PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Buprenorphine dose and time to discontinuation among patients with opioid use disorder in the era of fentanyl

JAMA Network Open

2023-09-18
(Press-News.org) About The Study: The results of this study of 6,499 patients initiating buprenorphine treatment between 2016 and 2020 suggest that the value of higher buprenorphine doses than currently recommended needs to be considered for improving retention in treatment. 

Authors: Laura C. Chambers, Ph.D., M.P.H., of Brown University in Providence, Rhode Island, is the corresponding author. 

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ 

(doi:10.1001/jamanetworkopen.2023.34540)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2023.34540?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=091823

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

END


ELSE PRESS RELEASES FROM THIS DATE:

Telecare cuts costs, boosts quality of life for dementia patients

2023-09-18
A UCSF telecare program that improves outcomes for patients with dementia and lightens the load for unpaid caregivers also has the surprising bonus of cutting Medicare costs, according to UC San Francisco research. In the study, publishing in JAMA Internal Medicine on Sept. 18, 2023, researchers, led by UCSF, compared the Medicare costs of 780 patients with dementia. The patients were randomized 2:1 to receive Care Ecosystem support – which included medical and practical assistance – or their usual care for a 12-month period. Both groups were similar in age, severity of dementia ...

Higher buprenorphine doses associated with improved retention in treatment for opioid use disorder

2023-09-18
Individuals with opioid use disorder who were prescribed a lower buprenorphine dose were 20% more likely to discontinue treatment than those on a higher dose, according to a study of patients prescribed buprenorphine in Rhode Island from 2016 to 2020, as fentanyl became widely available. The study, published today in JAMA Network Open, was supported by the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health, and conducted by researchers at Brown University, Providence, Rhode Island; NIDA and the Rhode Island ...

Tracking down the formation of cardenolides in plants

Tracking down the formation of cardenolides in plants
2023-09-18
Plants produce an impressive array of metabolites, including many medically valuable steroids. Well-known examples of this class of substances obtained from plants are cardenolides. As early as 1785, the British physician William Withering (1741-1799) published a book on the red foxglove and its use in medicine (An account of the foxglove, and some of its medical uses: with practical remarks on dropsy, and other diseases. Birmingham 1785).  He had found out in experiments that taking extracts ...

The surprising origin of a deadly hospital infection

2023-09-18
Hospital staff spend a significant amount of time working to protect patients from acquiring infections while they are being cared for in the hospital. They employ various methods from hand hygiene to isolation rooms to rigorous environmental sanitation. Despite these efforts, hospital-onset infections still occur—the most common of which is caused by the bacterium Clostridioides difficile, or C. diff, the culprit of almost half a million infections in the U.S. each year. Surprising findings from a new study in Nature Medicine suggest that the burden of C. diff infection may be less a matter of hospital transmission and more a result of characteristics associated ...

Mature sperm lack intact mitochondrial DNA, study finds

2023-09-18
New research provides insight about the bedrock scientific principle that mitochondrial DNA — the distinct genetic code embedded in the organelle that serves as the powerplant of every cell in the body — is exclusively passed down by the mother. The study, a collaboration among Oregon Health & Science University and other institutions, published today in the journal Nature Genetics. Scientists have long recognized the fact that mitochondrial DNA, or mtDNA, comes exclusively from egg cells in humans, meaning only the mother contributes the genetic code carried by ...

Research identifies new potential hurdle for nano-based therapies

Research identifies new potential hurdle for nano-based therapies
2023-09-18
HOUSTON ― Researchers at The University of Texas MD Anderson Cancer Center have discovered that certain nano-based cancer therapies may be less effective in younger patients, highlighting the need for further investigation into the impact of aging on the body’s ability to respond to treatment. The researchers found age-related differences are due to how effectively the liver filters the bloodstream. Younger livers are more efficient at this process, which helps limit toxins in the blood but also filters out beneficial treatments, potentially rendering them ineffective. The study, published today in ...

