9, obese≥30 kg/m2, Asian: <18.5, 18.5-22.9, 23-27.4, 27.5+).

The researchers estimated odds of obesity among adults as normal/overweight based on BMI or total body fat percentage (BF%) as ≥25% in male and ≥32% in female, by race (non-Hispanic White [NHW], non-Hispanic Black [NHB], Asian, Hispanic, and other). They also estimated mean DEXA adiposity measures by race.

They found that nearly 36% had BMI≥30 (the traditional definition of obesity) but 74% had obesity per BF%. Among normal BMI adults, 44% of non-Hispanic Whites, 27% of NHB, 49% of Hispanic, and 49% of Asians had obesity as per BF%. Among normal BMI adults, the mean android-to-gynoid fat ratio was 0.84 for NHW, 0.85 for NHB, 0.89 for Hispanics, and 0.91 for Asians.

Nearly 3 in 4 young-to-middle-aged U.S. adults were considered to have obesity according to BF% from DEXA scans. Asian Americans and Hispanics with seemingly normal BMI were more likely to have obesity, and more likely to have a greater proportion of abdominal fat than non-Hispanic Whites. Non-Hispanic Blacks had significantly lower chances of obesity at normal/overweight BMI ranges, and a lower proportion of abdominal fat.

“We hope this research will add to the idea of weight-inclusive care and allow clinicians to 1) routinely use supplementary measures of body fat such as waist circumference or bioimpedance-based body fat measurements (e.g. smart scales) in addition to BMI, 2) engage in practices to prevent unconscious biases that may occur when caring for a patient with obese BMI, and 3) engage in clinical decision-making that is not solely dependent on a BMI calculation but rather an overall idea of body composition and body fat distribution,” Visaria said.

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Endocrinologists are at the core of solving the most pressing health problems of our time, from diabetes and obesity to infertility, bone health, and hormone-related cancers. The Endocrine Society is the world’s oldest and largest organization of scientists devoted to hormone research and physicians who care for people with hormone-related conditions.

The Society has more than 18,000 members, including scientists, physicians, educators, nurses and students in 122 countries. To learn more about the Society and the field of endocrinology, visit our site at www.endocrine.org. Follow us on Twitter at @TheEndoSociety and @EndoMedia.

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[Press-News.org] BMI alone may not be a sufficient indicator of metabolic health