Racial and ethnic disparities in clinical trial enrollment among women with gynecologic cancer

JAMA Network Open

2023-12-07

(Press-News.org) About The Study: Clinical trial enrollment was lower among certain minoritized racial and ethnic groups in this study of 562,000 women with endometrial, ovarian, or cervical cancer. Continued efforts are needed to address disparate clinical trial enrollment among underrepresented groups.

Authors: Ashley S. Felix, Ph.D., of Ohio State University in Columbus, is the corresponding author.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamanetworkopen.2023.46494)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

# # #

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2023.46494?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=120723

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

END

ELSE PRESS RELEASES FROM THIS DATE:

Opioid prescribing by surgeons

2023-12-07

About The Study: This study found that during 2016 to 2022, the rate and size of opioid prescriptions from U.S. surgeons declined, but these declines were slower after mid-2020 compared with before 2020. During the initial months of the COVID-19 pandemic, the opioid dispensing rate declined, potentially owing to decreased surgical volume, while opioid prescription size increased, potentially because surgeons wrote larger discharge prescriptions owing to barriers to obtaining refills. However, these changes were transient. Authors: Kao-Ping ...

Improving prediction of advanced breast cancer among women of different races and ethnicities

2023-12-07

While regular screenings may decrease the chance of diagnosis of advanced breast cancer in some women and lead to a 20% reduction in breast cancer mortality, other women will be diagnosed with advanced breast cancer despite screening at regular intervals. The chances of being diagnosed with advanced breast cancer are higher among women who are Black or Hispanic/Latinx as well as women who are overweight and obese. In a study publishing December 7, 2023 in JAMA Oncology, UC San Francisco researchers found that regular screening is not always sufficient to prevent an advanced breast cancer diagnosis. To reduce the number of advanced cancer diagnoses, ...

Surgery patients now less likely to get opioids – but decline has slowed

2023-12-07

Post-surgery pain relief has shifted away from opioid-containing medications over the past seven years, but the downward trend has slowed since 2020, a new study shows. Overall, the rate of surgery-related opioid prescriptions dropped by 36% from 2016 to the end of 2022, and the average amount of opioids in those prescriptions dropped by 46%, the study of pharmacy data finds. That combination of declines means that the total amount of opioids dispensed to surgical patients in late 2022 was 66% lower compared with early 2016, according to the findings published in JAMA Network Open by a team from the University of Michigan. But the rate of decline was much faster before the pandemic, ...

Three-day exceptional heatwave in China linked to human-induced climate change

2023-12-07

In June, temperatures in North China hit record breaking heights, with temperatures in Beijing reaching or exceeding 40℃ for three consecutive days. The intensity of such events has increased by at least 1.0℃ due to human-induced climate change. Heatwaves like these will occur twice as likely even under proposed carbon neutral targets and will be 0.5℃ more intense. Current emissions scenario will increase the probability of reoccurrence to over five times this century with a 2.9℃ rise in intensity. A record-breaking heatwave occurred in North China in June, marking the ...

Patients who speak Spanish, identify as Hispanic or experience food and housing insecurity at increased risk for depression, anxiety during radiation treatment

2023-12-07

(Boston)—Depression and anxiety among people living with a cancer diagnosis is a growing clinical and research priority. However, the prevalence of mood disorders in those living with cancer varies due to a multitude of variables such as stage and type of cancer, treatment, age, race and ethnicity. A new study by researchers at Boston University Chobanian & Avedisian School of Medicine has found that Spanish-speaking patients undergoing radiotherapy for breast cancer experienced higher distress levels at baseline compared to English-speakers and that this distress increased over ...

WIC participation helped families better cope with 2022 infant formula shortage

2023-12-07

SPOKANE, Wash. – Families that participated in the WIC program—also known as the Special Supplemental Nutrition Program for Women, Infants and Children—were much less likely to use potentially unsafe infant feeding practices during the 2022 U.S. infant formula shortage than income-eligible families that did not participate. Both WIC participants and non-participants reported being affected by the shortage at similar rates, according to a Washington State University study published in the Journal of the Academy of Nutrition and ...

Early life gene epimutation may cause breast cancer.

2023-12-07

Research reveals that around 20 per cent of all cases of the most severe form of breast cancer may arise from the small group of normal tissue cells carrying an epimutation of a specific gene.Research reveals that around 20 per cent of all cases of the most severe form of breast cancer may arise from the small group of normal tissue cells carrying an epimutation of a specific gene. Cancer is a major health challenge worldwide, affecting many lives. Despite progress in understanding its causes, most cancer forms, including breast cancer, continues to increase in ...

The mechanism of ferroptosis and its related diseases

2023-12-07

In a groundbreaking review titled "The Mechanism of Ferroptosis and its Related Diseases," Feng and his colleagues from the Department of Urology and the Institute of Urology, State Key Laboratory of Biotherapy, and Cancer Center at West China Hospital, Sichuan University, have undertaken a comprehensive investigation of ferroptosis and its intricate relationships with various diseases. This review not only discusses the mechanisms of ferroptosis and its associations with diseases but also underscores the pivotal role of compounds in targeting this regulated cell death process for therapeutic applications. Ferroptosis, initially identified by Dr. Brent R. Stockwell in 2012, gained ...

X-ray method enables micron-resolution imaging of living organisms over long time periods

2023-12-07

WASHINGTON — Researchers have developed an X-ray imaging technique that can produce detailed images of living organisms with a much lower X-ray dose than previously possible. The advance enables small organisms or other sensitive samples to be studied at high resolution over much longer periods, which could reveal new insights into a variety of dynamic processes. The approach is based on phase contrast imaging, which relies not only on the absorption of X-rays in a sample, but also on the wave properties ...

Exercise may boost quality of life for patients with metastatic breast cancer

2023-12-07

SAN ANTONIO – Among patients with metastatic breast cancer, those who took part in a nine-month structured exercise program reported less fatigue and an improved quality of life compared to those who did not undergo the exercise program, according to results from the PREFERABLE-EFFECT trial presented at the San Antonio Breast Cancer Symposium, held December 5-9, 2023. Breast cancer and its treatments can cause side effects, such as fatigue, nausea, pain, and shortness of breath, which can decrease a patient’s health-related quality of life (HR-QoL). For patients with metastatic ...

Racial and ethnic disparities in clinical trial enrollment among women with gynecologic cancer

ELSE PRESS RELEASES FROM THIS DATE:

LAST 30 PRESS RELEASES: