PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Buprenorphine dose and time to discontinuation among patients with opioid use disorder in the era of fentanyl

JAMA Network Open

2023-09-18
(Press-News.org) About The Study: The results of this study of 6,499 patients initiating buprenorphine treatment between 2016 and 2020 suggest that the value of higher buprenorphine doses than currently recommended needs to be considered for improving retention in treatment. 

Authors: Laura C. Chambers, Ph.D., M.P.H., of Brown University in Providence, Rhode Island, is the corresponding author. 

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ 

(doi:10.1001/jamanetworkopen.2023.34540)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2023.34540?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=091823

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

END


ELSE PRESS RELEASES FROM THIS DATE:

Telecare cuts costs, boosts quality of life for dementia patients

2023-09-18
A UCSF telecare program that improves outcomes for patients with dementia and lightens the load for unpaid caregivers also has the surprising bonus of cutting Medicare costs, according to UC San Francisco research. In the study, publishing in JAMA Internal Medicine on Sept. 18, 2023, researchers, led by UCSF, compared the Medicare costs of 780 patients with dementia. The patients were randomized 2:1 to receive Care Ecosystem support – which included medical and practical assistance – or their usual care for a 12-month period. Both groups were similar in age, severity of dementia ...

Higher buprenorphine doses associated with improved retention in treatment for opioid use disorder

2023-09-18
Individuals with opioid use disorder who were prescribed a lower buprenorphine dose were 20% more likely to discontinue treatment than those on a higher dose, according to a study of patients prescribed buprenorphine in Rhode Island from 2016 to 2020, as fentanyl became widely available. The study, published today in JAMA Network Open, was supported by the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health, and conducted by researchers at Brown University, Providence, Rhode Island; NIDA and the Rhode Island ...

Tracking down the formation of cardenolides in plants

Tracking down the formation of cardenolides in plants
2023-09-18
Plants produce an impressive array of metabolites, including many medically valuable steroids. Well-known examples of this class of substances obtained from plants are cardenolides. As early as 1785, the British physician William Withering (1741-1799) published a book on the red foxglove and its use in medicine (An account of the foxglove, and some of its medical uses: with practical remarks on dropsy, and other diseases. Birmingham 1785).  He had found out in experiments that taking extracts ...

The surprising origin of a deadly hospital infection

2023-09-18
Hospital staff spend a significant amount of time working to protect patients from acquiring infections while they are being cared for in the hospital. They employ various methods from hand hygiene to isolation rooms to rigorous environmental sanitation. Despite these efforts, hospital-onset infections still occur—the most common of which is caused by the bacterium Clostridioides difficile, or C. diff, the culprit of almost half a million infections in the U.S. each year. Surprising findings from a new study in Nature Medicine suggest that the burden of C. diff infection may be less a matter of hospital transmission and more a result of characteristics associated ...

Mature sperm lack intact mitochondrial DNA, study finds

2023-09-18
New research provides insight about the bedrock scientific principle that mitochondrial DNA — the distinct genetic code embedded in the organelle that serves as the powerplant of every cell in the body — is exclusively passed down by the mother. The study, a collaboration among Oregon Health & Science University and other institutions, published today in the journal Nature Genetics. Scientists have long recognized the fact that mitochondrial DNA, or mtDNA, comes exclusively from egg cells in humans, meaning only the mother contributes the genetic code carried by ...

Research identifies new potential hurdle for nano-based therapies

Research identifies new potential hurdle for nano-based therapies
2023-09-18
HOUSTON ― Researchers at The University of Texas MD Anderson Cancer Center have discovered that certain nano-based cancer therapies may be less effective in younger patients, highlighting the need for further investigation into the impact of aging on the body’s ability to respond to treatment. The researchers found age-related differences are due to how effectively the liver filters the bloodstream. Younger livers are more efficient at this process, which helps limit toxins in the blood but also filters out beneficial treatments, potentially rendering them ineffective. The study, published today in ...