Improving the properties of sweeteners for enhanced thermal energy storage

Improving the properties of sweeteners for enhanced thermal energy storage
2023-09-18
As we seek more efficient utilization of waste thermal energy, use of “phase change materials (PCMs)” is a good option. PCMs have a large latent heat capacity and the ability to store-and-release heat as they change from one state of matter to another. Among many PCMs, sugar alcohols (SAs), a class of organic compounds commonly used as sweeteners, stand out due to their low cost, non-toxic, non-corrosive, and biodegradable nature. In particular, SAs generally have their melting point in 100–200 °C, which is an important temperature range where a huge amount of waste heat exists but is currently ...

Ohio State leads new global climate center on AI for biodiversity change

2023-09-18
COLUMBUS, Ohio – The Ohio State University will lead a new multimillion dollar international center devoted to using artificial intelligence to help understand climate impacts on biodiversity.   The AI and Biodiversity Change (ABC) Global Climate Center will bring together ecologists and computer scientists from six universities in the United States and Canada, with partners in UK, Europe, and Australia, to develop new AI-enabled, data-supported approaches to study how changes in climate are impacting life – including animals, plants and insects – on Earth.   $5 ...

Ohio State researchers publish national guidelines for ALS genetic testing, counseling

2023-09-18
COLUMBUS, Ohio – Researchers at The Ohio State University Wexner Medical Center and College of Medicine led the creation of evidence-based consensus guidelines for genetic testing and counseling for patients with  amyotrophic lateral sclerosis (ALS), a neurodegenerative disease that affects the cells in the brain and spine. These evidence-based, consensus guidelines provide clinicians with a framework for the offer of genetic testing and outline the information that should be provided to persons with ALS before and after testing. In addition, the guidelines provide specific recommendations regarding ...

Study: Admissions policies that consider grades and test scores in context of available opportunities are linked to college success

2023-09-18
Indicators of high school grades and standardized test scores that take into account the levels of school, neighborhood, and family resources available to students are strongly associated with those students’ success in college, according to new research published today. The study, published in AERA Open, a peer-reviewed journal of the American Educational Research Association, emerges against the backdrop of the recent Supreme Court decision to ban race-conscious admissions in higher ...

LAST 30 PRESS RELEASES:

Terahertz pulses induce chirality in a non-chiral crystal

AI judged to be more compassionate than expert crisis responders: Study

Scale-up fabrication of perovskite quantum dots

Adverse childhood experiences influence potentially dangerous firearm-related behavior in adulthood

Bacteria found to eat forever chemicals — and even some of their toxic byproducts

London cabbies’ planning strategies could help inform future of AI

More acidic oceans may affect the sex of oysters

Transportation insecurity in Detroit and beyond

New tool enables phylogenomic analyses of entire genomes

Uncovering the role of Y chromosome genes in male fertility in mice

A single gene underlies male mating morphs in ruff sandpipers

Presenting CASTER – a novel method for evolutionary research

Reforestation boosts biodiversity, while other land-based climate mitigation strategies fall short

Seasonal vertical migrations limit role of krill in deep-ocean carbon storage

Child mortality has risen since pandemic, new study shows

Super enzyme that regulates testosterone levels in males discovered in ‘crazy’ bird species

Study tracks physical and cognitive impairments associated with long COVID

Novel model advances microfiber-reinforced concrete research

Scientists develop new AI method to forecast cyclone rapid intensification

Interpreting metamaterials from an artistic view

Smoking cannabis in the home increases odds of detectable levels in children

Ohio State astronomy professor awarded Henry Draper Medal

Communities of color face greater barriers in accessing opioid medications for pain management

Researchers track sharp increase in diagnoses for sedative, hypnotic and anxiety use disorder in young adults

Advancement in DNA quantum computing using electric field gradients and nuclear spins

How pomalidomide boosts the immune system to fight multiple myeloma

PREPSOIL webinar explores soil literacy among youth: Why it matters and how educators can foster it

Imagining the physics of George R.R. Martin’s fictional universe

New twist in mystery of dinosaurs' origin

Baseline fasting glucose level, age, sex, and BMI and the development of diabetes in US adults

[Press-News.org] Buprenorphine dose and time to discontinuation among patients with opioid use disorder in the era of fentanyl
JAMA Network Open