Traditional chinese medicine compound (tongxinluo) and clinical outcomes of patients with acute myocardial infarction

JAMA

2023-10-24

(Press-News.org) About The Study: In this randomized clinical trial of 3,777 patients with ST-segment elevation myocardial infarction (STEMI; a type of heart attack), the Chinese patent medicine Tongxinluo, as an adjunctive therapy in addition to STEMI guideline-directed treatments, significantly improved both 30-day and 1-year clinical outcomes. Further research is needed to determine the mechanism of action of Tongxinluo in STEMI.

Authors: Yuejin Yang, M.D., Ph.D., and Runlin Gao, M.D., of the Chinese Academy of Medical Sciences and Peking Union Medical College in Beijing, are the corresponding authors.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jama.2023.19524)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

# # #

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2023.19524?guestAccessKey=66aee3a0-78fc-415c-846c-56ca5356da82&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=102423

END

ELSE PRESS RELEASES FROM THIS DATE:

Getting maximum calories in shortest time is the priority for bumblebees

2023-10-24

Research has found that bumblebees make foraging choices to collect the most sugar from flowers in the shortest time – even if that means using more energy in the process – to provide an immediate energy boost for the colony. A new study investigating nectar drinking in one of the most common bumblebees in the UK, Bombus terrestris, has found that when foraging they maximise the amount of nectar sugar they take back to the colony each minute. To make their choices, the bumblebees trade off the time they spend collecting nectar with the energy content of that nectar. This means ...

Incidence and transmission of SARS-CoV-2 in child care centers after COVID-19 vaccines

2023-10-24

About The Study: In this examination of SARS-CoV-2 incidence and transmission in child care centers (CCCs) and students’ households, transmission within CCCs and from children infected at CCCs into households was low in this study that included 83 children in 11 CCCs. These findings suggest that current testing and exclusion recommendations for SARS-CoV-2 in CCCs should be aligned with those for other respiratory viruses with similar morbidity and greater transmission to households. Authors: Timothy R. Shope, ...

Neurodevelopmental outcomes among offspring exposed to corticosteroid and B2-adrenergic agonists in utero

2023-10-24

About The Study: The results of this study of 91,460 mother-offspring pairs found no association between in utero corticosteroid and β2-adrenergic agonist exposure and offspring neurodevelopmental outcomes, regardless of the timing of exposure. Despite the limitations and low power of the study, the findings suggest that corticosteroids and β2-adrenergic agonists are safe for pregnant individuals with asthma and the neurodevelopment of their offspring. Authors: Abir Nagata, Ph.D., of Osaka University in Osaka, Japan, and Toshio Masumoto, Ph.D., of Tottori University ...

Child care centers unlikely source for COVID-19 transmission, study finds

2023-10-24

Children in child care centers are not spreading COVID-19 at significant rates to caregivers or other children at the center, nor to their households, according to a study led by University of Pittsburgh School of Medicine and UPMC Children’s Hospital of Pittsburgh pediatrician-scientists and published today in JAMA Network Open. The findings suggest that recommendations to test symptomatic children for SARS-CoV-2, the virus that causes COVID-19, and keep positive children home from child care for prolonged periods can be revised to align with those for other serious ...

Pew funds 6 teams to advance cutting-edge biomedical research

2023-10-24

PHILADELPHIA—The Pew Charitable Trusts announced today the six pairs of researchers who will make up its 2023 class of Innovation Fund investigators. These 12 acclaimed scientists—all alumni or advisors of Pew’s biomedical programs in the United States and Latin America—will partner on interdisciplinary research projects exploring key questions in human biology and disease. Combining the researchers’ expertise in topics ranging from neuroscience and immunology to cancer biology, these collaborations will help boost scientific discovery and improve human health. “An interdisciplinary approach to research is critical to uncovering scientific breakthroughs ...

Givers to crowdfunding campaigns enjoy vicarious success

2023-10-24

Why would someone decide to give their money to help a stranger bring a creative project to life? Recent research has found that backers of crowdfunding projects participate, in part, because of a sense of indirect success and the feeling that they are contributing to something bigger. Crowdfunding — raising money for a new venture by collecting small amounts from many people — is most often done online, and messaging on the most popular sites reinforces the perception of a more democratic market. But the reality is a bit ...

Climate report: ‘Uncharted territory’ imperils life on Earth

2023-10-24

CORVALLIS, Ore. – An international coalition of climate scientists says in a paper published today that the Earth’s vital signs have worsened beyond anything humans have yet seen, to the point that life on the planet is imperiled. William Ripple, a distinguished professor in the Oregon State University College of Forestry, and former OSU postdoctoral researcher Christopher Wolf are the lead authors of the report, and 10 other U.S. and global scientists are co-authors. “Without actions ...

World Scientists' Climate Report highlights perils as Earth enters "uncharted territory"

2023-10-24

In a year marked by wildfire, catastrophic flooding, and deadly weather events, an international team of scientists has updated its influential 2019 World Scientists Warning of a Climate Emergency report, which has been cosigned by over 15,000 scientists representing 163 countries. According to the team, “life on planet Earth is under siege” and “we are now in uncharted territory.” Writing in the journal BioScience, William Ripple, a distinguished ...

Blood test detects tumors early in families with cancer

2023-10-24

Researchers from The Hospital for Sick Children (SickKids), the Ontario Institute for Cancer Research (OICR) and University Health Network (UHN) have demonstrated that by analyzing patients’ blood samples, they are able to detect cancer earlier in individuals with Li-Fraumeni syndrome, an inherited condition with an almost 100 percent life-time risk of developing cancer. The research, led by Drs. Trevor Pugh and Raymond Kim at Princess Margaret Cancer Centre, UHN and OICR and Dr. David Malkin at SickKids, has been published in Cancer Discovery. The study, which was funded primarily ...

Boston Children’s Hospital receives a contract of up to $9 million from NIH to improve flu vaccines

2023-10-24

Flu season is upon us, and existing vaccines are only ~40-60% effective at reducing the risk of serious illness. While any level of protection against influenza viruses is better than none, there remains a lot of room for improvement of future vaccines. The Precision Vaccines Program (PVP) at Boston Children’s Hospital was awarded a Vaccine Adjuvant Development Program contract (75N93023C00040) from the National Institutes of Health (NIH)/National Institute of Allergy and Infectious Diseases (NIAID) that can extend up to 5 years and $9 million, ...

LAST 30 PRESS RELEASES:

Depression due to politics and its quiet danger to democracy addressed in new book 'The Sad Citizen'

International experts and patients unite to help ensure all patients are fully informed before consenting to new surgical procedures

Findings of study on how illegally manufactured fentanyl enters U.S. contradict common assumptions, undermining efforts to control supply

A new perspective on designing urban low-altitude logistics networks subhead: Balancing cost, safety, and noise through co-evolutionary multi-objective optimization