PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Innovation in development of dermatologic drugs approved by the FDA

JAMA Dermatology

2023-12-20
(Press-News.org)

About The Study: Compared with prior decades, the number of new dermatologic drug approvals by the Food and Drug Administration (FDA) increased between 2012 and 2022. Nearly half of these drugs were considered first in class or first in indication, and several were deemed clinically useful or to have high added therapeutic benefit by health technology assessment organizations in Germany, Canada, or France.

Authors: Ravi Gupta, M.D., M.S.H.P., of the Johns Hopkins University School of Medicine in Baltimore, is the corresponding author.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamadermatol.2023.5036)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamadermatology/fullarticle/10.1001/jamadermatol.2023.5036?guestAccessKey=c6e3efa5-5965-40d7-b5e1-3492f765a9f6&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=122023

END



ELSE PRESS RELEASES FROM THIS DATE:

New brain-like transistor mimics human intelligence

New brain-like transistor mimics human intelligence
2023-12-20
Taking inspiration from the human brain, researchers have developed a new synaptic transistor capable of higher-level thinking. Designed by researchers at Northwestern University, Boston College and the Massachusetts Institute of Technology (MIT), the device simultaneously processes and stores information just like the human brain. In new experiments, the researchers demonstrated that the transistor goes beyond simple machine-learning tasks to categorize data and is capable of performing associative learning. Although previous studies have leveraged similar strategies to develop brain-like computing devices, those transistors cannot function outside cryogenic temperatures. The new ...

Home-delivered meals and nursing home placement among people with self-reported dementia

2023-12-20
About The Study: This pilot pragmatic clinical trial included 243 homebound older adults with self- or proxy-reported dementia found a lower although nonsignificant likelihood of nursing home placement among those receiving daily-delivered meals compared with those receiving drop-shipped frozen meals. While this study was not powered to detect meaningful, statistically significant differences in nursing home placement, its feasibility and initial results warrant exploration in an adequately powered trial.  Authors: Kali S. Thomas, Ph.D., of the Brown University School of Public Health in Providence, Rhode Island, is the corresponding author.   To access the embargoed ...

Integrating research and clinical care to uncover secrets of brain development

Integrating research and clinical care to uncover secrets of brain development
2023-12-20
The human brain continues to be built after we are born for far longer than previously recognized, suggests research by Shawn Sorrells, assistant professor of neuroscience in the Kenneth P. Dietrich School of Arts and Sciences. Sorrells’s research on postnatal brain development, published today inthe journal Nature, shines light on fundamental processes that contribute to the development of important brain functions, such as learning, memory and spatial navigation. The new research suggests that a subset of inhibitory neurons within the entorhinal cortex, or EC -- an area of the brain essential for forming memories -- continue ...

Meet 'Coscientist,' your AI lab partner

Meet Coscientist, your AI lab partner
2023-12-20
In less time than it will take you to read this article, an artificial intelligence-driven system was able to autonomously learn about certain Nobel Prize-winning chemical reactions and design a successful laboratory procedure to make them. The AI did all that in just a few minutes — and nailed it on the first try. "This is the first time that a non-organic intelligence planned, designed and executed this complex reaction that was invented by humans," says Carnegie Mellon University chemist and ...

3D atomic details of next-generation alloys revealed for first time

3D atomic details of next-generation alloys revealed for first time
2023-12-20
Alloys, which are materials such as steel that are made by combining two or more metallic elements, are among the underpinnings of contemporary life. They are essential for buildings, transportation, appliances and tools — including, very likely, the device you are using to read this story. In applying alloys, engineers have faced an age-old trade-off common in most materials: Alloys that are hard tend to be brittle and break under strain, while those that are flexible under strain tend to dent easily. Possibilities for sidestepping that trade-off arose about 20 years ago, when researchers first developed medium- and high-entropy alloys, stable materials that combine ...

Catalyzing drug discovery with explainable deep learning

2023-12-20
Scientists have discovered one of the first new classes of antibiotics identified in the past 60 years, and the first discovered leveraging an AI-powered platform built around explainable deep learning. Published in Nature today, the peer-reviewed paper, entitled “Discovery of a structural class of antibiotics with explainable deep learning,” was co-authored by a team of 21 researchers, led by Felix Wong, Ph.D., co-founder of Integrated Biosciences, and James J. Collins, Ph.D., Termeer Professor of Medical Engineering ...

Study unveils a role of mitochondria in dietary fat processing

Study unveils a role of mitochondria in dietary fat processing
2023-12-20
The maintenance of a balanced lipid homeostasis is critical for our health. While consumption of excessive amounts of fatty foods contributes to metabolic diseases such as obesity and atherosclerosis, fat is an indispensable component of our diet. Digested lipids supply the body with essential building blocks and facilitate the absorption of important vitamins. In a new study published in the journal Nature, a team of researchers led by Professor Manolis Pasparakis and their collaborators Professor Aleksandra Trifunovic and Professor Christian Frezza at the Excellence Cluster CECAD of the University of Cologne, and Professor Jörg Heeren ...

Protein secrets unveiled: Newl molecular insight of protein–protein interactions

Protein secrets unveiled: Newl molecular insight of protein–protein interactions
2023-12-20
Researchers from Tokyo Medical and Dental University (TMDU) have developed a new technique allowing the binding interfaces on two interacting proteins to be characterized, and validated it by describing the homophilic interaction between LAMP2A molecules Tokyo, Japan – Proteins are building blocks of our bodies, but they do not work solo. They form partners to facilitate in different biological processes that keep us going. However, analyzing how proteins interact at a molecular level can be challenging. Now, a research team from Japan reveals the secrets behind these “protein partnerships”.  In a study published recently in Protein Science, researchers ...

Alzheimer’s discovery reveals dire effect of toxic tau protein on brain cells

Alzheimer’s discovery reveals dire effect of toxic tau protein on brain cells
2023-12-20
University of Virginia Alzheimer’s researchers have discovered how harmful tau proteins damage the essential operating instructions for our brain cells, a finding which could lead to new treatments.  The toxic protein, the researchers found, warps the shape of the nuclei of nerve cells, or neurons. This alters the function of genes contained inside and reprograms the cells to make more tau. While the protein has long been a prime suspect in Alzheimer’s and other neurodegenerative “tauopathies,” the new research from UVA’s ...

Fraunhofer USA releases Annual Research Report, Focus 2023

2023-12-20
Fraunhofer USA, a leading nonprofit research organization dedicated to applied research and development services, is proud to announce the release of its Annual Report, Focus 2023. The report underscores Fraunhofer USA's commitment to fostering transatlantic collaboration, strengthening university-government partnerships, and driving impactful technology transfer. Transatlantic Collaboration: A Pillar of Innovation In the pursuit of global innovation, Fraunhofer USA continues to play a pivotal role in fostering transatlantic collaboration. The annual report highlights the organization's successful partnerships with Fraunhofer-Gesellschaft research institutes, resulting in groundbreaking ...

LAST 30 PRESS RELEASES:

Making lighter work of calculating fluid and heat flow

Normalizing blood sugar can halve heart attack risk

Lowering blood sugar cuts heart attack risk in people with prediabetes

Study links genetic variants to risk of blinding eye disease in premature infants

Non-opioid ‘pain sponge’ therapy halts cartilage degeneration and relieves chronic pain

AI can pick up cultural values by mimicking how kids learn

China’s ecological redlines offer fast track to 30 x 30 global conservation goal

Invisible indoor threats: emerging household contaminants and their growing risks to human health

Adding antibody treatment to chemo boosts outcomes for children with rare cancer

Germline pathogenic variants among women without a history of breast cancer

Tanning beds triple melanoma risk, potentially causing broad DNA damage

Unique bond identified as key to viral infection speed

Indoor tanning makes youthful skin much older on a genetic level

Mouse model sheds new light on the causes and potential solutions to human GI problems linked to muscular dystrophy

The Journal of Nuclear Medicine ahead-of-print tip sheet: December 12, 2025

Smarter tools for peering into the microscopic world

Applications open for funding to conduct research in the Kinsey Institute archives

Global measure underestimates the severity of food insecurity

Child survivors of critical illness are missing out on timely follow up care

Risk-based vs annual breast cancer screening / the WISDOM randomized clinical trial

University of Toronto launches Electric Vehicle Innovation Ontario to accelerate advanced EV technologies and build Canada’s innovation advantage

Early relapse predicts poor outcomes in aggressive blood cancer

American College of Lifestyle Medicine applauds two CMS models aligned with lifestyle medicine practice and reimbursement

Clinical trial finds cannabis use not a barrier to quitting nicotine vaping

Supplemental nutrition assistance program policies and food insecurity

Switching immune cells to “night mode” could limit damage after a heart attack, study suggests

URI-based Global RIghts Project report spotlights continued troubling trends in worldwide inhumane treatment

Neutrophils are less aggressive at night, explaining why nighttime heart attacks cause less damage than daytime events

Menopausal hormone therapy may not pose breast cancer risk for women with BRCA mutations

Mobile health tool may improve quality of life for adolescent and young adult breast cancer survivors

[Press-News.org] Innovation in development of dermatologic drugs approved by the FDA
JAMA Dermatology