Improving the properties of sweeteners for enhanced thermal energy storage

Improving the properties of sweeteners for enhanced thermal energy storage
2023-09-18
As we seek more efficient utilization of waste thermal energy, use of “phase change materials (PCMs)” is a good option. PCMs have a large latent heat capacity and the ability to store-and-release heat as they change from one state of matter to another. Among many PCMs, sugar alcohols (SAs), a class of organic compounds commonly used as sweeteners, stand out due to their low cost, non-toxic, non-corrosive, and biodegradable nature. In particular, SAs generally have their melting point in 100–200 °C, which is an important temperature range where a huge amount of waste heat exists but is currently ...

Ohio State leads new global climate center on AI for biodiversity change

2023-09-18
COLUMBUS, Ohio – The Ohio State University will lead a new multimillion dollar international center devoted to using artificial intelligence to help understand climate impacts on biodiversity.   The AI and Biodiversity Change (ABC) Global Climate Center will bring together ecologists and computer scientists from six universities in the United States and Canada, with partners in UK, Europe, and Australia, to develop new AI-enabled, data-supported approaches to study how changes in climate are impacting life – including animals, plants and insects – on Earth.   $5 ...

Ohio State researchers publish national guidelines for ALS genetic testing, counseling

2023-09-18
COLUMBUS, Ohio – Researchers at The Ohio State University Wexner Medical Center and College of Medicine led the creation of evidence-based consensus guidelines for genetic testing and counseling for patients with  amyotrophic lateral sclerosis (ALS), a neurodegenerative disease that affects the cells in the brain and spine. These evidence-based, consensus guidelines provide clinicians with a framework for the offer of genetic testing and outline the information that should be provided to persons with ALS before and after testing. In addition, the guidelines provide specific recommendations regarding ...

Study: Admissions policies that consider grades and test scores in context of available opportunities are linked to college success

2023-09-18
Indicators of high school grades and standardized test scores that take into account the levels of school, neighborhood, and family resources available to students are strongly associated with those students’ success in college, according to new research published today. The study, published in AERA Open, a peer-reviewed journal of the American Educational Research Association, emerges against the backdrop of the recent Supreme Court decision to ban race-conscious admissions in higher ...

LAST 30 PRESS RELEASES:

Making lighter work of calculating fluid and heat flow

Normalizing blood sugar can halve heart attack risk

Lowering blood sugar cuts heart attack risk in people with prediabetes

Study links genetic variants to risk of blinding eye disease in premature infants

Non-opioid ‘pain sponge’ therapy halts cartilage degeneration and relieves chronic pain

AI can pick up cultural values by mimicking how kids learn

China’s ecological redlines offer fast track to 30 x 30 global conservation goal

Invisible indoor threats: emerging household contaminants and their growing risks to human health

Adding antibody treatment to chemo boosts outcomes for children with rare cancer

Germline pathogenic variants among women without a history of breast cancer

Tanning beds triple melanoma risk, potentially causing broad DNA damage

Unique bond identified as key to viral infection speed

Indoor tanning makes youthful skin much older on a genetic level

Mouse model sheds new light on the causes and potential solutions to human GI problems linked to muscular dystrophy

The Journal of Nuclear Medicine ahead-of-print tip sheet: December 12, 2025

Smarter tools for peering into the microscopic world

Applications open for funding to conduct research in the Kinsey Institute archives

Global measure underestimates the severity of food insecurity

Child survivors of critical illness are missing out on timely follow up care

Risk-based vs annual breast cancer screening / the WISDOM randomized clinical trial

University of Toronto launches Electric Vehicle Innovation Ontario to accelerate advanced EV technologies and build Canada’s innovation advantage

Early relapse predicts poor outcomes in aggressive blood cancer

American College of Lifestyle Medicine applauds two CMS models aligned with lifestyle medicine practice and reimbursement

Clinical trial finds cannabis use not a barrier to quitting nicotine vaping

Supplemental nutrition assistance program policies and food insecurity

Switching immune cells to “night mode” could limit damage after a heart attack, study suggests

URI-based Global RIghts Project report spotlights continued troubling trends in worldwide inhumane treatment

Neutrophils are less aggressive at night, explaining why nighttime heart attacks cause less damage than daytime events

Menopausal hormone therapy may not pose breast cancer risk for women with BRCA mutations

Mobile health tool may improve quality of life for adolescent and young adult breast cancer survivors

[Press-News.org] Buprenorphine dose and time to discontinuation among patients with opioid use disorder in the era of fentanyl
JAMA Network Open