Antibiotic prophylaxis and infective endocarditis incidence following invasive dental procedures

JAMA Cardiology

2024-04-06

(Press-News.org) About The Study: This systematic review and meta-analysis including data on 1.1 million cases of infective endocarditis found that antibiotic prophylaxis was associated with a reduced risk of infective endocarditis following invasive dental procedures in individuals at high risk but not in those at moderate or low/unknown risk. Currently, there is insufficient data to support any benefit of antibiotic prophylaxis in individuals at moderate risk.

Authors: Federica Turati, Ph.D., of the Università degli Studi di Milano in Milan, Italy, and Katherine France, D.M.D., M.B.E., of the University of Pennsylvania in Philadelphia, are the corresponding authors.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamacardio.2024.0873)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflicts of interest and financial disclosures, and funding and support.

# # #

Media advisory: This study is being released to coincide with presentation at the American College of Cardiology’s Annual Scientific Session.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamacardiology/fullarticle/10.1001/jamacardio.2024.0873?guestAccessKey=66be9cf8-263a-4a9d-8432-42280b8a0a49&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=040624

END

ELSE PRESS RELEASES FROM THIS DATE:

A multimodal video-based AI biomarker for aortic stenosis development and progression

2024-04-06

About The Study: In this cohort study of patients without severe aortic stenosis undergoing echocardiography or cardiac magnetic resonance imaging, a new artificial intelligence (AI)-based video biomarker was independently associated with aortic stenosis development and progression, enabling opportunistic risk stratification across cardiovascular imaging modalities as well as potential application on handheld devices. Authors: Rohan Khera, M.D., M.S., of the Yale School of Medicine in New Haven, Connecticut, is the corresponding author. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamacardio.2024.0595) Editor’s ...

Inter-atrial shunts may benefit some heart failure patients while harming others

2024-04-06

Inter-atrial shunts—investigational devices that create a small pathway for blood to pass from the left to the right side of the heart in order to improve heart failure symptoms and outcomes—may be beneficial to heart failure patients with reduced left ventricular ejection fraction (LVEF) but harmful or even deadly for heart failure patients with preserved LVEF, a new Mount Sinai-led study shows. The findings of the RELIEVE-HF trial were announced during the opening late-breaking trial session at the American College of Cardiology Scientific Sessions on Saturday, April 6. This is the first study ...

Prostate cancer screening with PSA, Kallikrein Panel, and MRI

2024-04-06

About The Study: In this preliminary descriptive report from an ongoing randomized clinical trial, one additional high-grade cancer per 196 men and one low-grade cancer per 909 men were detected among those randomized to be invited to undergo a single prostate cancer screening intervention compared with those not invited to undergo screening. These preliminary findings from a single round of screening should be interpreted cautiously, pending results of the study’s primary mortality outcome. Authors: Anssi ...

PSA screening and 15-year prostate cancer mortality

2024-04-06

About The Study: A single invitation for prostate-specific antigen (PSA) screening compared with standard practice without routine screening reduced prostate cancer deaths at a median follow-up of 15 years in this secondary analysis of a randomized clinical trial. However, the absolute reduction in deaths was small. Authors: Richard M. Martin, B.M., B.S., Ph.D., of the University of Bristol in Bristol, United Kingdom, is the corresponding author. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jama.2024.4011) Editor’s ...

Screening with a PSA test has a small impact on prostate cancer deaths but leads to overdiagnosis

2024-04-06

The largest study to date investigating a single invitation to a PSA blood test* to screen for prostate cancer has found it had a small impact on reducing deaths, but also led to overdiagnosis and missed early detection of some aggressive cancers. The CAP trial, published in the Journal of the American Medical Association (JAMA) and carried out by researchers from the universities of Bristol, Oxford and Cambridge, involved over 400,000 men aged 50-69. Just under half received a single invitation for a PSA test as part of the trial. After following up for 15 years, there was a small difference in the number of men who died from prostate cancer between the ...

Five-year interval is safe for prostate cancer screening, research shows

2024-04-06

A simple blood test every five years is sufficient to screen low risk men for prostate cancer, new research has shown. The PSA blood test checks the level of prostate-specific antigen, a marker for prostate cancer. In Europe, only Lithuania routinely screens men for prostate cancer based on their PSA levels, as the test has historically been seen as insufficiently reliable. The German study, presented at the European Association of Urology (EAU) Congress in Paris today [April 6, 2024], involved over 12,500 men aged between 45-50 taking part in the ongoing ...

Urine test halves painful procedures in bladder cancer follow up, new trial shows

2024-04-06

A simple urine test can more than halve the number of cystoscopies necessary to follow up high-risk bladder cancer patients, new research has found. Cystoscopies involve inserting a flexible probe through the urethra into the bladder, which allows a clinician to look at the bladder lining for signs of cancer. While they are predominantly safe procedures, cystoscopies do incur some risk of urinary infections and bleeding. They can also cause pain and discomfort. Initial results from a two-year study, presented today ...

Study: Epilepsy patients benefit from structured 'seizure action plans'

2024-04-06

COLUMBUS, Ohio – A new 16-week study of 204 adult epilepsy patients found that 98% of participants believe that all patients with epilepsy should have a seizure action plan (SAP), regardless of seizure status. These plans can help patients with epilepsy to safely manage seizure emergencies. But healthcare providers don’t always discuss them with their patients. Researchers at The Ohio State University Wexner Medical Center and College of Medicine found that standardizing a structured SAP can help adults with epilepsy safely manage seizures. Study findings published online today in the journal Neurology: Clinical Practice. “Our work suggests that simple discussions between ...

Innovative sensing platform unlocks ultrahigh sensitivity in conventional sensors

2024-04-05

By Shawn Ballard Optical sensors serve as the backbone of numerous scientific and technological endeavors, from detecting gravitational waves to imaging biological tissues for medical diagnostics. These sensors use light to detect changes in properties of the environment they’re monitoring, including chemical biomarkers and physical properties like temperature. A persistent challenge in optical sensing has been enhancing sensitivity to detect faint signals amid noise. New research from Lan Yang, the Edwin H. & Florence G. Skinner Professor in the Preston M. Green Department of Electrical & Systems Engineering in the McKelvey School ...

Dinosaur study challenges Bergmann’s rule

2024-04-05

When you throw dinosaurs into the mix, sometimes you find that a rule simply isn’t. A new study led by scientists at the University of Alaska Fairbanks and the University of Reading calls into question Bergmann’s rule, an 1800s-era scientific principle stating that animals in high-latitude, cooler climates tend to be larger than close relatives living in warmer climates. The fossil record shows otherwise. “Our study shows that the evolution of diverse body sizes in dinosaurs and mammals cannot be reduced to simply being a function of latitude or temperature,” said Lauren Wilson, a UAF graduate student and a lead author ...

Medicaid cuts in the "One Big Beautiful Bill Act" could undermine the coverage, financial well-being, medical care, and health of low-income Americans, and lead to more than 16,500 medically-preventab

AMS Science Preview: Gun violence & weather; NOAA flights improve hurricane forecasts; atmospheric rivers and radio waves

Effect of respiratory phase on three-dimensional quantitative parameters of pulmonary subsolid nodules in low-dose computed tomography screening for lung cancer

Antibiotic prophylaxis and infective endocarditis incidence following invasive dental procedures

ELSE PRESS RELEASES FROM THIS DATE:

LAST 30 PRESS RELEASES: